Skip to content Skip to navigation

Alumni

GSSIMR considers the alumni a measure of success for the program. Alumni outcomes like first post-doctoral career placements, publications post-graduation, self-reported career paths, and feedback on preparation are all used to indicate the health and success of the program.

 

Yanfeng He

Thesis Mentors: Joan Conaway, PhD and Ron Conaway, PhD
Thesis: Elongin functions as a loading factor for Mediator at ATFα-regulated ER stress response genes
Thesis Defense Date: August 2021
First Post-Graduate Position: Postdoctoral Researcher, Dana-Farber Cancer Institute, Boston, MA


 
He Y, Sato S, Tomomori-Sato C, Chen S, Goode ZH, Conaway JW, Conaway RC. Proc Natl Acad Sci U S A. 2021;118:e2108751118. doi: 10.1073/pnas.2108751118.

 

Ge X, Rubinstein BY, He Y, Bruce FNO, Li L, Leshansky AM, Li Z. [published ahead of print March 9 2021]. Lab Chip. 2021.

 

Differential gene expression profiling of adult murine hematopoietic stem cells
Park IK, He Y, Lin F, Laerum OD, Tian Q, Bumgarner R, Klug CA, Li K, Kuhr C, Doyle MJ, Xie T, Schummer M, Sun Y, Goldsmith A, Clarke MF, Weissman IL, Hood L, Li L. Blood. 2002;99:488-498.

 

Soon-Keat Ooi

Thesis Mentors: Joan Conaway, PhD and Ron Conaway, PhD
Thesis: Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling
Thesis Defense Date: May 2021
First Post-Graduate Position: Postdoctoral Researcher, Fox Chase Cancer Center, Philadelphia, PA


 
Ooi SK, Sato S, Tomomori-Sato C, Zhang Y, Wen Z, Banks CAS, Washburn MP, Unruh JR, Florens L, Conaway RC, Conaway JW.  Proc Natl Acad Sci U S A. 2021;118:e2107277118. doi: 2107277110.2107271073/pnas.2107277118.

 

Chen L, Ooi SK, Conaway JW, Conaway RC. J Vis Exp. 2014;92:e51721, doi10.3791/51721.

 

Chen L, Ooi SK, Conaway RC, Conaway JW. J Vis Exp. 2014;92:e51720, doi10.3791/51720.

 

Hall N, Karras M, Raine JD, Carlton JM, Kooij TW, Berriman M, Florens L, Janssen CS, Pain A, Christophides GK, James K, Rutherford K, Harris B, Harris D, Churcher C, Quail MA, Ormond D, Doggett J, Trueman HE, Mendoza J, Bidwell SL, Rajandream MA, Carucci DJ, Yates JR, 3rd, Kafatos FC, Janse CJ, Barrell B, Turner CM, Waters AP, Sinden RE. Science.2005;307:82-86.

Zachary Lee

Thesis Mentor: Matt Gibson, PhD
Thesis: In vivo phosphoproteomics uncovers novel requirements for proteins in epithelial growth and division
Thesis Defense Date: December 2020
First Post-Graduate Position: Scientist, Biologics, Catalent, Kansas City, MO


 
Nakajima YI, Lee ZT, McKinney SA, Swanson SK, Florens L, Gibson MC. J Cell Biol. 2019;218:1824-1838.

 

Banks CA, Boanca G, Lee ZT, Eubanks CG, Hattem GL, Peak A, Weems LE, Conkright JJ, Florens L, Washburn MP. Mol Cell Proteomics. 2016;15:3435-3449.
 

 

Banks CAS, Boanca G, Lee ZT, Florens L, Washburn MP. Sci Rep. 2015;5:8530. doi:10.1038/srep08530
 

 

Banks CA, Lee ZT, Boanca G, Lakshminarasimhan M, Groppe BD, Wen Z, Hattem GL, Seidel CW, Florens L, Washburn MP. Mol Cell Proteomics. 2014;13:1510-1522.
 

 

Shuonan He

Thesis Mentor: Matthew Gibson, PhD
Thesis:  A cnidarian perspective on the evolution of body segmentation and segment polarity
Thesis Defense Date: May 2021
First Post-Graduate Position:Postdoctoral Researcher, Harvard University, Cambridge, MA

 


 
Karabulut A, He S, Chen CY, McKinney SA, Gibson MC. Dev Biol. 2019;448:7-15.

