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Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.


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Cavefish mount a rapid and sustained regenerative response following skeletal muscle injury.

Olsen L, Hassan H, Xia F, Keaton S, Rohner N. Zool Res. 2023;44:776-778.

Selection-driven trait loss in independently evolved cavefish populations

Moran RL, Richards EJ, Ornelas-Garcia CP, Gross JB, Donny A, Wiese J, Keene AC, Kowalko JE, Rohner N, McGaugh SE. Nat Commun. 2023;14:2557 doi: 10.1038/s41467-023-37909-8.

Circadian rhythm disruption linked to skeletal muscle dysfunction in the Mexican Cavefish

Olsen L, Krishnan J, Banks C, Hassan H, Rohner N. Curr Biol. 2023;33:R255-R256.

Next generation plasmids for transgenesis in zebrafish and beyond

Kemmler CL, Moran HR, Murray BF, Scoresby A, Klem JR, Eckert RL, Lepovsky E, Bertho S, Nieuwenhuize S, Burger S, D'Agati G, Betz C, Puller AC, Felker A, Ditrychova K, Botschi S, Affolter M, Rohner N, Lovely CB, Kwan KM, Burger A, Mosimann C.[publihsed ahead of print March 29 2023]. Development. 2023.

Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia

Shimobashi M, Thomas A, Shetty S, Frei IC, Wolnerhanssen BK, Weissenberger D, Vandekeere A, Planque M, Dietz N, Ritz D, Meyer-Gerspach AC, Maier T, Hay N, Peterli R, Fendt SM, Rohner N, Hall MN. eLife. 2023;12:e85103.

Divergent evolutionary pathways for aggression and territoriality in Astyanax cavefish

Espinasa L, Collins E, Ornelas-Garcia CP, Retaux S, Rohner N, Rutkowski J.  Subterranean Biol. 2022;43:169-183.

Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation

Krishnan J, Wang Y, Kenzior O, Hassan H, Olsen L, Tsuchiya D, Kenzior A, Peuss R, Xiong S, Wang Y, Zhao C, Rohner N. Sci Rep. 2022;12:10115. doi: 10110.11038/s41598-10022-14507-10110.

The metabolome of Mexican cavefish shows a convergent signature highlighting sugar, antioxidant, and Ageing-Related metabolites

Medley JK, Persons J, Biswas T, Olsen L, Peuss R, Krishnan J, Xiong S, Rohner N. eLife. 2022;11:e74539. doi: 74510.77554/eLife.74539.

Genome-wide analysis of cis-regulatory changes in the metabolic adaptation of cavefish

Krishnan J, Seidel CW, Zhang N, Singh NP, VanCampen J, Peuss R, Xiong S, Kenzior A, Li H, Conaway JW, Rohner N. Nat Genet. 2022;54:684-693.

Enhanced lipogenesis through Ppary helps cavefish adapt to food scarcity

Xiong S, Wang W, Kenzior A, Olsen L, Krishnan J, Persons J, Medley K, Peuss R, Wang Y, Chen S, Zhang N, Thomas N, Miles JM, Sánchez Alvarado A, Rohner N. [published ahead of print April 8 2022].Curr Biol. 2022.

Hybridization underlies localized trait evolution in cavefish

Moran RL, Jaggard JB, Roback EY, Kenzior A, Rohner N, Kowalko JE, Ornelas-Garcia CP, McGaugh SE, Keene AC. iScience. 2022;25:103778. doi: 103710.101016/j.isci.102022.103778.

Pleiotropic function of the oca2 gene underlies the evolution of sleep loss and albinism in cavefish

O'Gorman M, Thakur S, Imrie G, Moran RL, Choy S, Sifuentes-Romero I, Bilandzija H, Renner KJ, Duboue E, Rohner N, McGaugh SE, Keene AC, Kowalko JE. Curr Biol. 2021;31:3694-3701 e3694.

Image3C, a multimodal image-based and label independent integrative method for single-cell analysis

Accorsi A, Box AC, Peuss R, Wood C, Sanchez Alvarado A, Rohner N. eLife. 2021;10. doi: 10.7554/eLife.65372.

Repeated evolution of circadian clock dysregulation in cavefish populations

Mack KL, Jaggard JB, Persons JL, Roback EY, Passow CN, Stanhope BA, Ferrufino E, Tsuchiya D, Smith SE, Slaughter BD, Kowalko J, Rohner N, Keene AC, McGaugh SE. PLoS Genet. 2020;17:e1009642.

A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution

Warren WC, Boggs TE, Borowsky R, Carlson BM, Ferrufino E, Gross JB, Hillier L, Hu Z, Keene AC, Kenzior A, Kowalko JE, Tomlinson C, Kremitzki M, Lemieux ME, Graves-Lindsay T, McGaugh SE, Miller JT, Mommersteeg MTM, Moran RL, Peuss R, Rice ES, Riddle MR, Sifuentes-Romero I, Stanhope BA, Tabin CJ, Thakur S, Yamamoto Y, Rohner N. Nat Commun. 2021;12:1447.

