The Stowers Institute For Medical Research
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  Robert E. Krumlauf, Ph.D.,
Scientific Director
William B. Neaves, Ph.D.,
President/CEO

The Stowers Institute for Medical Research seeks more effective means of preventing and curing disease through basic research on genes and proteins that control fundamental processes of cellular life.

Basic Facts About the Stowers Institute
Fact Sheet

Our Mission
     Scientists at the Institute study the way genes determine biological fate and how they can be altered to prevent, treat, or cure disease. Stowers Institute scientists work to broaden the base of knowledge of specific cellular and molecular changes that may be involved in causing disease. This work is essential to understanding most of the illnesses that now challenge medical science, including cancer, cardiovascular disease, diabetes, dementia, and many more.

Our Research
     Research underway at the Institute relies on animal models such as mice, chick embryos, zebra fish, fruit flies, round worms, and yeast. The reason for using "model species" is that humans have a genetic plan quite similar to that of other species. But, unlike humans, these model species can be grown rapidly and their genes mutated at will. It is by studying the consequences of mutations that scientists are able to determine the function of normal genes. Research is also conducted with cultured human cells, including human embryonic stem cells. Individual scientists at the Stowers Institute generally specialize in the study of specific genes, to determine if or how those genes influence various diseases.

Founders
     In the early 1990’s, Jim and Virginia Stowers began to realize that the mutual fund company Mr. Stowers had founded was making them wealthy far beyond what they or their children could possibly need. Instead of eventually leaving their assets behind for others to make decisions about their use, the Stowers decided to launch their own magnificent endeavor to help humanity by supporting the basic research that promises long-term solutions to cancer and other gene-based diseases.

     Mr. and Mrs. Stowers were motivated to found the Stowers Institute by a combination of their own experiences in surviving cancer (prostate and breast, respectively) and their desire to give future generations better choices for treatment in the face of serious illness.

Financial Support
     In 1994, Mr. and Mrs. Stowers incorporated the Stowers Institute and created its supporting endowments with a gift of $50 million. In the years since, they have made additional gifts, which, together with growth through investment, have brought the value of the endowments to more than $2 billion today. Additionally, interested donors can support basic biomedical research through the Institute's Hope Shares® program.

     The Stowers Institute for Medical Research is classified by the IRS as a Medical Research Organization. It is a Missouri not-for-profit corporation and a 501(c)(3) charitable organization.

Leaders
     In 1999, Robert E. Krumlauf, Ph.D., was named Scientific Director, joining the Institute from England's National Institute for Medical Research at Mill Hill, London. A few months later, William B. Neaves, Ph.D., joined the Institute as President and CEO, coming from the University of Texas Southwestern Medical Center at Dallas . Together Drs. Krumlauf and Neaves have succeeded in recruiting 25 laboratory leaders — brilliant scientists who have given up positions at institutions like Harvard and the Howard Hughes Medical Institute to pursue their research at the Stowers Institute.

People
     Eventually, the Stowers Institute will house more than 30 independent research programs in its Kansas City facility, each with an average of 10-20 scientists, research associates, and technicians totaling approximately 600 people, including other support staff and the administrative team.

     By 2007, the Institute housed 22 independent research programs plus three technology development programs in bioinformatics, proteomics, and imaging, and nearly 350 scientists, research associates, technicians and support staff. Stowers researchers hail from more than 20 countries around they world, and come together each day in collaboration to unravel the mysteries of human health.

     The Stowers scientific staff is supported by about 100 non-scientists who manage everything from accounting to purchasing to facility maintenance, allowing Institute scientists to focus on research.

Facility
     The Stowers Institute opened the doors on a 10-acre research campus in the heart of Kansas City, Missouri in November of 2000. The 600,000-square-foot, $300 million facility houses laboratories, research support facilities, administrative services, and a maintenance team. The Institute acquired the former site of Menorah Hospital in 1995. Renovation of the campus took three years and was financed by 40-year, tax-exempt medical research facilities revenue bonds.

Technology
     The Institute's endowments have enabled the creation of a state-of-the-art research environment that offers scientists cutting-edge technology — technology that enables researchers to work better and faster to answer biological questions and seek more effective ways of preserving health and preventing disease.

     Upon arrival of a new research team, the Institute evaluates what equipment researchers will need to begin their work. If the Institute does not already own that equipment, the best available equipment is purchased.

Builders & Architects
     Construction of the Stowers Institute occurred under the direction of J.E. Dunn Construction Co., the general contractor. The general architect, with primary responsibility for the exterior and overall design, was the Kansas City firm of Peckham Guyton Albers & Viets. MBT Architecture of San Francisco, one of the few architectural firms in the country specializing in research facilities, designed the laboratory spaces and other areas related to research.