Past Wednesday Lectures

May 30, 2018
Nicolas Gompel - Ludwig-Maximilians-University of Munich
Regulatory evolution and the diversification of pigmentation patterns in Drosophila
May 23, 2018
Yves Barral - ETH Zurich
Yeast aging as a model for understanding genomic immunity in eukaryotes
May 16, 2018
Ileana Cristea - Princeton University
Virology meets Proteomics: Defining proteome organization and host defense mechanisms during viral infection
May 9, 2018
Wei Yang - National Institutes of Health
Seeing is believing: mechanism for genome maintenance
May 2, 2018
Sue Ackerman - University of California, San Diego
Defects in mRNA translation and neurological disease
April 25, 2018
Antonio Giraldez - Yale University
Deciphering the regulatory codes shaping the maternal to zygotic transition during development
April 18, 2018
Sadie Wignall - Northwestern University
Building a spindle and segregating chromosomes without centrosomes: Oocyte meiosis in C. elegans
April 11, 2018
John Tomich - Kansas State University
Peptide Bilayer-Now Really? What's Next?
April 4, 2018
Utpal Banerjee - University of California, Los Angeles
Metabolic Control of Mammalian Embryonic Development
March 28, 2018
Norbert Perrimon - Harvard Medical School
Interorgan communication
March 21, 2018
Beth Sullivan - Duke University Medical Center
Genomic and epigenetic variation controls human centromere function
March 14, 2018
Mark Krasnow - Stanford University
Elucidating lung stems cells and cancer initiation at single cell resolution
March 7, 2018
Alexander Schier - Harvard University
Induction and lineage in vertebrate development: insights from zebrafish
February 21, 2018
Scott Keeney - Memorial Sloan Kettering Cancer Center
Breaking PAR: Sex chromosome recombination in mouse male meiosis
February 14, 2018
Richard Morimoto - Northwestern University
January 31, 2018
Amy Keating - Massachusetts Institute of Technology
Designing peptides to manipulate Bel02 protein control of cell death
January 24, 2018
James A.J. Fitzpatrick - Washington University, Berkeley
Correlative Microscopy in Studies of Disease Pathogenesis
January 17, 2018
Doris Bachtrog - University of California, Berkeley
Sex chromosomes, chromatin sinks & sex-specific development & aging
December 13, 2017
Tom Misteli - National Cancer Institute/NIH
Deep Imaging of the Genome
December 6, 2017
Timothy Saunders - National University of Singapore
November 29, 2017
Hans Schöler - Max Planck Institute for Molecular Biomedicine in Münster
Induction of pluripotent and multipotent stem cells
November 15, 2017
Angelika Amon - Massachusetts Institute of Technology
The Causes and Consequences of Aneuploidy.