 

He S, Grasis JA, Nicotra ML, Juliano CE, Schnitzler CE. EvoDevo. 2019;10:20. doi: 10.1186/s13227-13019-10134-13225.

 

Papagianni A, Fores M, Shao W, He S, Koenecke N, Andreu MJ, Samper N, Paroush Z, Gonzalez-Crespo S, Zeitlinger J, Jimenez G.  Proc Natl Acad Sci U S A.2018;115:1807-1812.

 

He S, Del Viso F, Chen CY, Ikmi A, Kroesen AE, Gibson MC. Science. 2018;361:1377-1380.

 

Guo L, Accorsi A, He S, Guerrero-Hernandez C, Sivagnanam S, McKinney S, Gibson M, Sanchez Alvarado A. BMC Biol. 2018;16:25. doi: 10.1186/s12915-12018-10497-12914.

 

Irina Pushel

Thesis Mentor: Robb Krumlauf, PhD
Thesis: The role of Hoxa2 in specifying the axial identity of mouse cranial neural crest cells
Thesis Defense Date: March 2021
First Post-Graduate Position: Senior Bioinformatic Scientist, Children’s Mercy Hospital, Kansas City, MO


 
Parker HJ, De Kumar B, Pushel I, Bronner ME, Krumlauf R. Dev Biol. 2021:61-76.

 

Kasemeier-Kulesa JC, Schnell S, Woolley T, Spengler JA, Morrison JA, McKinney MC, Pushel I, Wolfe LA, Kulesa PM. Biophys Chem.2018;238:30-38.

 

Parker HJ, Pushel I, Krumlauf R.. Dev Biol. 2018;444 Suppl 1:S67-S78.

 

Darrick Hansen

Thesis Mentor: Linheng Li, PhD
Thesis: Characterization of the Stem Cell Niche and Reserve Stem Cells in the Intestinal Epithelium
Thesis Defense Date: December 2020
First Post-Graduate Position: Postgraduate Researcher, Stowers Institute for Medical Research, Kansas City, MO

 


 
Soffers JH, Hansen D, Sinagoga KL, Li B, Martin MG, Wells J, Grompe M, Li L. Gastroenterology.2016;151:e6-9.

 

Cheng-Yi Chen

Thesis Mentor: Matthew Gibson, PhD
Thesis: The Involvement of Hh Signaling, vasa and nanos in Germline Development of the Sea Anemone Nematostella vectensis
Thesis Defense Date: December 2020
First Post-Graduate Position: Postdoctoral Researcher, Farrell Lab, NIH/NICHD, Bethesda, MD


 

Hedgehog signaling is required for endomesodermal patterning and germ cell development in the sea anemone Nematostella vectensis
Chen CY, McKinney SA, Ellington LR, Gibson MC. eLife. 2020;9:e54573. doi: 54510.54577.54554/eLife.54573.
Original Data

Electroporation of short hairpin RNAs for rapid and efficient gene knockdown in the starlet sea anemone, Nematostella vectensis.
Karabulut A, He S, Chen CY, McKinney SA, Gibson MC. Dev Biol. 2019;448:7-15.
Original Data

 

Xingyu Liu

Thesis Mentor: Jerry Workman, PhD
Thesis: A Novel Affinity Purification Method for Mass Spectrometry Based Protein Complexes Studies: Serial Capture Affinity Purification (SCAP)
Thesis Defense Date: November 2020
First Post-Graduate Position: Postdoctoral Researcher, Washington University, St. Louis, MO

 


 
Liu X, Zhang Y, Wen Z, Hao Y, Banks CAS, Lange JJ, Slaughter BD, Unruh JR, Florens L, Abmayr SM, Workman JL, Washburn MP. Proc Natl Acad Sci U S A. 2020;117:31861-31870.

 

Banks CAS, Thornton JL, Eubanks CG, Adams MK, Miah S, Boanca G, Liu X, Katt ML, Parmely TJ, Florens L, Washburn MP. Mol Cell Proteomics.2018;17:1432-1447.