Comparative transcriptome analysis of wild and lab populations of Astyanax mexicanus uncovers differential effects of environment and morphotype on gene expression

Krishnan J, Persons JL, Peuss R, Hassan H, Kenzior A, Xiong S, Olsen L, Maldonado E, Kowalko JE, Rohner N. J Exp Zool B Mol Dev Evol. 2020;334:530-539.

Adaptation to low parasite abundance affects immune investment and immunopathological responses of cavefish

Peuß R, Box AC, Chen S, Wang Y, Tsuchiya D, Persons JL, Kenzior A, Maldonado E, Krishnan J, Scharsack JP, Slaughter BD, Rohner N. Nat Ecol Evol. 2020;4:1416-1430.

An Adult brain atlas reveals broad neuroanatomical changes in independently evolved populations of Mexican cavefish

Loomis C, Peuss R, Jaggard JB, Wang Y, McKinney S, Raftopoulos A, Raftopoulos S, Whu D, Green MR, McGaugh SE, Rohner NE, Keene AC, Duboue ER. Front Neuroanat. 2019;13:88. doi: 10.3389/fnana.2019.00088.

Stable transgenesis in Astyanax mexicanus using the Tol2 transposase system

Stahl BA, Peuss R, McDole B, Kenzior A, Jaggard JB, Gaudenz K, Krishnan J, McGaugh SE, Duboue ER, Keene AC, Rohner N. Dev Dyn. 2019;248:679-687.

Gamete collection and in vitro fertilization of Astyanax mexicanus

Peuss R, Zakibe Z, Krishnan J, Merryman MS, Baumann DP, Rohner N.  J Vis Exp. 2019. doi: 10.3791/59334.

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The cavefish Astyanax mexicanus

Rohner N. Nat Methods. 2023;20:948-950.

Establishment, long-term maintenance, and Characterization of Primary Liver Cells from Astyanax mexicanus

Rajendran N, Deng F, Wang Y, Kenzior O, Krishnan J, Biswas T, Parmely T, Rohner N, Zhao C. Curr Protoc. 2023;3:e736.

Emerging Model Organisms

Wang W, Rohner N, Wang Y, eds. Neuromethods, Springer Protocols: Humana Press. 2023.

Multiplexed Quantitative Proteomics Analysis of Developing Human Brain Organoids

Florens L, Saraf A, Hao Y, Zhang Y, Wang Y, Parmely TJ, Zhao C, Washburn MP. In: W Wang, Y Wang, and N Rohner, eds. Emerging Model Organisms; 2023;194:325-355.

Generation of mini-brains from hiPSCs

Wang Y, Tsuchiya D, Zhao C. In: W Wang, Y Wang, and N Rohner, eds. Emerging model organism. New York, New York: Humana, New Yor, NY; 2023;194:291-306.

Off the deep end: What can deep learning do for the gene expression field?

Raicu AM, Fay JC, Rohner N, Zeitlinger J, Arnosti DN. J Biol Chem. 2023;299:102760.

Poor eyesight reveals a new vision gene

Biswas T, Krishnan J, Rohner N. eLife. 2022;11 doi: 10.7554/eLife.81520.

Lipid metabolism in adaptation to extreme nutritional challenges

Olsen L, Thum E, Rohner N. Dev Cell. 2021;56:1417-1429.

Introduction to the special issue - cavefish - adaptation to the dark

Kowalko JE, Franz-Odendaal TA, Rohner N. J Exp Zoo Pt B Mol Dev Evol. 2020;334:393-396.

Dark world rises: The emergence of cavefish as a model for the study of evolution, development, behavior, and disease.

McGaugh SE, Kowalko JE, Duboue E, Lewis P, Franz-Odendaal TA, Rohner N, Gross JB, Keene AC. J Exp Zool Pt B Mol Dev Evol. 2020;334:397-404.

In the Spotlight-Early Career Researcher

Rohner N. J Exp Zool Pt B Mol Dev Evol. 2020;334:387-388.

Sweet fish: Fish models for the study of hyperglycemia and diabetes

Krishnan J, Rohner N. J Diabetes. 2019;11:193-203.

Evolution: A Dark Past

Rohner N. Curr Biol.2018;28:R1190-R1192

‘Out of the Dark’ Cavefish are Entering Biomedical Research

Rohner N.  Zebrafish, Medaka, and Other Small Fishes - New Model Animals in Biology, Medicine, and Beyond: Springer, Singapore; 2018:253-268.

Seeing a bright future for a blind fish

Gore AV, Rohner N, Retaux S, Jeffery WR. Dev Biol.2018;441:207-208.

Cavefish and the basis for eye loss

Krishnan J, Rohner N. Philos Trans R Soc Lond B Biol Sci.2017;372:20150487. doi: 20150410.20151098/rstb.20152015.20150487.

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