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10 April 2026
BioBasics: What is bioinformatics?
As biology produces more data than ever before, scientists rely on bioinformatics to uncover patterns hidden within DNA, proteins, and other biological systems.
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Bioinformatics and the tools of artificial intelligence

An abstract computational representation of a group of cells.
You’ve likely seen the meme that puts your brain to the test by challenging you to quickly make sense of the following scrambled letters:
fi yuo cna raed this
It’s also likely that you aced the test. The average human brain, always seeking order and meaning, can typically sort the letters into the real words: If you can read this.
The same is true of syntax:
What i if told you
You the read first line wrong
Same the with second
And also the third!
While you likely felt a wave of pride at your ability to decipher the words or phrases, chances are you’ve never attempted to decipher millions or even billions of letters at once. For example, most people would become overwhelmed if asked to decipher this:
sessecorp lacigolob laitnademunf gniyredlnu steercs eht gnirevocnu yB, nac ew dnif evitavonni sehcaorppa ot esongaid, taert, dna tneverp esaesid. lanoitadnuoF hcraeser si erehw seruc nigeb. *
But when it comes to biological research, that’s the challenge posed by experiments that can generate billions of pieces of data. When scientists sequence DNA or map where proteins bind across the genome, they’re not looking at a few data points. They’re looking at massive datasets that are impossible to interpret by eye or even with traditional technologies and computers.
This is where bioinformatics becomes helpful. Bioinformatics is what happens when biology meets computing — it’s a field that helps organize, analyze, and interpret massive amounts of biological data in ways humans cannot. Inside DNA for example, it combines biology, coding, math, and statistics to find meaningful patterns that would remain otherwise hidden.
With recent advances in artificial intelligence, the field is becoming even more important. Biologists now wield powerful new computational tools for tackling the large amounts of data organized by bioinformatics. AI can learn patterns and make predictions more quickly and accurately than a human or a traditional statistical model.
Think of it like this:
Bioinformatics asks the most complex biological questions — and AI is one of the tools we can use to help answer them.
Without bioinformatics, we’d just have mountains of raw data.
But thanks to the field, we can turn that data into real discovery.

An abstract computational representation of a group of cells.
*By the way, if you were wondering, the scrambled phrase above is the Stowers Institute’s mission — and the motivation behind our work: By uncovering the secrets underlying fundamental biological processes, we can find innovative approaches to diagnose, treat, and prevent disease. Foundational research is where cures begin.
Learn more about the impact of our research here.
News
10 April 2026
As biology produces more data than ever before, scientists rely on bioinformatics to uncover patterns hidden within DNA, proteins, and other biological systems.
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News
19 May 2026
For Stowers Investigator Linheng Li, Ph.D., a new leukemia study builds on a career spent asking how the places stem cells call home can shape health, disease, and future treatments
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News

08 May 2026
A new study in Nature, co-authored by Stowers Investigator Ariel Bazzini, Ph.D., demonstrates the human genome may produce thousands of previously overlooked protein-like molecules, challenging long-held definitions of what counts as a protein.
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