Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome.Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome
Xu B, Gogol M, Gaudenz K, Gerton JL. BMC Genomics. 2016;17:25.
NIPBL controls RNA biogenesis to prevent activation of the stress kinase PKR.
Yuen KC, Xu B, Krantz ID, Gerton JL. Cell Rep. 2016;14:93-102.
The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity.
Zakari M, Trimble Ross R, Peak A, Blanchette M, Seidel C, Gerton JL. PLoS Genet. 2015;11:E1005308. doi:1005310.1001371/journal.pgen.1005308.
l-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.
Xu B, Sowa N, Cardenas ME, Gerton JL. Hum Mol Genet. 2015;24:1540-1555.
Phosphorylation by Casein Kinase 2 Facilitates Psh1 Protein-assisted Degradation of Cse4 Protein.
Hewawasam GS, Mattingly M, Venkatesh S, Zhang Y, Florens L, Workman JL, Gerton JL. J Biol Chem. 2014;289:29297-29309.
The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription.
Lu S, Lee KK, Harris B, Xiong B, Bose T, Saraf A, Hattem G, Florens L, Seidel C, Gerton JL. EMBO Rep. 2014;15:609-617.
Cohesion promotes nucleolar structure and function.
Harris B, Bose T, Lee KK, Wang F, Lu S, Ross RT, Zhang Y, French SL, Beyer AL, Slaughter BD, Unruh JR, Gerton JL. Mol Biol Cell. 2014;25:337-346.
Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome.
Xu B, Lee KK, Zhang L, Gerton JL. PLoS Genet. 2013:e1003857.
A Genetic Screen to Discover Pathways Affecting Cohesin Function in Schizosaccharomyces pombe Identifies Chromatin Effectors.
Chen Z, McCroskey S, Guo W, Li H, Gerton JL. G3 (Bethesda). 2012;2:1161-1168.
Cell-cycle-coupled structural oscillation of centromeric nucleosomes in yeast.
Shivaraju M, Unruh JR, Slaughter BD, Mattingly M, Berman J, Gerton JL. Cell. 2012;150:304-316.
Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells.
Bose T, Lee KK, Lu S, Xu B, Harris B, Slaughter B, Unruh J, Garrett A, McDowell W, Box A, Li H, Peak A, Ramachandran S, Seidel C, Gerton JL. PLoS Genet. 2012;8:e1002749.
Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization.
Ghosh S, Gardner JM, Smoyer CJ, Friederichs JM, Unruh JR, Slaughter BD, Alexander R, Chisholm RD, Lee KK, Workman JL, Jaspersen SL. Mol Biol Cell. 2012;23:2546-2559.
Scm3 is a centromeric nucleosome assembly factor.
Shivaraju M, Camahort R, Mattingly M, Gerton JL. J Biol Chem. 2011;286:12016-12023.
Psh1 Is an E3 Ubiquitin Ligase that Targets the Centromeric Histone Variant Cse4.
Hewawasam G, Shivaraju M, Mattingly M, Venkatesh S, Martin-Brown S, Florens L, Workman JL, Gerton JL. Mol Cell. 2010;40:444-454.
Hos1 is a lysine deacetylase for the smc3 subunit of cohesin.
Xiong B, Lu S, Gerton JL. Curr Biol. 2010;20:1660-1665.
Eco1 is important for DNA damage repair in S. cerevisiae.
Lu S, Goering M, Gard S, Xiong B, McNairn AJ, Jaspersen SL, Gerton JL. Cell Cycle. 2010;9:3315-3327.
Cohesinopathy mutations disrupt the subnuclear organization of chromatin.
Gard S, Light W, Xiong B, Bose T, McNairn AJ, Harris B, Fleharty B, Seidel C, Brickner JH, Gerton JL. J Cell Biol. 2009;187:455-462.
Cse4 is part of an octameric nucleosome in budding yeast.
Camahort R, Shivaraju M, Mattingly M, Li B, Nakanishi S, Zhu D, Shilatifard A, Workman JL, Gerton JL. Mol Cell. 2009;35:794-805.
Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery.
Oza P, Jaspersen SL, Miele A, Dekker J, Peterson CL. Genes Dev. 2009;23:912-927.
Intersection of ChIP and FLIP, genomic methods to study the dynamics of the cohesin proteins
McNairn AJ, Gerton JL. Chromosome Res. 2009;17:155-163.
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Cse4 gets a kiss-of-death from Psh1.
Hewawasam GS, Gerton JL. Cell Cycle. 2011;10:566-567.
Cohesinopathies, gene expression, and chromatin organization.
Bose T, Gerton JL. J Cell Biol. 2010;189:201-210.
Regulators of the cohesin network.
Xiong B, Gerton JL. Annu Rev Biochem. 2010;79:131-153.
Pushing and pulling: microtubules mediate meiotic pairing and synapsis.
Jaspersen SL, Hawley RS. Cell. 2009;139:861-863.
The chromosome glue gets a little stickier
McNairn AJ, Gerton JL. Trends Genet.2008;24:382-389.
Cohesinopathies: One ring, many obligations
McNairn AJ, Gerton JL. Mutat Res.2008;647:103-111.
Enhancing togetherness: kinetochores and cohesion
Gerton JL. Genes Dev.2007
Chromosome cohesion: a cycle of holding together and falling apart
Gerton J. PLoS Biol.2005
Homologous chromosome interactions in meiosis: diversity amidst conservation
Gerton JL, Hawley RS. Nat Rev Genet.2005;6:477-487.
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