Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum
Hollin T, Abel S, Falla A, Pasaje CFA, Bhatia A, Hur M, Kirkwood JS, Saraf A, Prudhomme J, de Souza A, Florens L, Niles JC, Le Roch KG. Nat Commun. 2022;13:1275. doi: 1210.1038/s41467-41022-28981-41467.
A putative cap binding protein and the methyl phosphate capping enzyme Bin3/MePCE function in telomerase biogenesis
Paez-Moscoso DJ, Ho DV, Pan L, Hildebrand K, Jensen KL, Levy MJ, Florens L, Baumann P. Nat Commun. 2022;13:1067. doi: 1010.1038/s41467-41022-28545-41469.
Cytidine acetylation yields a hypoinflammatory synthetic messenger RNA
Nance KD, Gamage ST, Alam MM, Yang A, Levy MJ, Link CN, Florens L, Washburn MP, Gu S, Oppenheim JJ, Meier JL. Cell Chem Biol. 2022;29:312-320 e317.
MOCS2 links nucleotide metabolism to nucleoli function
Suganuma T, Swanson SK, Gogol M, Garrett TJ, Florens L, Workman JL. J Mol Cell Biol. 2022;13:838-840.
Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing
Bhattacharya S, Wang S, Reddy D, Shen S, Zhang Y, Zhang N, Li H, Washburn MP, Florens L, Shi Y, Workman JL, Li F. Nat Commun. 2021;12:6452. doi: 6410.1038/s41467-41021-26799-41463.
Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling
Ooi SK, Sato S, Tomomori-Sato C, Zhang Y, Wen Z, Banks CAS, Washburn MP, Unruh JR, Florens L, Conaway RC, Conaway JW. Proc Natl Acad Sci U S A. 2021;118:e2107277118. doi: 2107277110.2107271073/pnas.2107277118.
Decellularization enables functional analysis of ECM remodeling in planarian regeneration
Sonpho E, Mann FG, Jr., Levy M, Ross EJ, Guerrero-Hernandez C, Florens L, Saraf A, Doddihal V, Ounjai P, Sánchez Alvarado A. Mol Cell Proteomics. 2021:100137. doi: 100110.101016/j.mcpro.102021.100137.
Proteome plasticity in response to persistent environmental change
Domnauer M, Zheng F, Li L, Zhang Y, Chang CE, Unruh JR, Conkright-Fincham J, McCroskey S, Florens L, Zhang Y, Seidel C, Fong B, Schilling B, Sharma R, Ramanathan A, Si K, Zhou C. Mol Cell. 2021;81:3294-3309 e3212.
The disordered regions of the methyltransferase SETD2 govern its function by regulating its proteolysis and phase separation
Bhattacharya S, Lange JJ, Levy M, Florens L, Washburn MP, Workman JL. J Biol Chem. 2021:101075.
K63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty2 mediated degradation of EGFR
Zhang P, Zhang Z, Fu Y, Zhang Y, Washburn MP, Florens L, Wu M, Huang C, Hou Z, Mohan M. Cell Death Dis. 2021;12:608.
The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain
Bhattacharya S, Levy MJ, Zhang N, Li H, Florens L, Washburn MP, Workman JL. Nat Commun. 2021;12:1443. doi: 1410.1038/s41467-41021-21663-w.
Genome-Wide Binding Analyses of HOXB1 Revealed a Novel DNA Binding Motif Associated with Gene Repression
Singh NP, De Kumar B, Paulson A, Parrish ME, Scott C, Zhang Y, Florens L, Krumlauf R. [published ahead of print March 4 2021]. Dev Biol. 2021;9.
Harnessing Ionic Selectivity In Acetyltransferase Chemoproteomic Probes
Jing Y, Montano JL, Levy M, Lopez JE, Kung PP, Richardson P, Krajewski K, Florens L, Washburn MP, Meier JL. ACS Chem Biol. 2021;16:27-34.
Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling
Oh S, Lee J, Swanson SK, Florens L, Washburn MP, Workman JL. eLife. 2020;9:e64588. doi: 64510.67554/eLife.64588.
The plasticity of the pyruvate dehydrogenase complex confers a labile structure that is associated with its catalytic activity
Lee J, Oh S, Bhattacharya S, Zhang Y, Florens L, Washburn MP, Workman JL. PLos One. 2020;15:e0243489. doi: 10.1371/journal.pone.0243489.
Driving Integrative Structural Modeling with Serial Capture Affinity Purification
Liu X, Zhang Y, Wen Z, Hao Y, Banks CAS, Lange JJ, Slaughter BD, Unruh JR, Florens L, Abmayr SM, Workman JL, Washburn MP. Proc Natl Acad Sci U S A. 2020;117:31861-31870.
A six-amino-acid motif is a major determinant in functional evolution of HOX1 proteins
Singh NP, De Kumar B, Paulson A, Parrish ME, Zhang Y, Florens L, Conaway JW, Si K, Krumlauf R. Genes Dev. 2020;34:1680-1696.
Generating Topological Protein Interaction Scores and Data Visualization with TopS
Sardiu M, Florens L, Washburn MP. Methods. 2020;184:13-18.
Differential complex formation via paralogs in the human Sin3 protein interaction network
Adams MK, Banks CAS, Thornton JL, Kempf CG, Zhang Y, Miah S, Hao Y, Sardiu ME, Killer M, Hattem GL, Murray A, Katt ML, Florens L, Washburn MP. Mol Cell Proteomics. 2020;19:1468-1484.
b-Catenin and Associated Proteins Regulate Lineage Differentiation in Ground State Mouse Embryonic Stem Cells
Tao F, Soffers J, Hu D, Chen S, Gao X, Zhang Y, Zhao C, Smith SE, Unruh JR, Zhang D, Tsuchiya D, Venkatraman A, Zhao M, Li Z, Qian P, Parmely T, He XC, Washburn M, Florens L, Perry JM, Zeitlinger J, Workman J, Li L. Stem Cell Rep. 2020;15:662-676.
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