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Publications

Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.

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Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.

Qu D, May R, Sureban SM, Weygant N, Chandrakesan P, Ali N, Li L, Barrett T, Houchen CW. Am J Physiol Gastrointest Liver Physiol. 2014;306:G404-411.

Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury.

May R, Qu D, Weygant N, Chandrakesan P, Ali N, Lightfoot SA, Li L, Sureban SM, Houchen CW. Stem Cells. 2014;32:822-827.

A Role for H3K4 Monomethylation in Gene Repression and Partitioning of Chromatin Readers.

Cheng J, Blum R, Bowman C, Hu D, Shilatifard A, Shen S, Dynlacht BD. Mol Cell. 2014;53:979-992.

Contribution of Orb2A Stability in Regulated Amyloid-Like Oligomerization of Drosophila Orb2.

White-Grindley E, Li L, Mohammad Khan R, Ren F, Saraf A, Florens L, Si K. PLoS Biol. 2014;12:e1001786.

Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells.

Lei NY, Jabaji Z, Wang J, Joshi VS, Brinkley GJ, Khalil H, Wang F, Jaroszewicz A, Pellegrini M, Li L, Lewis M, Stelzner M, Dunn JC, Martin MG. PLoS One. 2014;9:e84651.

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers.

Hu D, Gao X, Morgan MA, Herz HM, Smith ER, Shilatifard A. Mol Cell Biol. 2013;33:4745-4754.

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells.

Hu D, Garruss AS, Gao X, Morgan MA, Cook M, Smith ER, Shilatifard A. Nat Struct Mol Biol. 2013;20:1092-1097.

Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence.

Venkatraman A, He XC, Thorvaldsen JL, Sugimura R, Perry JM, Tao F, Zhao M, Christenson MK, Sanchez R, Yu JY, Peng L, Haug JS, Paulson A, Li H, Zhong XB, Clemens TL, Bartolomei MS, Li L. Nature. 2013;500:345-349.

A conserved role for atlastin GTPases in regulating lipid droplet size

Klemm RW, Norton JP, Cole RA, Li CS, Park SH, Crane MM, Li L, Jin D, Boye-Doe A, Liu TY, Shibata Y, Lu H, Rapoport TA, Farese RV, Jr., Blackstone C, Guo Y, Mak HY.  Cell Rep.2013;3:1465-1475.

Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay.

Wang F, Scoville D, He XC, Mahe MM, Box A, Perry JM, Smith NR, Lei NY, Davies PS, Fuller MK, Haug JS, McClain M, Gracz AD, Ding S, Stelzner M, Dunn JC, Magness ST, Wong MH, Martin MG, Helmrath M, Li L. Gastroenterology. 2013;145:383-395 e321.

Radiofrequency ablation for dysplasia in Barrett's esophagus restores beta-catenin activation within esophageal progenitor cells.

Krishnan K, Komanduri S, Cluley J, Dirisina R, Sinh P, Ko JZ, Li L, Katzman RB, Barrett TA. Dig Dis Sci. 2012;57:294-302.

Noncanonical wnt signaling maintains hematopoietic stem cells in the niche.

Sugimura R, He XC, Venkatraman A, Arai F, Box A, Semerad C, Haug JS, Peng L, Zhong XB, Suda T, Li L. Cell. 2012;150:351-365.

FGF signaling facilitates post-injury recovery of mouse hematopoietic system.

Zhao M, Ross JT, Itkin T, Perry JM, Venkatraman A, Haug JS, Hembree MJ, Deng CX, Lapidot T, He XC, Li L. Blood. 2012;120:1831-1842.

Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1.

Lee JS, Garrett AS, Yen K, Takahashi YH, Hu D, Jackson J, Seidel C, Pugh BF, Shilatifard A. Genes Dev. 2012; 26:914-919.

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory.

Majumdar A, Cesario WC, White-Grindley E, Jiang H, Ren F, Khan MR, Li L, Choi EM, Kannan K, Guo F, Unruh J, Slaughter B, Si K. Cell. 2012;148:515-529.

Effects of a 28-Day Cage-Change Interval on Intracage Ammonia Levels, Nasal Histology, and Perceived Welfare of CD1 Mice.

Vogelweid CM, Zapien KA, Honigford MJ, Li L, Li H, Marshall H. J Am Assoc Lab Anim Sci. 2011;50:868-878.

Cooperation between both Wnt/ß-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.

Perry JM, He XC, Sugimura R, Grindley JC, Haug JS, Ding S, Li L. Genes Dev. 2011;25:1928-1942.

The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair

Koch S, Nava P, Addis C, Kim W, Denning TL, Li L, Parkos CA, Nusrat A. Gastroenterology. 2011;141:259-268, 268 e251-258.

Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool.

Zhu HH, Ji K, Alderson N, He Z, Li S, Liu W, Zhang DE, Li L, Feng GS. Blood. 2011;117:5350-5361.

MicroRNA programs in normal and aberrant stem and progenitor cells

Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, Li L, Sage J, Zhang DE, Blau HM, Chen C, Chen CZ.  Genome Res. 2011;21:798-810.

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