Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Beta-catenin cleavage enhances transcriptional activation
Goretsky T, Bradford EM, Ye Q, Lamping OF, Vanagunas T, Moyer MP, Keller PC, Sinh P, Llovet JM, Gao T, She QB, Li L, Barrett TA. Sci Rep.2018;8:671. doi: 10.1038/s41598-017-18421-8.
H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of epithelial cell adhesion molecule
Song Y, Liu C, Liu X, Trottier J, Beaudoin M, Zhang L, Pope C, Peng G, Barbier O, Zhong X, Li L, Wang L. Hepatology.2017;66:1183-1196.
Myo-inositol reduces beta-catenin activation in colitis
Bradford EM, Thompson CA, Goretsky T, Yang GY, Rodriguez LM, Li L, Barrett TA. World J Gastroenterol.2017;23:5115-5126.
Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
Yan KS, Gevaert O, Zheng GXY, Anchang B, Probert CS, Larkin KA, Davies PS, Cheng ZF, Kaddis JS, Han A, Roelf K, Calderon RI, Cynn E, Hu X, Mandleywala K, Wilhelmy J, Grimes SM, Corney DC, Boutet SC, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Wang F, von Furstenberg RJ, Smith NR, Chandrakesan P, May R, Chrissy MAS, Jain R, Cartwright CA, Niland JC, Hong YK, Carrington J, Breault DT, Epstein J, Houchen CW, Lynch JP, Martin MG, Plevritis SK, Curtis C, Ji HP, Li L, Henning SJ, Wong MH, Kuo CJ. Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity. Cell Stem Cell.2017;21:78-90 e76.
Ribosomal DNA copy number loss and sequence variation in cancer
Xu B, Li H, Perry JM, Singh VP, Unruh J, Yu Z, Zakari M, McDowell W, Li L, Gerton JL. PLoS Genet.2017;13:e1006771. doi: 10.1371/journal.pgen.1006771
Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase
Zhang LQ, Van Haandel L, Xiong M, Huang P, Heruth DP, Bi C, Gaedigk R, Jiang X, Li DY, Wyckoff G, Grigoryev DN, Gao L, Li L, Wu M, Leeder JS, Ye SQ. Cell Death Dis.2017;8:e2705. doi: 10.1038/cddis.2017.132.
Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification
Hu D, Gao X, Cao K, Morgan MA, Mas G, Smith ER, Volk AG, Bartom ET, Crispino JD, Di Croce L, Shilatifard A. Mol Cell.2017;65:460-475 e466.
A Putative Biochemical Engram of Long-Term Memory
Li L, Sanchez CP, Slaughter BD, Zhao Y, Khan MR, Unruh JR, Rubinstein B, Si K. Curr Biol.2016;26:3143-3156.
CCAR1 5′ UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance
Li G, Wu X, Qian W, Cai H, Sun X, Zhang W, Tan S, Wu Z, Qian P, Ding K, Lu X, Zhang X, Yan H, Song H, Guang S, Wu Q, Lobie PE, Shan G, Zhu T. Cell Res. 2016.
Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation.
Hervas R, Li L, Majumdar A, Fernandez-Ramirez MD, Unruh JR, Slaughter BD, Galera-Prat A, Santana E, Suzuki M, Nagai Y, Bruix M, Casas-Tinto S, Menendez M, Laurents DV, Si K, Carrion-Vazquez M. PLoS Biol.2016;14:e1002361. doi: 10.1371/journal.pbio.1002361.
Amyloidogenic Oligomerization Transforms Drosophila Orb2 from a Translation Repressor to an Activator.
Khan MR, Li L, Perez-Sanchez C, Saraf A, Florens L, Slaughter BD, Unruh JR, Si K. Cell. 2015;163:1468-1483.
The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.
Qian P, He XC, Paulson A, Li Z, Tao F, Perry JM, Guo F, Zhao M, Zhi L, Venkatraman A, Haug JS, Parmely T, Li H, Dobrowsky RT, Ding WX, Kono T, Ferguson-Smith AC, Li L. Cell Stem Cell. 2016;18:214-228.
A Cytosolic Multiprotein Complex Containing p85alpha Is Required for beta-Catenin Activation in Colitis and Colitis-associated Cancer.
Goretsky T, Bradford EM, Ryu H, Tahir M, Moyer MP, Gao T, Li L, Barrett TA. J Biol Chem. 2016;291:4166-4177.
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation.
Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Sci Rep. 2015;5:8566. doi: 8510.1038/srep08566.
Developmental Programming of Long Non-Coding RNAs during Postnatal Liver Maturation in Mice
Peng L, Paulson A, Li H, Piekos S, He X, Li L. PLoS One. 2014;9:e114917.
Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells.
Zhao M, Perry JM, Marshall H, Venkatraman A, Qian P, He XC, Ahamed J, Li L. Nat Med. 2014;20:1321-1326.
Integrator Regulates Transcriptional Initiation and Pause Release following Activation.
Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R. Mol Cell. 2014;56:128-139.
Leucine-rich Repeat-containing G-protein-coupled Receptor 5 Marks Short-term Hematopoietic Stem and Progenitor Cells during Mouse Embryonic Development.
Liu D, He XC, Qian P, Barker N, Trainor PA, Clevers H, Liu H, Li L. J Biol Chem. 2014;289:23809-23816.
Leukemia Propagating Cells Rebuild an Evolving Niche in Response to Therapy.
Duan CW, Shi J, Chen J, Wang B, Yu YH, Qin X, Zhou XC, Cai YJ, Li ZQ, Zhang F, Yin MZ, Tao Y, Mi JQ, Li LH, Enver T, Chen GQ, Hong DL. Cancer Cell. 2014;25:778-793.
Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway.
Lu R, Wu S, Zhang YG, Xia Y, Liu X, Zheng Y, Chen H, Schaefer KL, Zhou Z, Bissonnette M, Li L, Sun J. Oncogenesis. 2014;3:e105.
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