Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Identification of neural crest and melanoma cancer cell invasion and migration genes using high-throughput screening and deep attention networks
Kasemeier-Kulesa JC, Martina Perez S, Baker RE, Kulesa PM. [published ahead of print July 2025]. Dev Dyn. 2025.
Cave Adaptation Favors Aging Resilience in the Mexican Tetra
Cobham AE, Kenzior A, Morales-Sosa P, Javier JE, Swanson S, Wood C, Rohner N. NPJ Metab Health Dis. 2024;3:33.
A genetically tractable non-vertebrate system to study complete camera-type eye regeneration
Accorsi A, Pardo Loredo B, Ross E, Corbin T, McClain M, Weaver K, Delventhal K, Gattamraju A, Morrison J, McKinney MC, McKinney SA, Sánchez Alvarado A. Nat Commun. 2025;16:6698 doi: 10.1038/s41467-025-61681-6.
From Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines
Camacho J, Zhao C, Deng F, Pena V, Morales-Sosa P, Bernal-Rivera A, Yang B, Huang S, Ghosh S, Katt M, Castellano L, Maddera C, Yu Z, Rohner N. Cells. 2025;14:1190 doi: 10.3390/cells14151190.
Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures
Converse A, Perry MJ, Dipali SS, Isola JVV, Kelly EB, Varberg JM, Zelinski MB, Stout MB, Pritchard MT, Duncan FE. PLoS Biol. 2025;23:e3003204.
Population genomics of premature termination codons in cavefish with substantial trait loss
Roback EY, Ferrufino E, Moran RL, Shennard D, Mulliniks C, Gallop J, Weagley J, Miller J, Fily Y, Ornelas-Garcia CP, Rohner N, Kowalko JE, McGaugh SE. Mol Biol Evol. 2025;42.
Genomic evolution of EGF-CFC genes in deuterostomes.
Shylo NA, Trainor PA. [published ahead of print June 2025]. Dev Dyn. 2025.
Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells
Varberg KM, Moreno-Irusta A, Novoa A, Musser B, Varberg JM, Goering JP, Saadi I, Iqbal K, Okae H, Arima T, Williams J, 3rd, Pisarska MD, Soares MJ. Commun Biol. 2025;8:964.
A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms
Swaminathan A, Kenzior A, Price A, Li H, McCoin C, Hintermann A, Weaver K, Morris N, Keene AC, Rohner N. iScience. 2025;28:112874.
Identification and characterization of short-chain dehydrogenase/reductase 3 (DHRS3) deficiency, a retinoic acid embryopathy of humans
Hashimoto As, Yu J, Williams C, Zueckert-Gaudenz K, Varshosaz P, Zhao R, Pilli N, Liu TY, Russell J, Tooze RS, Twigg SRF, Banka S, Sweeney EW, McGowan SJ, Knight SJL, Taylor JC, Froukh TJ, Palafoll MIV, Martinez-Gil N, Costa-Roger M, Villarreal-Molina MT, Hernandez EL, Jamra RA, Gattermann F, Koch-Hogrebe M, Wieczorek D, Trainor PA, Moise AR, Wilkie AOM, Kane MA. Genet Med Open. 2025;3:103427.
A tool to dissect heterotypic determinants of homotypic protein phase behavior
Kimbrough H, Jensen J, Weber C, Miller T, Maddera LE, Blanck JF, Babu VMP, Redwine WB, Halfmann R. Protein Sci. 2025;34:e70194.
Analysis of FAIMS for the study of affinity-purified protein complexes using the orbitrap ascend tribrid mass spectrometer
Goswami P, Cesare J, Rekowski MJ, Clark Z, Thornton J, Washburn MP. Mol Omics. 2025.
Chromatin remodeling protein BPTF mediates chromatin accessibility at gene promoters in planarian stem cells
Verma P, Allen JM, Sanchez Alvarado A, Duncan EM. BMC Genomics. 2025;26:232.
RAP proteins regulate apicoplast noncoding RNA processing in Plasmodium falciparum
Hollin T, Chahine Z, Abel S, Banks C, Pasaje CFA, Lenz T, Prudhomme J, Ybanez CM, Abbaszadeh AS, Niles JC, Florens L, Le Roch KG. Cell Rep. 2025;44:115928 doi: 10.1016/j.celrep.2025.115928.
Splicing Defects and Cell Death Cause SF3B2-Linked Craniofacial Microsomia.