 

Cassandra Kempf

Thesis Mentors: Michael Washburn, PhD and Jerry Workman, PhD
Thesis: Characterization of MHAP1 as a novel component of MIER1 histone deacetylase complexes
Thesis Defense Date: November 2020
First Post-Graduate Position: Scientist LCMS, Catalent, Kansas City, MO


 

Differential complex formation via paralogs in the human Sin3 protein interaction network
Adams MK, Banks CAS, Thornton JL, Kempf C, Zhang Y, Miah S, Hao Y, Sardiu ME, Killer M, Hattem G, Murray A, Katt M, Florens LA, Washburn MP. [published ahead of print May 30 2020] Mol Cell Proteomics. 2020.
Original Data

BRK Phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG and metastatic potential
Miah S, Banks CAS, Ogunbolude Y, Bagu ET, Berg JM, Saraf A, Tettey TT, Hattem G, Dayebgadoh G, Kempf CG, Sardiu M, Napper S, Florens L, Lukong KE, Washburn MP. Sci Adv. 2019;5:eaaw3113. doi: 3110.1126/sciadv.aaw3113.
Original Data

 

Dayebgadoh Gerald

Thesis Mentor: Jerry Workman, PhD
Thesis: Quantitative Interaction Proteomic Strategies for WDR76 and HP1 Annotation
Thesis Defense Date: October 2020
First Post-Graduate Position:Postgraduate Researcher, Stowers Institute for Medical Research, Kansas City, MO

 


 
Dayebgadoh G, Sardiu ME, Florens L, Washburn MP. J Proteome Res. 2019;18:3479-3491.

 

Eubanks CG, Dayebgadoh G, Liu X, Washburn MP. Expert Rev Proteomics.2017;14:905-915.

 

Gilmore JM, Sardiu ME, Groppe BD, Thornton JL, Liu X, Dayebgadoh G, Banks CA, Slaughter BD, Unruh JR, Workman JL, Florens L, Washburn MP. PloS One. 2016;11:e0155492. doi: 0155410.0151371/journal.pone.0155492.

 

Nicole Nuckolls

Thesis Mentor: Sarah Zanders, PhD
Thesis: Characterization of the ultra-selfish wtf meiotic drivers
Thesis Defense Date: August 2020
First Post-Graduate Position: Postdoctoral Researcher, Julia Cooper Lab, University of Colorado, Colorado
 


 

The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death.
Nuckolls, NL, Mok, AC, Lange, JJ, Yi, K, Kandola, TS, Hunn, AM, McCroskey, S, Snyder, JL, Bravo Núñez, MA, McClain, ML, McKinney, SA, Wood, C, Halfmann, R, and Zanders, SE. bioRxiv 2020.02.05.935874; doi: https://doi.org/10.1101/2020.02.05.935874

wtf genes are prolific dual poison-antidote meiotic drivers
Nuckolls NL*, Bravo Núñez MA*, Eickbush MT, Young JM, Lange JJ, Yu JS, Smith GR, Jaspersen SL, Malik HS, Zanders SE. eLife. 2017;6:e26033. doi: 26010.27554/eLife.26033.
Original Data

Reviews, Commentaries, Chapters or Books
Genetic Villains: Killer Meiotic Drivers
Bravo Nunez MA*, Nuckolls NL*, Zanders SE. [published ahead of print February 27 2018]. Trends Genet.2018.

*contributed equally to this work.

Elisabeth Bauerly

Thesis Mentor: Matthew Gibson, PhD
Thesis: Deciphering the interplay between ciliogenesis and cellular development using microtubule associated proteins during spermatogenesis
Thesis Defense Date: June 2020
First Post-Graduate Position: Postdoctoral Research Associate, Prachee Avasthi Lab, Dartmouth, New Hampshire
 


 

Wampa is a dynein subunit required for axonemal assembly and male fertility in Drosophila
Bauerly E, Yi K, Gibson MC. Dev Biol. 2020;463:158-168.
Original Data

Discovery of Supernumerary B Chromosomes in Drosophila melanogaster.
Bauerly E, Hughes SE, Vietti DR, Miller DE, McDowell W, Hawley RS. Genetics. 2014;196:1007-1016.
Original Data

Gamma-Tubulin Is Required for Bipolar Spindle Assembly and for Proper Kinetochore Microtubule Attachments during Prometaphase I in Drosophila Oocytes.
Hughes SE, Beeler JS, Seat A, Slaughter BD, Unruh JR, Bauerly E, Matthies HJ, Hawley RS. PLoS Genet. 2011;7:e1002209.