November 8, 2017
Tom Curran - Children's Research Institute
Developing Hedgehog Pathway Inhibitors to Treat Pediatric Brain Tumors: How Basic Science Drives Translation
November 1, 2017
Mitzi Kuroda - Harvard Medical School
The establishment of chromatin domains in normal development and in cancer
October 25, 2017
Nipam Patel - University of California, Berkeley
Evolution and Development: Insights from Emerging Model Systems
October 18, 2017
Michael Galko - University of Texas
Flying Wounded: Using Drosophila to study tissue repair responses
October 11, 2017
Mark Johnson - UMKC School of Dentistry
A Car Accident, High Bone Mass and Muscle-Bone Crosstalk
October 4, 2017
Richard Mann - Columbia University
Scratching beneath the surface of transcription factor-DNA recognition
September 27, 2017
Kevin White - University of Chicago
From Petabytes to Molecular Insights: Building an Operating System for Cancer
September 20, 2017
Nicolas Rohner - Stowers Institute For Medical Research
Bringing light into dark, how cavefish illuminate medicine and evolution
September 13, 2017
Ian Willis - Albert Einstein College of Medicine
Metabolic Impact of Unrestrained Transcription by RNA Polymerase III
September 6, 2017
Eric Kmiec - The Gene Institute - Helen F. Graham Cancer Center & Research Institute
Historical Development and Cellular Regulation of CRISPR-based Gene Editing in Human Cells
May 24, 2017
John Postlethwait - University of Oregon
Genomic revolutions: Antarctic fish and the teleost genome duplication
May 17, 2017
Cassandra Extavour - Harvard University
Alternative model organisms: new tools, new insights into the evolution of development
May 10, 2017
Joel Richter - University of Massachusetts Medical Center
Translational Control of Neurologic Disease
May 3, 2017
Allan Drummond - University of Chicago
How phase separation helps cells react to stress
April 26, 2017
James Briscoe - The Francis Crick Center
The gene regulatory logic of vertebrate neural tube development
April 19, 2017
Steven Pruitt - Rosewell Park Cancer Institute
DNA Replication Licensing in Genome Stability and Cancer
April 12, 2017
Chris Lowe - Stanford University
Uncoupling the evolution of morphology and regulatory networks during the evolution of nervous systems
April 5, 2017
Brian Slaughter and Jay Unruh - Stowers Institute For Medical Reseaerch
In Situ Structural Biology: Expansion, Super-resolution, and Image averaging
March 29, 2017
Jonathan Weissman - HHMI, University of California, San Francisco
Controlling the volume of gene expression with CRISPRi and CRISPRa
March 22, 2017
Monica Bettencourt Dias - Instituto Gulbenkian de Ciencia
Centrosomes in Development, Evolution and Disease
March 15, 2017
Fiona Watt - University of Oxford
Regulating exit from the stem cell compartment in mammalian epidermis
March 8, 2017
Susan Dutcher - Washington University, St. Louis
Dissecting the assembly of cilia
March 1, 2017
Christopher Gregg - University of Utah
Epigenetic Allelic Effects and Computational Ethology: New Paradigms in Behavioral Genetics
February 22, 2017
Daniel Colón-Ramos - Yale University
Actuating memory: how C. elegans remembers a learned behavioral preference
February 15, 2017
Axel Meyer - University of Konstanz
Genomics of adaptations and speciation in the repeated adaptive radiation of cichlid fish
February 8, 2017
Randal Halfmann - Stowers Institute For Medical Research
Proteins be Jammin'
February 1, 2017
Carla Shatz - Stanford University
Saving the Synapse: developmental critical periods and Alzheimer's disease
January 25, 2017
Michael Rosen - University of Texas, Southwestern
Physical Mechanisms of Cell Organization on Micron Length Scales
January 18, 2017
Rachel Green - Johns Hopkins School of Medicine
Interconnections Between Ribosome Activity and mRNA Decay
January 11, 2017
Ariel Bazzini - Stowers Institute For Medical Research
Hidden regulatory code within the genetic code
January 4, 2017
Nikolaus Rajewsky - Berlin Institute for Medical Systems Biology
Knocking out circular RNAs and reconstructing embryos from single cell sequencing
December 14, 2016
