Stowers News

Similarities unite three distinct gene mutations of Treacher Collins Syndrome

Jul 22 2016

KANSAS CITY, MO—Scientists at the Stowers Institute for Medical Research have reported a detailed description of how function-impairing mutations in polr1c and polr1d genes cause Treacher Collins syndrome (TCS), a rare congenital craniofacial development disorder that affects an estimated 1 in 50,000 live births.

Robert Krumlauf elected to the National Academy of Sciences

May 4 2016

KANSAS CITY, MO — The Stowers Institute for Medical Research is pleased to announce that Scientific Director and Investigator Robert Krumlauf, Ph.D., has been elected a member of the National Academy of Sciences (NAS) for his distinguished and continuing achievements in original scientific research. Membership in the NAS is considered one of the highest honors given to a scientist in the United States. Krumlauf will be inducted into the NAS next April during its 154th annual meeting in Washington, D.C.

Researchers generate whole-genome map of fruit fly genetic recombination

Mar 17 2016

KANSAS CITY, MO—As eggs and sperm, or gametes, are formed during meiosis, chromosomes carrying the genetic material from each parent must find their partners, pair, and exchange parts of their DNA. This recombination is an important driving force behind genetic variability and evolution, but most importantly, it ensures that chromosomes move properly during the subsequent divisions that form these gametes.

Researchers use mouse model to study craniofacial disorders

craniofacial disorders study
Feb 25 2016

KANSAS CITY, MO—Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality.

Nomura to purchase a 41 percent stake in American Century Investments

Dec 21 2015

KANSAS CITY, MO—American Century Investments and the Stowers Institute for Medical Research announced today that a non-controlling 41 percent economic interest in American Century currently held by CIBC will be acquired by Nomura, a leading global financial services group with operations in over 30 countries. Under the terms of a definitive agreement signed today, Nomura will purchase the CIBC-held shares for approximately $1 billion.

The worm has turned: new research uncovers processes driving planarian stem cell differentiation in living tissues

Dec 17 2015

KANSAS CITY, MO—With its abundance of stem cells known as neoblasts, and remarkable abilities to restore body parts lost to injury, the humble flatworm, or planaria, has become an exciting model organism to study the processes of tissue and organ regeneration.

Potential biochemical mechanism underlying long-term memories identified

Dec 3 2015

KANSAS CITY, MO—During the holidays, we often remember the past and create new memories. But, why do some memories fade away while others last forever? Scientists at the Stowers Institute for Medical Research have identified a possible biochemical mechanism by which the specialized brain cells known as neurons create and maintain a long-term memory from a fleeting experience.

How a genetic locus protects adult blood-forming stem cells

Dec 1 2015

KANSAS CITY, MO—A particular location in DNA, called the Dlk1-Gtl2 locus, plays a critical role in protecting hematopoietic, or blood-forming, stem cells—a discovery revealing a critical role of metabolic control in adult stem cells, and providing insight for potentially diagnosing and treating cancer, according to researchers from the Stowers Institute for Medica

Protein complex links cellular metabolism to gene expression, offers potential therapeutic target

Oct 29 2015

KANSAS CITY, MO—Researchers in the Workman Lab at the Stowers Institute for Medical Research have identified a link between cellular metabolism and gene expression, one with potentially far-reaching implications for cancer risk prediction and treatment.

Stowers investigator receives Innovation Grant from Alex’s Lemonade Stand Foundation

Oct 14 2015

KANSAS CITY, MO—Neuroblastoma is a solid tumor cancer that arises in the nervous system outside the brain and spinal cord and is often fatal in children. The tumors are derived from embryonic neural crest cells that fail to properly migrate or mature. It is known that a variety of molecular signals guide these processes in the embryo, but it is unclear how defects in these signals contribute to the disease. Stowers Institute Director of Imaging Paul Kulesa, Ph.D., has received an Innovation Grant from Alex’s Lemonade Stand Foundation to pursue this very question.

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