Stowers News

Ready, go! Stowers researchers pinpoint the Super Elongation Complex as a major regulator in the coordinated expression of early developmental genes

Jul 15 2011

KANSAS CITY, MO—Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the “Go!”- signal to read their part of the genomic symphony.  An assembly of transcription elongation factors known as Super Elongation Complex, or SEC for short, helps paused RNA polymerases to come online and start transcribing the gene ahead, found researchers at the Stowers Institute for Medical Research.

Control of gene expression: Mediator MED26 shifts an idling polymerase into high gear

Jun 5 2011

KANSAS CITY, MO—Look up “transcription”—the copying of a gene’s DNA into RNA intermediaries—in any old molecular biology text book, and it all seems very simple: RNA polymerase II, the enzyme that catalyzes the reaction, assembles at the start site and starts motoring down the strand, cranking out the RNA ribbon used to construct proteins. But researchers now know that RNA polymerase II often stalls on DNA strands where it was once assumed to just barrel down.

Stowers Institute recruits top scientists in developmental and regenerative biology

Jun 20 2011

KANSAS CITY, MO—Renowned developmental biologist Tatjana Piotrowski, Ph.D., and trailblazing regeneration expert Alejandro Sánchez Alvarado, Ph.D., joined the Stowers Institute for Medical Research, the Institute announced today.

Scott Hawley Elected to the National Academy of Sciences

Jun 6 2011

KANSAS CITY, MO - The Stowers Institute for Medical Research is pleased to announce that Investigator and American Cancer Society Research Professor, R. Scott Hawley, Ph.D., has been elected a member of the National Academy of Sciences (NAS) for his excellence in original scientific research. Membership in the NAS is one of the highest honors given to a scientist or engineer in the United States. Hawley will be inducted into the Academy next April during its 149th annual meeting in Washington, D.C.


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