Mien-Chie Hung - University of Texas M.D. Anderson Cancer Center
Precision medicine for breast cancer: PARP inhibitor and immune checkpoint threapy
December 7, 2016
Sarah Zanders - Stowers Institute for Medical Research
WTF causes infertility
November 30, 2016
Tom Schilling - University of California, Irvine
A Developmental Achille's Heel: Genetic Analysis of Mechanotransduction in Tendon Development
November 16, 2016
Fyodor Kondrashov - Howard Hughes Medical Institute
Studying the genotype to phenotype connection from an evolutionary perspective
November 9, 2016
John Wallingford - University of Texas, Austin
Planar cell polarity, ciliogenesis, and human disease
November 2, 2016
Julien Sage - Stanford University
Intra-Tumoral heterogeneity in small cell lung cancer
October 26, 2016
Matthew Rockman - New York University
Maternal and zygotic genetics in the evolution of animal development
October 19, 2016
Hopi Hoekstra - Harvard University
Digging for genes that affect behavior in wild mice
October 12, 2016
Hongtao Yu - UT Southwestern
Mitotic regulators in chromosome segregation and insulin signaling
October 5, 2016
David Arnosti - Michigan State University
Close Reading of Enhancers: Lessons from Drosophila
September 28, 2016
Saurabh Sinha - University of Illinois
Modeling of regulatory sequences
September 21, 2016
Neil Shubin - University of Chicago
Putting Your Inner Fish to Work in the Genome
September 14, 2016
Shiv Grewal - National Cancer Institute
Epigenetic genome control by heterochromatin and RNA processing factors
September 7, 2016
Roberto Mayor - University College London
Collective migration of neural crest cells
June 30, 2016
Fyodor Kondrashov - Howard Hughes Medical Institute
May 25, 2016
Chuan He - Chicago University
RNA methylation in gene expression regulation
May 18, 2016
Jennifer Zallen - Memorial Sloan Kettering Cancer Center
Signals and forces that control the dynamics of multicellular systems
May 11, 2016
Coleen Murphy - Princeton University
Insulin signaling, Cognitive Decline, and Reproductive Aging: Quantifying Quality of Life
May 4, 2016
Hiromitsu (Hiro) Nakauchi - Stanford University
Stem cell niche for cells and organs
April 27, 2016
Benjamin Garcia - University of Pennsylvania
Quantitative Proteomics for Understanding Modified Proteins and Proteomes
April 20, 2016
Amit Verma - Albert Einstein College of Medicine
Therapeutic targeting of Myelodysplastic syndromes and acute myeloid leukemia
April 13, 2016
Anne Brunet - Stanford University
The plasticity of lifespan
March 30, 2016
John Stamatoyannopoulos - Washington University
Decoding the Human Genome
March 23, 2016
Yutaka Yoshida - Cincinnati Children's Hospital Medical Center
Synapse elimination and reorganization of corticospinal circuits underlying skilled movements
March 9, 2016
Sandy Schmid - UT Southwestern
Dynamin and the Regulation of Clathrin-Mediated Endocytosis
February 17, 2016
Jane Mellor - University of Oxford
Transcription and RNA Fate
December 2, 2015
Jeff Molkentin - Cincinnati's Children's Hospital
Genetic lineage tracing of the myofibroblast in the mouse
November 18, 2015
Francisco Asturias - Scripps Research Institute
Cryo-EM: An atomic resolution window into Mediator and transcription initiation
November 11, 2015
Peter Walter - University of California, San Francisco
From Protein Folding to Cognition: The Serendipitous Path of Discovery
November 4, 2015
David Pellman - Dana-Farber Cancer Institute/Harvard Medical School
Nuclear Architecture and Genome Stability
October 28, 2015
Mick Bhatia - McMaster University
Competitive Repopulation of the Stem Cell Niche in AML: Implications for Blood Stem Cell Transplantation
October 21, 2015
Jeremy Nathans - Johns Hopkins Medical School
X-chromosome inactivation, color vision, and the female advantage
October 14, 2015
Jordan Raff - Oxford University
How to build a centrosome
October 7, 2015
Barak Cohen - Washington University
Towards a cis-regulatory code
September 30, 2015
Virginia Zakian - Princeton University
21st century genetics: mass Spectrometry of yeast telomerase
September 23, 2015