 

Jelly Soffers

Thesis Mentor: Jerry Workman, PhD
Thesis: A characterization of the composition and gene-regulatory functions of SAGA-related complexes during Drosophila development
Thesis Defense Date: June 2020
First Post-Graduate Position: Postdoctoral Researcher, Harvard Medical School, Boston, MA
 


 

b-Catenin and Associated Proteins Regulate Lineage Differentiation in Ground State Mouse Embryonic Stem Cells
Tao F, Soffers J, Hu D, Chen S, Gao X, Zhang Y, Zhao C, Smith SE, Unruh JR, Zhang D, Tsuchiya D, Venkatraman A, Zhao M, Li Z, Qian P, Parmely T, He XC, Washburn M, Florens L, Perry JM, Zeitlinger J, Workman J, Li L. Stem Cell Rep. 2020;15:662-676.
Original Data

The SAGA chromatin-modifying complex: the sum of its parts is greater than thewhole
Soffers JHM, Workman JL. Genes Dev. 2020;34:1287-1303.

SAGA Structures Provide Mechanistic Models for Gene Activation
Soffers JHM, Popova VV, Workman JLW. [published ahead of print March 16 2020]. Trends Biochem Sci. 2020.

 

María Angélica Bravo Núñez

Thesis Mentor: Sarah Zanders, PhD
Thesis: The role of meiotic drivers on infertility and the evolution of the chromosome segregation machinery
Thesis Defense Date: March 2020
First Post-Graduate Position: Postdoctoral fellow in Andrew Murray’s lab at Harvard University, Boston, MA


 

Atypical meiosis can be adaptive in outcrossed S. pombe due to wtf meiotic drivers
Bravo Núñez MA, Sabbarini IM, Eide LE, Unckless RL, Zanders SE. eLife. 2020;9:e57936. doi: 57910.57554/eLife.57936.
Original Data

The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death. Nuckolls, NL, Mok, AC, Lange, JJ, Yi, K, Kandola, TS, Hunn, AM, McCroskey, S, Snyder, JL, Bravo Núñez, MA, McClain, ML, McKinney, SA, Wood, C, Halfmann, R, and Zanders, SE. bioRxiv 2020.02.05.935874; doi: https://doi.org/10.1101/2020.02.05.935874

Dramatically diverse Schizosaccharomyces pombe wtf meiotic drivers all display high gamete-killing efficiency
Bravo Núñez MA, Sabbarini IM, Eickbush MT, Liang Y, Lange JJ, Kent AM, Zanders SE. PLoS Genet. 2020;16:e1008350. doi: 1008310.1001371/journal.pgen.1008350.
Original Data

A suppressor of a wtf poison-antidote meiotic driver acts via mimicry of the driver’s antidote
Bravo Núñez MA, Lange JJ, Zanders SE. PLoS Genet. 2018;14:e1007836.  doi: 1007810.1001371/journal.pgen.1007836.
Original Data

wtf genes are prolific dual poison-antidote meiotic drivers
Nuckolls NL*, Bravo Núñez MA*, Eickbush MT, Young JM, Lange JJ, Yu JS, Smith GR, Jaspersen SL, Malik HS, Zanders SE. eLife. 2017;6:e26033. doi: 26010.27554/eLife.26033.
Original Data

Reviews, Commentaries, Chapters or Books
Genetic Villains: Killer Meiotic Drivers
Bravo Nunez MA*, Nuckolls NL*, Zanders SE. [published ahead of print February 27 2018]. Trends Genet.2018.

*contributed equally to this work.

 

Joaquín Navajas Acedo

Thesis Mentor: Tatjana Piotrowski, PhD
Thesis: Dissecting the role of the Planar Cell Polarity (PCP) and Wnt signaling pathways during the establishment of hair cell orientation in zebrafish.
Thesis Defense Date: November 2019
First Post-Graduate Position: Postdoctoral Researcher in the Alexander F. Schier lab at the Biozentrum, University of Basel, Switzerland


 

PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation
Joaquin Navajas Acedo, Matthew G Voas, Richard L Alexander, Thomas Woolley, Jay Unruh, Hua Li, Cecilia Moens, Tatjana Piotrowski. (2019) Nature Communications
Original Data

Evolutionary Origin and Nomenclature of Vertebrate Wnt11-Family Genes
Postlethwait JH, Navajas Acedo J, Piotrowski T. Zebrafish. 2019;16:469-476.

