News

05 September 2025
#TechTalk: What is the Computational Biology Technology Center?
A Q&A with Hua Li, Director of Computational Biology, and Madelaine Gogol, Manager, Computational Biology
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The Workman Laboratory received grant funding through a newly established award called Maximizing Investigators' Research Award (MIRA) from the National Institute of General Medical Sciences.
The Workman Laboratory received grant funding through a newly established award called Maximizing Investigators' Research Award (MIRA) from the National Institute of General Medical Sciences. The intent of a MIRA grant is to consolidate multiple project grants into one unified grant that supports the investigators' overall research program, thus providing greater stability and flexibility. MIRA grants are awarded for five years. The MIRA grant awarded to the Workman Lab consolidated previous grants held by Jerry Workman, PhD, and his colleague Susan Abmayr, PhD.
The Workman Lab was awarded a MIRA based on the lab’s research strategy of chromatin modifying complexes that includes a focus on the multi-subunit complexes SAGA and SWI/ SNF. Mutations in these and other complexes have been implicated in cancer and other diseases.
While chromatin modifying complexes can contain as many as 10-20 subunits, an overall view of the assembly and organization of the subunits within the complexes is critical to understanding the effects of mutations. And because mutations of different subunits often do not have the same effects on specific cancers, it is important to understand the individual subunit interactions and how they impact chromatin modifying activity.
News
05 September 2025
A Q&A with Hua Li, Director of Computational Biology, and Madelaine Gogol, Manager, Computational Biology
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#Stowers25: Celebrating 25 Years
21 August 2025
The Stowers Institute celebrates 25 years of discovery, innovation, and hope.
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In The News
19 August 2025
From Nature, Scientists are seeking to decipher the role of non-coding DNA in the human genome, helped by a suite of artificial-intelligence tools.
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