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Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.

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A freeze-substitution approach with solvent-based glyoxal fixative to prevent distortion of ocular structures

Pang J, Zhao X, Deng F, Tsuchiya D, Malloy S, Parmely T, Xie T, Wang Y.  [published ahead of print September 16 2022]. J Histotechnol. 2022:1-10.

Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development

Falcon KT, Watt KEN, Dash S, Zhao R, Sakai D, Moore EL, Fitriasari S, Childers M, Sardiu ME, Swanson S, Tsuchiya D, Unruh J, Bugarinovic G, Li L, Shiang R, Achilleos A, Dixon J, Dixon MJ, Trainor PA. Proc Natl Acad Sci U S A. 2022;119:e2116974119 doi: 10.1073/pnas.2116974119.

Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation

Krishnan J, Wang Y, Kenzior O, Hassan H, Olsen L, Tsuchiya D, Kenzior A, Peuss R, Xiong S, Wang Y, Zhao C, Rohner N. Sci Rep. 2022;12:10115. doi: 10110.11038/s41598-10022-14507-10110.

Robust and sensitive in situ RNA detection method using Yn-situ

Wu Y, Xu W, Yu Z, Wang Y, Yu CR. Cell Rep Methods. 2022;2:100201. doi: 100210.101016/j.crmeth.102022.100201.

Enhanced lipogenesis through Ppary helps cavefish adapt to food scarcity

Xiong S, Wang W, Kenzior A, Olsen L, Krishnan J, Persons J, Medley K, Peuss R, Wang Y, Chen S, Zhang N, Thomas N, Miles JM, Sánchez Alvarado A, Rohner N. [published ahead of print April 8 2022].Curr Biol. 2022.

Step-by-step preparation of mouse eye sections for routine histology, immunofluorescence, and RNA in situ hybridization multiplexing

Pang J, Thomas N, Tsuchiya D, Parmely T, Yan D, Xie T, Wang Y. STAR Protoc. 2021;2:100879. doi: 100810.101016/j.xpro.102021.100879..

Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

He X, Smith SE, Chen S, Li H, Wu D, Meneses-Giles PI, Wang Y, Hembree M, Yi K, Zhao X, Guo F, Unruh JR, Maddera LE, Yu Z, Scott A, Perera A, Wang Y, Zhao C, Bae K, Box A, Haug JS, Tao F, Hu D, Hansen DM, Qian P, Saha S, Dixon D, Anant S, Zhang D, Lin EH, Sun W, Wiedemann LM, Li L. Cell Rep. 2021;36:109674.doi: 10.1016/j.celrep.2021.109674.

Repeated evolution of circadian clock dysregulation in cavefish populations

Mack KL, Jaggard JB, Persons JL, Roback EY, Passow CN, Stanhope BA, Ferrufino E, Tsuchiya D, Smith SE, Slaughter BD, Kowalko J, Rohner N, Keene AC, McGaugh SE. PLoS Genet. 2020;17:e1009642.

NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression

Pang J, Le L, Zhou Y, Tu R, Hou Q, Tsuchiya D, Thomas N, Wang Y, Yu Z, Alexander R, Thexton M, Lewis B, Corbin T, Durnin M, Li H, Ashery-Padan R, Yan D, Xie T. Cell Rep. 2021;34:108603. doi: 108610.101016/j.celrep.102020.108603.

wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death

Nuckolls NL, Mok AC, Lange JJ, Yi K, Kandola TS, Hunn AM, McCroskey S, Snyder JL, Bravo Nunez MA, McClain M, McKinney SA, Wood C, Halfmann R, Zanders SE.  eLife. 2020;9:e55694. doi: 55610.57554/eLife.55694.

Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates

Wang W, Hu CK, Zeng A, Alegre D, Hu D, Gotting K, Ortega Granillo A, Wang Y, Robb S, Schnittker R, Zhang S, Alegre D, Li H, Ross E, Zhang N, Brunet A, Sanchez Alvarado A. Science. 2020;369: eaaz3090. doi: 10.1126/science.aaz3090.

Persistent DNA damage and senescense in the placenta impacts developmental outcomes of embryos

Singh VP, McKinney S, Gerton JL. Dev Cell. 2020;54:333-347 e337.

Adaptation to low parasite abundance affects immune investment and immunopathological responses of cavefish

Peuß R, Box AC, Chen S, Wang Y, Tsuchiya D, Persons JL, Kenzior A, Maldonado E, Krishnan J, Scharsack JP, Slaughter BD, Rohner N. Nat Ecol Evol. 2020;4:1416-1430.

Alkaline phosphatase-based chromogenic and fluorescence detection method for BaseScope™ In Situ hybridization

Wang Y, Xu W, Maddera L, Tsuchiya D, Thomas N, Yu CR, Parmely T.  J Histotechnol. 2019;42:193-201.

An Adult brain atlas reveals broad neuroanatomical changes in independently evolved populations of Mexican cavefish

Loomis C, Peuss R, Jaggard JB, Wang Y, McKinney S, Raftopoulos A, Raftopoulos S, Whu D, Green MR, McGaugh SE, Rohner NE, Keene AC, Duboue ER. Front Neuroanat. 2019;13:88. doi: 10.3389/fnana.2019.00088.

Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo

Nil Z, Millan RH, Gerbich T, Leal P, Yu Z, Saraf A, Sardiu M, Lange JJ, Yi K, Unruh J, Slaughter B, Si K. Cell. 2019;178:1403-1420 e1421.

The E3 ubiquitin ligase SINA regulates the assembly and disassembly of the synaptonemal complex in Drosophila females

Hughes SE, Hemenway E, Guo F, Yi K, Yu Z, Hawley RS. PLoS Genet. 2019;15:e1008161. doi: 10.1371/journal.pgen.1008161.

Oocyte-specific deletion of Hdac8 in mice reveals stage-specific effects on fertility

Singh VP, Yueh WT, Gerton JL, Duncan FE. Reproduction. 2019;157:305-316.

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A review on histotechnology practices in Covid-19 pathology investigations

Malloy S, Wang Y. J Histotechnol. 2020;43:153-158.

Seeing the future of Histotechnology through its history

Wang Y.  J Histotechnol. 2018;41:135-136.

Neural crest cells and their application in regenerative medicine

Trainor PA. In: N Antonio, and AR Ten Cate, eds. Ten Cate's Oral Histology - Development, Structure and Function. 9th ed. St. Louis: Elsevier; 2018:21-22.

Immunogold Labeling for Electron Microscopy: Strategy and Problem Solving.

Guo F, Huang BQ. In: ECT Yeung, C Stasolla, MJ Sumner, and BQ Huang, eds. Plant Microtechniques and Protocols: Springer International Publishing; 2015:225-249.

Symmetry breaking and polarity establishment during mouse oocyte maturation.

Yi K, Rubinstein B, Li R. Philos Trans R Soc Lond B Biol Sci. 2013;368:20130002.

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