Retinoic acid is required and Fgf, Wnt, and Bmp signaling inhibit posterior lateral line placode induction in zebrafish
Nikaido M, Acedo JN, Hatta K, Piotrowski T. Dev Biol. 2017;431:215-225.
Original Data

Imaging collective cell migration and hair cell regeneration in the sensory lateral line
Venero Galanternik M, Navajas Acedo J, Romero-Carvajal A, Piotrowski T. Methods Cell Biol.2016;134:211-256.
Original Data

Regeneration of Sensory Hair Cells Requires Localized Interactions between the Notch and Wnt Pathways.
Romero-Carvajal A, Navajas Acedo J, Jiang L, Kozlovskaja-Gumbriene A, Alexander R, Li H, Piotrowski T. Dev Cell. 2015;34:267-282.
Original Data

Acrofacial Dysostosis, Cincinnati Type, a Mandibulofacial Dysostosis Syndrome with Limb Anomalies, Is Caused by POLR1A Dysfunction.
Weaver KN, Watt KE, Hufnagel RB, Navajas Acedo J, Linscott LL, Sund KL, Bender PL, Konig R, Lourenco CM, Hehr U, Hopkin RJ, Lohmann DR, Trainor PA, Wieczorek D, Saal HM. Am J Hum Genet. 2015;96:765-774.
Original Data

 

Raquel Barajas Azpeleta

Thesis Mentor: Kausik Si, PhD
Thesis: Modulation of Nervous System Functions: A Surprising Role for Antimicrobial Peptides
Thesis Defense Date: October 2019
First Post-Graduate Position: Postdoctoral Researcher Scholar, Ribeiro Lab, Champalimaud Center for the Unknown, Lisbon, Portugal
 


 

Antimicrobial peptides modulate long-term memory
Barajas-Azpeleta R, Wu J, Gill J, Welte R, Seidel C, McKinney S, Dissel S, Si K. PLoS Genet. 2018;14:e1007440. doi: 1007410.1001371/journal.pgen.1007440.
Original Data

Reviews, Commentaries, Chapters or Books
When mothers leave their mark.
Barajas-Azpeleta R, Si K. eLife. 2019;8:e48899. doi: 48810.47554/eLife.48899..​

 

Amanda Bonner

Thesis Mentor: R. Scott Hawley, PhD
Thesis: The Evolution and Function of Matrimony, a Meiotic Regulator of Polo Kinase
Thesis Defense Date: May 2019
First Post-Graduate Position: Postdoctoral Research Scholar, Singh Lab, University of Oregon

 

 


 

Narya, a RING finger domain-containing protein, is required for both meiotic DNA double-strand break formation and crossover maturation in Drosophila melanogaster
Lake CM, Nielsen RJ, Bonner AM, Eche S, White-Brown S, McKim KS, Hawley RS. PLoS Genet. 2019;15:e1007886. doi: 1007810.1001371/journal.pgen.1007886.​
Original Data

Functional consequences of the evolution of matrimony, a meiosis-specific inhibitor of Polo kinase
Bonner AM, Hawley RS. Mol Biol Evol. 2019;36:69-83.
Original Data

Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains.
Bonner AM, Hughes SE, Chisholm JA, Smith SK, Slaughter BD, Unruh JR, Collins KA, Friederichs JM, Florens L, Swanson SK, Pelot MC, Miller DE, Washburn MP, Jaspersen SL, Hawley RS. Proc Natl Acad Sci U S A. 2013;110:E1222-1231.
Original Data

Reviews, Commentaries, Chapters or Books
A Nucleoporin at the Meiotic Kinetochore
Bonner AM, Hawley RS. Dev Cell. 2016;38:447-448.​

 

Melvin Noé González

Thesis Mentors: Joan Conaway, PhD, and Ron Conaway, PhD
Thesis: Through bubbles, scaffolds and cassettes: Reconstituting the link between Pol II transcription and RNA capping.
Thesis Defense Date: May 2019
First Post-Graduate Position: Postdoctoral Training Fellow, The Francis Crick Institute, London, England


 

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
Noe Gonzalez M, Sato S, Tomomori-Sato C, Conaway JW, Conaway RC. Nat Commun.2018;9:3392. doi: 3310.1038/s41467-41018-05923-w.

Frozen in transcription: Cryo-EM structures of Pol II transcribing through a nucleosome
Noe Gonzalez M, Conaway RC, Conaway JW.  Mol Cell. 2018;72:802-804.

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
Noe Gonzalez, M., Conaway, J. W., & Conaway, R. C.  Journal of Visualized Experiments. (147), e59497.

