Stowers News

New osteoporosis advance rooted in Stowers research

Jul 8 2019

KANSAS CITY, MOPioneering research from the laboratory of Stowers Investigator Robb Krumlauf, PhD, helped lay the groundwork for a new approach to treating osteoporosis — an often-debilitating disease that affects millions of people worldwide.

Super-resolution microscopy illuminates associations between chromosomes

Jul 3 2019

KANSAS CITY, MOThanks to super-resolution microscopy, scientists have now been able to unambiguously identify physical associations between human chromosomes. The findings have brought to light a new understanding to a curious observation first made more than 50 years ago.

More than a protein factory - A role for ribosomes in regulating human gene expression

May 24 2019

KANSAS CITY, MOResearchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle’s role in destroying healthy mRNAs, the messages that decode DNA into protein.

New method of scoring protein interactions mines large data sets from a fresh angle

Mar 8 2019

KANSAS CITY, MOResearchers from the Stowers Institute for Medical Research have created a novel way to define individual protein associations in a quick, efficient, and informative way. These findings, published in the March 8, 2019, issue of Nature Communications, show how the topological scoring (TopS) algorithm, created by Stowers researchers, can – by combining data sets – identify proteins that come together.

Scientists have identified a bone marrow backup system

Jan 15 2019

KANSAS CITY, MONew research from the Stowers Institute for Medical Research has identified a backup for an important biological system – the hematopoietic system, whose adult stem cells constantly replenish the body’s blood supply.

"Navigator" neurons play critical role in sense of smell

Microspopic image that shows individual olfactory sensory axons
Oct 26 2018

KANSAS CITY, MOResearchers at the Stowers Institute for Medical Research have identified "navigator" neurons that are key to setting up connections in the system responsible for the sense of smell.

New study probes the ancient past of a body plan code

Sep 27 2018

KANSAS CITY, MOResearchers from the Stowers Institute for Medical Research have opened a window on another piece of evolutionary biology. They have found that Hox genes, which are key regulators of the way the bodies of bilaterally symmetrical animals form, also play a role in controlling the radially symmetric body plan of the starlet sea anemone, Nematostella vectensis.

New research opens door to expanding stem cells available for transplants

Aug 3 2018

KANSAS CITY, MOResearchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood (hUCB). This development could make these cells available to more people, and be more readily accepted in those who undergo adult stem cell treatments for conditions such as leukemia, blood disorders, immune system diseases, and other types of cancers, but who do not have an appropriate available bone marrow match.

New model for predicting neuroblastoma outcomes incorporates early developmental signals

Jul 6 2018

KANSAS CITY, MONeuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins. Scientists know that neuroblastoma develops from embryonic neural crest cells that fail to properly migrate or differentiate, but the details about exactly what causes these cells to go astray have been unclear.

New assay reveals biophysical properties that allow certain proteins to infect others

Jul 5 2018

KANSAS CITY, MOScientists at the Stowers Institute for Medical Research have identified a physical basis for the spread of corrupted proteins known as prions inside cells. Their research findings are reported in the July 5, 2018, issue of the scientific journal Molecular Cell.

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