Publications
Publications
Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.
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Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange.
Smolle M, Venkatesh S, Gogol MM, Li H, Zhang Y, Florens L, Washburn MP, Workman JL. Nat Stuct Mol Biol. 2012;19:884-892.
The Cyclin F-Ribonucleotide Reductase M2 axis controls genome integrity and DNA repair.
D'Angiolella V, Donato V, Forrester FM, Jeong Y-T, Kudo Y, Pellacani C, Saraf A, Florens L, Washburn MP, Pagano M. Cell. 2012;149:1023-1034.
Endoplasmic Reticulum Stress-responsive Transcription Factor ATF6α Directs Recruitment of the Mediator of RNA Polymerase II Transcription and Multiple Histone Acetyltransferase Complexes.
Sela D, Chen L, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC. J Biol Chem. 2012;287:23035-23045.
The Super Elongation Complex Family of RNA Polymerase II Elongation Factors: Gene Target Specificity and Transcriptional Output.
Luo Z, Lin C, Guest E, Garrett AS, Mohaghegh N, Swanson S, Marshall S, Florens L, Washburn MP, Shilatifard A. Mol Cell Biol. 2012;32:2608-2617.
The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans.
Yang H, Zhang Y, Vallandingham J, Li H, Florens L, Mak HY. Genes Dev. 2012;26:846-856.
Characterization of a highly conserved histone related protein, ydl156w, and its functional associations using quantitative proteomic analyses.
Gilmore JM, Sardiu ME, Venkatesh S, Stutzman B, Peak A, Seidel CW, Workman JL, Florens L, Washburn MP. Mol Cell Proteomics. 2012;11:M111 011544.
Shaggy/glycogen synthase kinase 3beta and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis.
Takeo S, Swanson SK, Nandanan K, Nakai Y, Aigaki T, Washburn MP, Florens L, Hawley RS. Proc Natl Acad Sci U S A. 2012;109:6382-6389.
A metazoan ATAC acetyltransferase subunit that regulates MAP kinase signaling is related to an ancient molybdopterin synthase component.
Suganuma T, Mushegian A, Swanson SK, Florens L, Washburn MP, Workman JL. Mol Cell Proteomics. 2012;11:90-99.
Polycomb repressive complex 2-dependent and -independent functions of jarid2 in transcriptional regulation in Drosophila.
Herz HM, Mohan M, Garrett AS, Miller C, Casto D, Zhang Y, Seidel C, Haug JS, Florens L, Washburn MP, Yamaguchi M, Shiekhattar R, Shilatifard A. Mol Cell Biol. 2012;32:1683-1693.
The little elongation complex regulates small nuclear RNA transcription.
Smith ER, Lin C, Garrett AS, Thornton J, Mohaghegh N, Hu D, Jackson J, Saraf A, Swanson SK, Seidel C, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. Mol Cell. 2011;44:954-965.
Improving proteomics mass accuracy by dynamic offline lock mass.
Zhang Y, Wen Z, Washburn MP, Florens L. Anal Chem. 2011;83:9344-9351.
Unraveling the ubiquitome of the human malaria parasite.
Ponts N, Saraf A, Chung DW, Harris A, Prudhomme J, Washburn MP, Florens L, Le Roch KG. J Biol Chem. 2011;286:40320-40330.
The COMPASS Family of H3K4 Methylases in Drosophila.
Mohan M, Herz HM, Smith ER, Zhang Y, Jackson J, Washburn MP, Florens L, Eissenberg JC, Shilatifard A. Mol Cell Biol. 2011;31:4310-4318.
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters.
Costessi A, Mahrour N, Tijchon E, Stunnenberg R, Stoel MA, Jansen PW, Sela D, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC, Stunnenberg HG. EMBO J. 2011;30:3786-3798.
Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation.
Weake VM, Dyer JO, Seidel C, Box A, Swanson SK, Peak A, Florens L, Washburn MP, Abmayr SM, Workman JL. Genes Dev. 2011;25:1499-1509.
Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes.
Lee KK, Sardiu ME, Swanson SK, Gilmore JM, Torok M, Grant PA, Florens L, Workman JL, Washburn MP. Mol Syst Biol. 2011;7:503.
Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors.
Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, Conaway RC, Conaway JW. Cell. 2011;146:92-104.
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein.
Hrecka K, Hao C, Gierszewska M, Swanson SK, Kesik-Brodacka M, Srivastava S, Florens L, Washburn MP, Skowronski J. Nature. 2011;474:658-661.
Nuclear cGMP-Dependent Kinase Regulates Gene Expression via Activity-Dependent Recruitment of a Conserved Histone Deacetylase Complex.
Hao Y, Xu N, Box A, Schaefer L, Kannan K, Zhang Y, Florens L, Seidel C, Washburn M, Wiegraebe W, Mak HY. PLoS Genet. 2011;7:e1002065.
DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.
Litovchick L, Florens LA, Swanson SK, Washburn MP, DeCaprio JA. Genes Dev. 2011;25:801-813.
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