Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Loss of SPECC1L in cranial neural crest cells results in increased hedgehog signaling and frontonasal dysplasia
Tran AJ, Hufft-Martinez BM, Thalman DN, Maili L, McKinney SA, Goering JP, Trainor PA, Saadi I. Front Physiol. 2026;17:1751758.
Retinol dehydrogenase 10-mediated retinoic acid signaling regulates the neural crest cell microenvironment during enteric nervous system formation
Butler Tjaden NE, Shannon SR, Truong THK, Seidel CW, Childers M, Aoto K, Sandell LL, Trainor PA. [published ahead of print January 9 2026]. Hum Mol Genet. 2026.
Oogenesis and germinal bed morphology of the brown anole (A. sagrei)
Kircher BK, Weberling A, Vance EJ, Shylo NA, Starr K, Griffin ZB, Wilson H, McClain M, Hollfelder F, Williams SA, Sanger TJ, Behringer RR, Trainor PA. [published ahead of print January 2026]. Dev Dyn. 2026.
Biophysical processes of morphogenesis in lizard lungs
Hill K, Griffing AH, Palmer MA, Lemma B, Lupo AS, Gamble T, Shylo NA, Kosmrlj A, Trainor PA, Nelson CM. Dev Dyn. 2025.
Gene-environment interactions modulate the phenotypic severity in mouse models of congenital craniofacial syndromes
Fitriasari S, Fiorino R, Truong TH, McKinney MC, Dixon J, Dixon MJ, Trainor PA. J Clin Invest. 2025.
Genomic evolution of EGF-CFC genes in deuterostomes.
Shylo NA, Trainor PA. [published ahead of print June 2025]. Dev Dyn. 2025.
Identification and characterization of short-chain dehydrogenase/reductase 3 (DHRS3) deficiency, a retinoic acid embryopathy of humans
Hashimoto As, Yu J, Williams C, Zueckert-Gaudenz K, Varshosaz P, Zhao R, Pilli N, Liu TY, Russell J, Tooze RS, Twigg SRF, Banka S, Sweeney EW, McGowan SJ, Knight SJL, Taylor JC, Froukh TJ, Palafoll MIV, Martinez-Gil N, Costa-Roger M, Villarreal-Molina MT, Hernandez EL, Jamra RA, Gattermann F, Koch-Hogrebe M, Wieczorek D, Trainor PA, Moise AR, Wilkie AOM, Kane MA. Genet Med Open. 2025;3:103427.
An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo
Demler C, Lawlor JC, Yelin R, Llivichuzcha-Loja D, Shaulov L, Kim D, Stewart M, Lee FK, Shylo N, Trainor PA, Schultheiss TM, Kurpios NA. Elife. 2025;12.
Splicing Defects and Cell Death Cause SF3B2-Linked Craniofacial Microsomia.
Rao S, Watt KEN, Maili L, Lamb M, Farrow E, Hassan H, Weaver K, Miller B, Dash S, Cox LL, Gallacher L, Kant SG, Gibson M, Pastinen T, Li D, Bhoj EJK, Zhu H, Zhang J, Zhang YB, Tan TY, Trainor PA, Cox TC. J Dent Res. 2025:220345251325818.
Pre-oviposition development of the brown anole (Anolis sagrei)
Weberling A, Shylo NA, Kircher BK, Wilson H, McClain M, Marchini M, Starr KB, Sanger TJ, Hollfelder F, Trainor PA. Dev Dyn. 2026;255:145-167.
Cell extrusion drives neural crest cell delamination.
Moore Zajic EL, Zhao R, McKinney MC, Yi K, Wood C, Trainor PA. Proc Natl Acad Sci U S A. 2025;122:e2416566122 doi: 10.1073/pnas.2416566122.
Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination
Zhao R, Moore EL, Gogol MM, Unruh JR, Yu Z, Scott AR, Wang Y, Rajendran NK, Trainor PA. eLife. 2024;13 doi: 10.7554/eLife.92844.
Hypomyelination, hypodontia and craniofacial abnormalities in a Polr3b mouse model of leukodystrophy
Michell-Robinson MA, Watt KEN, Grouza V, Macintosh J, Pinard M, Tuznik M, Chen X, Darbelli L, Wu CL, Perrier S, Chitsaz D, Uccelli NA, Liu H, Cox TC, Muller CW, Kennedy TE, Coulombe B, Rudko DA, Trainor PA, Bernard G. [published ahead of print August 28 2023]. Brain. 2023:1-16.
rRNA transcription is integral to phase separation and maintenance of nucleolar structure
Dash S, Lamb MC, Lange JJ, McKinney MC, Tsuchiya D, Guo F, Zhao X, Corbin TJ, Kirkman M, Delventhal K, Moore EL, McKinney S, Shiang R, Trainor PA. PLoS Genet. 2023;19:e1010854.
POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies
Smallwood K, Watt KEN, Ide S, Baltrunaite K, Brunswick C, Inskeep K, Capannari C, Adam MP, Begtrup A, Bertola DR, Demmer L, Demo E, Devinsky O, Gallagher ER, Guillen Sacoto MJ, Jech R, Keren B, Kussmann J, Ladda R, Lansdon LA, Lunke S, Mardy A, McWalters K, Person R, Raiti L, Saitoh N, Saunders CJ, Schnur R, Skorvanek M, Sell SL, Slavotinek A, Sullivan BR, Stark Z, Symonds JD, Wenger T, Weber S, Whalen S, White SM, Winkelmann J, Zech M, Zeidler S, Maeshima K, Stottmann RW, Trainor PA, Weaver KN. Am J Hum Genet. 2023;110:809-825.
Morphological changes and two Nodal paralogs drive left-right asymmetry in the squamate veiled chameleon (C. calyptratus).
Shylo NA, Smith SE, Price AJ, Guo F, McClain M, Trainor PA. Front Cell Dev Biol. 2023;11:1132166 doi: 10.3389/fcell.2023.1132166.
Nr6a1 controls Hox expression dynamics and is a master regulator of vertebrate trunk development.
Chang YC, Manent J, Schroeder J, Wong SFL, Hauswirth GM, Shylo NA, Moore EL, Achilleos A, Garside V, Polo JM, Trainor P, McGlinn E. Nat Commun. 2022;13:7766 doi: 10.1038/s41467-022-35303-4.
Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse
Guertin TM, Palaria A, Mager J, Sandell LL, Trainor PA, Tremblay KD. Dev Biol. 2022;491:31-42.
Comparative development of limb musculature in phylogenetically and ecologically divergent lizards
Diaz RE, Jr., Taylor-Diaz EA, Trainor PA, Diogo R, Molnar JL. Dev Dyn. 2022:1576-1612.
Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development
Falcon KT, Watt KEN, Dash S, Zhao R, Sakai D, Moore EL, Fitriasari S, Childers M, Sardiu ME, Swanson S, Tsuchiya D, Unruh J, Bugarinovic G, Li L, Shiang R, Achilleos A, Dixon J, Dixon MJ, Trainor PA. Proc Natl Acad Sci U S A. 2022;119:e2116974119 doi: 10.1073/pnas.2116974119.
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