Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Mediator structure and rearrangements required for holoenzyme formation
Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias FJ. Nature.2017;544:196-201.
The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells
Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, Florens L, Washburn MP, Stadtfeld M, Pinton P, Pagano M. Nat Cell Biol.2017;19:341-351.
Cytosolic proteostasis through importing of misfolded proteins into mitochondria
Ruan L, Zhou C, Jin E, Kucharavy A, Zhang Y, Wen Z, Florens L, Li R. Nature. 2017;543:443-446.
Identification of Topological Network Modules in Perturbed Protein Interaction Networks
Sardiu ME, Gilmore JM, Groppe B, Florens L, Washburn MP. Identification of Topological Network Modules in Perturbed Protein Interaction Networks. Sci Rep.2017;7:43845. doi: 10.1038/srep43845.
Composition and Function of Mutant Swi/Snf Complexes
Dutta A, Sardiu M, Gogol M, Gilmore J, Zhang D, Florens L, Abmayr SM, Washburn MP, Workman JL. Cell Rep. 2017;18:2124-2134.
Chromatin remodeler Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
Lee J, Shik Choi E, David Seo H, Kang K, Gilmore JM, Florens L, Washburn MP, Choe J, Workman JL, Lee D. Nat Commun.2017;8:14527. doi: 14510.11038/ncomms14527.
Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial Surface
Dowdell AS, Murphy MD, Azodi C, Swanson SK, Florens L, Chen S, Zuckert WR. J Bacteriol.2017;199:e00658-00616. doi: 00610.01128/JB.00658-00616.
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia
Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, Shilatifard A. Cell.2017;168:59-72.e13.
Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme
Sato S, Tomomori-Sato C, Tsai KL, Yu X, Sardiu M, Saraf A, Washburn MP, Florens L, Asturias FJ, Conaway RC, Conaway JW. J Biol Chem.2016;291:26886-26898.
Trio, a Rho Family GEF, interacts with the presynaptic active zone proteins Piccolo and Bassoon.
Terry-Lorenzo RT, Torres VI, Wagh D, Galaz J, Swanson SK, Florens L, Washburn MP, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC. PLoS One. 2016;11:e0167535. doi: 0167510.0161371/journal.pone.0167535.
USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2BUSP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B
Lan X, Atanassov BS, Li W, Zhang Y, Florens L, Mohan RD, Galardy PJ, Washburn MP, Workman JL, Dent SY. Cell Rep.2016;17:2382-2393.
TNIP2 is a hub protein in the NF-&(kappa)B network with both protein and RNA mediated interactions.
Banks CA, Boanca G, Lee ZT, Eubanks CG, Hattem GL, Peak A, Weems LE, Conkright JJ, Florens L, Washburn MP. Mol Cell Proteomics. 2016;15:3435-3449.
Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module
Li W, Atanassov BS, Lan X, Mohan RD, Swanson SK, Farria AT, Florens L, Washburn MP, Workman JL, Dent SY. Mol Cell Biol. 2016;36:2855-2866.
SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes.
Brannan KW, Jin W, Huelga SC, Banks CA, Gilmore JM, Florens L, Washburn MP, Van Nostrand EL, Pratt GA, Schwinn MK, Daniels DL, Yeo GW. Mol Cell. 2016;64:282-293.
The Spliceosomal Protein SF3B5 is a Novel Component of Drosophila SAGA that Functions in Gene Expression Independent of Splicing
Stegeman R, Spreacker PJ, Swanson SK, Stephenson R, Florens L, Washburn MP, Weake VM. J Mol Biol.2016;428:3632-3649.
Dynamic and Combinatorial Landscape of Histone Modifications during the Intraerythrocytic Developmental Cycle of the Malaria Parasite
Saraf A, Cervantes S, Bunnik EM, Ponts N, Sardiu ME, Chung DW, Prudhomme J, Varberg JM, Wen Z, Washburn MP, Florens L, Le Roch KG. J Proteome Res. 2016;15:2787-2801.
The mRNA-bound proteome of the human malaria parasite Plasmodium falciparum
Bunnik EM, Batugedara G, Saraf A, Prudhomme J, Florens L, Le Roch KG. Genome Biol. 2016;17:147.
HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins
Hrecka K, Hao C, Shun MC, Kaur S, Swanson SK, Florens L, Washburn MP, Skowronski J. Proc Natl Acad Sci U S A. 2016;113:E3921-3930.
WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.
Gilmore JM, Sardiu ME, Groppe BD, Thornton JL, Liu X, Dayebgadoh G, Banks CA, Slaughter BD, Unruh JR, Workman JL, Florens L, Washburn MP. PloS One. 2016;11:e0155492. doi: 0155410.0151371/journal.pone.0155492.
The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition
Huang F, Saraf A, Florens L, Kusch T, Swanson SK, Szerszen LT, Li G, Dutta A, Washburn MP, Abmayr SM, Workman JL. Genes Dev. 2016;30:1198-1210.
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