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Publications

Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.

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iCodon customizes gene expression based on the codon composition

Diez M, Medina-Munoz SG, Castellano LA, da Silva Pescador G, Wu Q, Bazzini AA. Sci Rep. 2022;12:12126 doi: 10.1038/s41598-022-15526-7.

Optimized CRISPR-RfxCas13d system for RNA targeting in zebrafish embryos

Hernandez-Huertas L, Kushawah G, Diaz-Moscoso A, Tomas-Gallardo L, Moreno-Sanchez I, da Silva Prescador G, Bazzini AA, Moreno-Mateos MA. STAR-Protocol. 2022;3:101058.  doi: 10.1016/j.xpro.2021.101058..

Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability

Medina-Munoz SG, Kushawah G, Castellano LA, Diez M, DeVore ML, Salazar MJB, Bazzini AA. [published ahead of print January 7 2021]. Genome Biol. 2021;22:14. doi: 10.1186/s13059-020-02251-5.

CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos

Kushawah G, Hernandez-Huertas L, Abugattas-Nunez Del Prado J, Martinez-Morales JR, DeVore ML, Hassan H, Moreno-Sanchez I, Tomas-Gallardo L, Diaz-Moscoso A, Monges DE, Guelfo JR, Theune WC, Brannan EO, Wang W, Corbin TJ, Moran AM, Sanchez Alvarado A, Malaga-Trillo E, Takacs CM, Bazzini AA, Moreno-Mateos MA.  Dev Cell. 2020;54:805-817 e807.

Translation of small downstream ORFs enhances translation of canonical main open reading frames

Wu Q, Wright M, Gogol MM, Bradford WD, Zhang N, Bazzini AA. EMBO J. 2020;39:e104763. doi: 104710../embj.2020104763.

Translation affects mRNA stability in a codon-dependent manner in human cells

Wu Q, Medina SG, Kushawah G, DeVore ML, Castellano LA, Hand JM, Wright M, Bazzini AA.  eLife. 2019;8:e45396. doi: 45310.47554/eLife.45396.

Casting CRISPR-Cas13d to fish for microprotein functions in animal development

Treichel AJ, Bazzini AA. iScience. 2022;25:105547 doi: 10.1016/j.isci.2022.105547.

Standardized annotation of translated open reading frames

Mudge JM, Ruiz-Orera J, Prensner JR, Brunet MA, Calvet F, Jungreis I, Gonzalez JM, Magrane M, Martinez TF, Schulz JF, Yang YT, Alba MM, Aspden JL, Baranov PV, Bazzini AA, Bruford E, Martin MJ, Calviello L, Carvunis AR, Chen J, Couso JP, Deutsch EW, Flicek P, Frankish A, Gerstein M, Hubner N, Ingolia NT, Kellis M, Menschaert G, Moritz RL, Ohler U, Roucou X, Saghatelian A, Weissman JS, van Heesch S. Nat Biotechnol. 2022;40:994-999.

Poly(A) tails: longer is not always better

Castellano LA, Bazzini AA. Nat Struct Mol Biol. 2017;24:1010-1011.

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