 

Christine Smoyer

Thesis Mentor: Sue Jaspersen, PhD
Thesis: Analysis of Inner Nuclear Membrane Composition by SPLIT-GFP.
Thesis Defense Date: October 2018
First Post-Graduate Position: Postdoctoral Scholar, Dr. Kassandra Ori-McKenney, Department of Molecular and Cellular Biology, UC Davis, Davis, California
 


 

Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in Saccharomyces cerevisiae.
Smoyer CJ, Smith SE, Gardner JM, McCroskey S, Unruh JR, Jaspersen SL. Genetics. 2019 Feb 1. pii: genetics.301911.2019. doi: 10.1534/genetics.119.301911. [Epub ahead of print]

Analysis of membrane proteins localizing to the inner nuclear envelope in living cells.
Smoyer CJ, Katta SS, Gardner JM, Stoltz L, McCroskey S, Bradford WD, McClain M, Smith SE, Slaughter BD, Unruh JR, Jaspersen SL. J Cell Biol. 2016 Nov 21;215(4):575-590. Epub 2016 Nov 9.

Breaking down the wall: the nuclear envelope during mitosis.
Smoyer CJ, Jaspersen SL. Curr Opin Cell Biol. 2014 Feb;26:1-9. doi: 10.1016/j.ceb.2013.08.002. Epub 2013 Sep 4. Review.

The SUN protein Mps3 controls Ndc1 distribution and function on the nuclear membrane.
Chen J, Smoyer CJ, Slaughter BD, Unruh JR, Jaspersen SL. J Cell Biol. 2014 Feb 17;204(4):523-39. doi: 10.1083/jcb.201307043. Epub 2014 Feb 10.

Destination: inner nuclear membrane.
Katta SS, Smoyer CJ, Jaspersen SL. Trends Cell Biol. 2014 Apr;24(4):221-9. doi: 10.1016/j.tcb.2013.10.006. Epub 2013 Nov 19. Review.

Genetic analysis of Mps3 SUN domain mutants in Saccharomyces cerevisiae reveals an interaction with the SUN-like protein Slp1.
Friederichs JM, Gardner JM, Smoyer CJ, Whetstine CR, Gogol M, Slaughter BD, Jaspersen SL. G3 (Bethesda). 2012 Dec;2(12):1703-18. doi: 10.1534/g3.112.004614. Epub 2012 Dec 1.

Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization.
Ghosh S, Gardner JM, Smoyer CJ, Friederichs JM, Unruh JR, Slaughter BD, Alexander R, Chisholm RD, Lee KK, Workman JL, Jaspersen SL. Mol Biol Cell. 2012 Jul;23(13):2546-59. doi: 10.1091/mbc.E11-07-0600. Epub 2012 May 16.

The SUN protein Mps3 is required for spindle pole body insertion into the nuclear membrane and nuclear envelope homeostasis.
Friederichs JM, Ghosh S, Smoyer CJ, McCroskey S, Miller BD, Weaver KJ, Delventhal KM, Unruh J, Slaughter BD, Jaspersen SL. PLoS Genet. 2011 Nov;7(11):e1002365. doi: 10.1371/journal.pgen.1002365. Epub 2011 Nov 17.

Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z.
Gardner JM, Smoyer CJ, Stensrud ES, Alexander R, Gogol M, Wiegraebe W, Jaspersen SL. J Cell Biol. 2011 May 2;193(3):489-507. doi: 10.1083/jcb.201011017. Epub 2011 Apr 25.

 

Wanqing Shao

Thesis Mentor: Julia Zeitlinger, PhD
Thesis: The interplay between transcription initiation, RNA polymerase II pausing and core promoter elements: A genomics perspective.
Thesis Defense Date: July 2018
First Post-Graduate Position: Postdoctoral Research Associate, Genetics Department, Washington University, St. Louis, MO


 

Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion
Li Z, Qian P, Shao W, Shi H, He XC, Gogol M, Yu Z, Wang Y, Qi M, Zhu Y, Perry JM, Zhang K, Tao F, Zhou K, Hu D, Han Y, Zhao C, Alexander R, Xu H, Chen S, Peak A, Hall K, Peterson M, Perera A, Haug JS, Parmely T, Li H, Shen B, Zeitlinger J, He C, Li L. [published ahead of print August 2 2018]. Cell Res.2018. 28(9):904-917.

