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Publications

Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.

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ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth

Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY.  Mol Cell. 2016;62:558-571.

Proteomic and genomic analyses of the Rvb1 and Rvb2 interaction network upon deletion of R2TP complex components

Lakshminarasimhan M, Boanca G, Banks CA, Hattem GL, Gabriel AE, Groppe BD, Smoyer C, Malanowski KE, Peak A, Florens L, Washburn MP. Mol Cell Proteomics. 2016;15:960-974.

Moco biosynthesis and the ATAC acetyltransferase engage translation initiation by inhibiting latent PKR activity.

Suganuma T, Swanson SK, Florens L, Washburn MP, Workman JL. J Mol Cell Biol. 2015;8:44-50.

Cyclin-dependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State.

Ouyang J, Yu W, Liu J, Zhang N, Florens L, Chen J, Liu H, Washburn M, Pei D, Xie T. J Biol Chem. 2015;290:22782-22794.

Amyloidogenic Oligomerization Transforms Drosophila Orb2 from a Translation Repressor to an Activator.

Khan MR, Li L, Perez-Sanchez C, Saraf A, Florens L, Slaughter BD, Unruh JR, Si K. Cell. 2015;163:1468-1483.

Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism.

Li S, Swanson SK, Gogol M, Florens L, Washburn MP, Workman JL, Suganuma T. Mol Cell. 2015;60:408-421.

TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.

Masuda Y, Takahashi H, Sato S, Tomomori-Sato C, Saraf A, Washburn MP, Florens L, Conaway RC, Conaway JW, Hatakeyama S. Nat Commun. 2015;6:7299. doi: 7210.1038/ncomms8299.

Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses.

Weems JC, Slaughter BD, Unruh JR, Hall SM, McLaird MB, Gilmore JM, Washburn MP, Florens L, Yasukawa T, Aso T, Conaway JW, Conaway RC. J Biol Chem. 2015;290:15030-15041.

CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.

Yan J, Hao C, DeLucia M, Swanson S, Florens L, Washburn MP, Ahn J, Skowronski J. J Biol Chem. 2015;209:13279-13292.

Proteins interacting with cloning scars: a source of false positive protein-protein interactions.

Banks CAS, Boanca G, Lee ZT, Florens L, Washburn MP. Sci Rep. 2015;5:8530. doi:10.1038/srep08530

Zic2 is an enhancer-binding factor required for embryonic stem cell specification.

Luo Z, Gao X, Lin C, Smith ER, Marshall SA, Swanson SK, Florens L, Washburn MP, Shilatifard A. Mol Cell. 2015;57:685-694.

The Integrator complex controls the termination of transcription at diverse classes of gene targets.

Skaar JR, Ferris AL, Wu X, Saraf A, Khanna KK, Florens L, Washburn MP, Hughes SH, Pagano M. Cell Res. 2015;25:288-305.

Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing.

Liang K, Gao X, Gilmore JM, Florens L, Washburn MP, Smith E, Shilatifard A. Mol Cell Biol. 2015;35:928-938.

Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.

Pagan JK, Marzio A, Jones MJ, Saraf A, Jallepalli PV, Florens L, Washburn MP, Pagano M. Nat Cell Biol. 2015;17:31-43.

Conserved abundance and topological features in chromatin-remodeling protein interaction networks.

Sardiu ME, Gilmore JM, Groppe BD, Herman D, Ramisetty SR, Cai Y, Jin J, Conaway RC, Conaway JW, Florens L, Washburn MP. EMBO Rep. 2015;16:116-126.

Swi/Snf dynamics on stress-responsive genes is governed by competitive bromodomain interactions.

Dutta A, Gogol M, Kim JH, Smolle M, Venkatesh S, Gilmore J, Florens L, Washburn MP, Workman JL. Genes Dev. 2014;29:2314-2330.

The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex.

Hollopeter G, Lange JJ, Zhang Y, Vu TN, Gu M, Ailion M, Lambie EJ, Slaughter BD, Unruh JR, Florens L, Jorgensen EM. eLife (Cambridge). 2014;3:e03648. doi: 10.7554/eLife.03648.

Phosphorylation by Casein Kinase 2 Facilitates Psh1 Protein-assisted Degradation of Cse4 Protein.

Hewawasam GS, Mattingly M, Venkatesh S, Zhang Y, Florens L, Workman JL, Gerton JL. J Biol Chem. 2014;289:29297-29309.

Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.

Herz HM, Morgan M, Gao X, Jackson J, Rickels R, Swanson SK, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. Science. 2014;345:1065-1070.

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