#Stowers25: Celebrating 25 Years
08 October 2025
The future of biology
Why the future of biology depends on widening our lens, embracing joy in discovery, and daring to ask the biggest questions.
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News
The Workman Laboratory received grant funding through a newly established award called Maximizing Investigators' Research Award (MIRA) from the National Institute of General Medical Sciences.
The Workman Laboratory received grant funding through a newly established award called Maximizing Investigators' Research Award (MIRA) from the National Institute of General Medical Sciences. The intent of a MIRA grant is to consolidate multiple project grants into one unified grant that supports the investigators' overall research program, thus providing greater stability and flexibility. MIRA grants are awarded for five years. The MIRA grant awarded to the Workman Lab consolidated previous grants held by Jerry Workman, PhD, and his colleague Susan Abmayr, PhD.
The Workman Lab was awarded a MIRA based on the lab’s research strategy of chromatin modifying complexes that includes a focus on the multi-subunit complexes SAGA and SWI/ SNF. Mutations in these and other complexes have been implicated in cancer and other diseases.
While chromatin modifying complexes can contain as many as 10-20 subunits, an overall view of the assembly and organization of the subunits within the complexes is critical to understanding the effects of mutations. And because mutations of different subunits often do not have the same effects on specific cancers, it is important to understand the individual subunit interactions and how they impact chromatin modifying activity.
#Stowers25: Celebrating 25 Years
08 October 2025
Why the future of biology depends on widening our lens, embracing joy in discovery, and daring to ask the biggest questions.
Read Article
News
08 October 2025
Stowers scientists identify “off” switches carried on some clusters of ribosomal RNA genes that can be passed from parent to child, a unique “fingerprint” of cluster size and activity that may help keep ribosomal RNA production in check.
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In The News
06 October 2025
From the Kansas City Business Journal, Investigator Julia Zeitlinger named "20 to Know"
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