Rao S, Watt KEN, Maili L, Lamb M, Farrow E, Hassan H, Weaver K, Miller B, Dash S, Cox LL, Gallacher L, Kant SG, Gibson M, Pastinen T, Li D, Bhoj EJK, Zhu H, Zhang J, Zhang YB, Tan TY, Trainor PA, Cox TC. J Dent Res. 2025:220345251325818.
Stem and progenitor cell proliferation are independently regulated by cell type-specific cyclinD genes
Lush ME, Tsai YY, Chen S, Munch D, Peloggia J, Sandler JE, Piotrowski T. Nat Commun. 2025;16:5913 doi: 10.1038/s41467-025-60251-0.
Reproductive Adaptation of Astyanax mexicanus Under Nutrient Limitation
Xia F, Santacruz A, Wu D, Bertho S, Fritz E, Morales-Sosa P, McKinney S, Nowotarski SH, Rohner N. Dev Biol. 2025.
Differentially expressed miRNAs offer new perspective into cave adaptation of Astyanax mexicanus
Biswas T, Hassan H, Rohner N. Ann N Y Acad Sci. 2025.
Investigating the Aggregation and Prionogenic Properties of Human Cancer-Related Proteins.
Goncharoff D, Du Z, Venkatesan S, Cho B, Zhao J, Alasady MJ, Huey D, Ma H, Rosenthal J, Turenitsa A, Feldman C, Halfmann R, Mendillo ML, Li L. Mol Cell Biol. 2025;45:154-168.
Complete sequencing of ape genomes
Yoo D, Rhie A, Hebbar P, Antonacci F, Logsdon GA, Solar SJ, Antipov D, Pickett BD, Safonova Y, Montinaro F, Luo Y, Malukiewicz J, Storer JM, Lin J, Sequeira AN, Mangan RJ, Hickey G, Monfort Anez G, Balachandran P, Bankevich A, Beck CR, Biddanda A, Borchers M, Bouffard GG, Brannan E, Brooks SY, Carbone L, Carrel L, Chan AP, Crawford J, Diekhans M, Engelbrecht E, Feschotte C, Formenti G, Garcia GH, de Gennaro L, Gilbert D, Green RE, Guarracino A, Gupta I, Haddad D, Han J, Harris RS, Hartley GA, Harvey WT, Hiller M, Hoekzema K, Houck ML, Jeong H, Kamali K, Kellis M, Kille B, Lee C, Lee Y, Lees W, Lewis AP, Li Q, Loftus M, Loh YHE, Loucks H, Ma J, Mao Y, Martinez JFI, Masterson P, McCoy RC, McGrath B, McKinney S, Meyer BS, Miga KH, Mohanty SK, Munson KM, Pal K, Pennell M, Pevzner PA, Porubsky D, Potapova T, Ringeling FR, Rocha JL, Ryder OA, Sacco S, Saha S, Sasaki T, Schatz MC, Schork NJ, Shanks C, Smeds L, Son DR, Steiner C, Sweeten AP, Tassia MG, Thibaud-Nissen F, Torres-Gonzalez E, Trivedi M, Wei W, Wertz J, Yang M, Zhang P, Zhang S, Zhang Y, Zhang Z, Zhao SA, Zhu Y, Jarvis ED, Gerton JL, Rivas-Gonzalez I, Paten B, Szpiech ZA, Huber CD, Lenz TL, Konkel MK, Yi SV, Canzar S, Watson CT, Sudmant PH, Molloy E, Garrison E, Lowe CB, Ventura M, O'Neill RJ, Koren S, Makova KD, Phillippy AM, Eichler EE. Nature 2025;641:401-418.
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Zeitlinger J, Roy S, Ay F, Mathelier A, Medina-Rivera A, Mahony S, Sinha S, Ernst J. Bioinform Adv. 2025;5:vbaf106.
Embryology 2024: a summer like no other
Abshire KM, Dagher L, Espinoza F, Gupta A, Hammond JE, Lion AT, Merkuri F, Miao Y, Neiro J, Pahima M, Prabhakara C, Sonpho EK, Styfhals R, Trani Bustos M, Zimmer F. Development. 2025;152.
From conservation to adaptation: Understanding the Synaptonemal Complex's evolutionary dynamics.
Williams S, Hawley RS. Curr Opin Genet Dev. 2025;93:102349.
Signalling by co-operative higher-order assembly formation: linking evidence at molecular and cellular levels
Kobe B, Nanson JD, Hoad M, Blumenthal A, Gambin Y, Sierecki E, Stacey KJ, Ve T, Halfmann R. Biochem J. 2025;482:275-294.