Capicua controls Toll/IL-1 signaling targets independently of RTK regulation
Papagianni A, Fores M, Shao W, He S, Koenecke N, Andreu MJ, Samper N, Paroush Z, Gonzalez-Crespo S, Zeitlinger J, Jimenez G.  Proc Natl Acad Sci U S A.2018;115:1807-1812.
Original Data

Paused RNA polymerase II inhibits new transcriptional initiation
Shao W, Zeitlinger J. Nat Genet.2017;49:1045-1051..
Original Data

A global change in RNA Polymerase II pausing during the Drosophila mid bastula transition. eLife 2013 doi: 10.7554/eLife.00861
Chen, K., Johnston, J., Shao, W., Meier, S., Staber, C., and Zeitlinger, J.

 

Cori Cahoon

Thesis Mentor: R. Scott Hawley, PhD
Thesis: Understanding the structure and function of the Drosophila synaptonemal complex in female meiosis.
Thesis Defense Date: April 2018
First Post-Graduate Position: Postdoctoral Researcher, University of Oregon, Eugene, OR


 

Superresolution expansion microscopy reveals the three-dimensional organization of the Drosophila synaptonemal complex.
Cahoon CK, Yu Z, Wang Y, Guo F, Unruh JR, Slaughter BD, Hawley RS. Proc Natl Acad Sci U S A.2017;114:E6857-E6866.

Regulating the construction and demolition of the synaptonemal complex
Cahoon CK, Hawley RS. Nat Struct Mol Biol. 2016;23:369-377.

Meiosis: Cohesins are not just for sisters anymore.
Cahoon CK, Hawley RS. Current Biology. 2016 Jun 11;26(13):R523-5.

Flies get a head start on meiosis.
Cahoon CK, Hawley RS. PLoS Genet. 2013;9:e1004051.

Multiple opposing constraints govern chromosome interactions during meiosis.
Liu DY, Cahoon CK, Burgess S.  PLoS Genet. 2013;9:e1003197

 

Kobe Yuen

Thesis Mentor: Jennifer Gerton, PhD
Thesis: Structural Maintenance Proteins - Roles in Chromatin Organization and Gene Expression
Thesis Defense Date: December 2016
First Post-Graduate Position: Postdoctoral Researcher, Genentech, San Francisco CA

 

"The Stowers graduate program was instrumental in preparing for my position in Genentech. The well-designed modules sparked my interest in studying gene expression on a genomic scale. I then started my project to investigate how genome organization regulates gene expression. I gained skills in bioinformatics and genomics analysis, which greatly facilitates the transition into my postdoc position in which I am analyzing a large amount of genomic data to study disease mechanisms and drug responses."

 


 

Taking cohesin and condensin in context
Yuen KC, Gerton JL. PLoS Genet.2018;14:e1007118. doi: 10.1371/journal.pgen.1007118.

Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports expression of active dense gene clusters
Yuen, KC, Slaughter, BD, andGerton JL. Sci Adv. 2017;3:e1700191. doi: 1700110.1701126/sciadv.1700191. .
Original Data

NIPBL Controls RNA Biogenesis to Prevent Activation of the Stress Kinase PKR.
Yuen KC, Xu B, Krantz, ID, and Gerton, JL (2016) Cell Rep. Jan 5;14(1):93-102.

Etiology and pathogenesis of the cohesinopathies.
Zakari M, Yuen K, Gerton JL. (2015) Wiley Interdiscip Rev Dev Biol. Sep-Oct;4(5):489-504.

Mef2c-F10N enhancer drive β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells. 
Aoto, K, Sandell, L.L., Butler Tjaden, N.E., Yuen, K.C., Watt, K.E., Black B.L., Durnin, M., and Trainor, P.A. (2015) Dev Biol, 402(1):3-16 

From skeleton to cytoskeleton: osteocalcin transforms vascular fibroblasts to myofibroblasts via angiotensin II and Toll-like receptor 4.
Yuen CY, Wong SL, Lau CW, Tsang SY, Xu A, Zhu Z, Ng CF, Yao X, Kong SK, Lee HK, Huang Y. (2012) Circ Res. 111(3):e55-66.

Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.
Yuen, C.Y., Wong, W.T., Tian, X.Y., Wong, S.L., Lau, C. W., Yu, J., Tomlinson, B., Yao, X. and Huang, Y. Cardiovasc Res, 90(1):122-129.