David Holtzman - Washington University - St. Louis
Potential Role of Extracellular Tau in Development and Spread of Tauopathy: Effects of Anti-Tau Antibodies
September 16, 2015
Matt Gibson - Stowers Institute For Medical Research
Understanding animal origins: epithelial morphogenesis in the sea anemone, Nematostella vectensis
September 9, 2015
Jim Eberwine - University of Pennsylvania, Perelman School of Medicine
Surprises from Single Cell Analysis of Mouse and Human Cells
June 3, 2015
David Scadden - Harvard University
Making blood: the organized labor of multiple niches
May 27, 2015
Norman Iscove - Ontario Cancer Institute
Control of self-renewal in hemopoietic precursor cells
May 20, 2015
Anne Ridley - Kings College, London
Rho GTPases signaling and cell migration
May 6, 2015
Hilary Ashe - University of Manchester
BMP signallng and cell fate specification in Drosophila
April 29, 2015
Feng Zhang - MGovern Institute for Brain Research
Genome Editing Using CRISPR-Cas9
April 15, 2015
Anne-Claude Gingras - Lunenfeld-Tanenbaum Research Institute
Signaling networks in health and disease: a tale of Hippos and mulberries
April 8, 2015
Andras Nagy - Mount Sinai Hospital
Pluripotency in the artificial cell space
April 1, 2015
Stefan Heller - Stanford University
Spatial and temporal trajectories in the developing inner ear resolved with single cell gene expression analysis
March 11, 2015
Thomas Lecuit - Marseille Developmental Biology Institute
Spatial control of tissue mechanics during morphogenesis
March 4, 2015
Or Gozani - Stanford University
An Unexpected Journey: The Lysine Methylome, Epigenetic Signaling and Disease
January 21, 2015
Benoit Bruneau - Gladstone Institute of Cardiovascular Disease
Transcriptional regulation of cardiac lineages
November 19, 2014
Phil Newmark - HHMI, University of Illinois
Germ cell development and regeneration in planarians: implications for understanding parasitic flatworms
November 12, 2014
Stephen Buratowski - Harvard Medical School
Shaping the eukaryotic transcriptome with chromatin and ncRNA transcription
November 5, 2014
Chuck Dorsey - Eli Lilly
Autophagy: Staying in for Dinner
October 29, 2014
David Bilder - University of California, Berkeley
Cold-blooded cancer and Elongating Eggs: Epithelia Function in Development and Disease
October 22, 2014
John Denu - University of Wisconsin
October 15, 2014
Luke Berchowitz - Massachusetts Institute of Technology
Amyloid-mediated translational control is required for meiosis
October 8, 2014
Michael Greenberg - Harvard Medical School
October 1, 2014
Frank Pugh - Pennsylvania State University
Genomic organization of chromatin and the transcription machinery
September 17, 2014
Takashi Nagasawa - Institute for Frontier Medical Sciences, Kyoto University
The microenvironmental niches for hematopoietic stem and progenitor cells in bone marrow
September 10, 2014
Mike Snyder - Stanford University
Personalized Medicine: Personal Omics Profiling During Healthy and Disease States
September 3, 2014
Richard Green - University of California, Santa Cruz
The wonderful worlds of hybrids
May 28, 2014
Dave Raible - University of Washington
Life and death in the lateral line: zebrafish models for hearing loss
May 21, 2014
Liz Robertson - University of Oxford
An expanding job description for the transcriptional repressor Blimp1/Prdm1 in the developing mouse embryo
May 14, 2014
Jeremy Nance - NYU School of Medicine
Mechanisms of contact-induced cell polarity in the C. elegans embryo
May 7, 2014
David Stern - Howard Hughes Medical Institute - Janelia Farm
Why do transcriptional enhancers contain clusters of homotypic transcription factor binding sites?
April 30, 2014
Bob Eisenman - Fred Hutchinson Cancer Research Center
Myc and the Pathway to Cancer
April 23, 2014
Rebecca Heald - University of California, Berkeley
Mechanisms of mitosis and size control in Xenopus
April 16, 2014
Matt Gibson - Stowers Institute for Medical Research
Coordinating mitosis and morphogenesis in proliferating epithelia
April 9, 2014
Michael Shapiro - University of Utah
Endless pigeons most beautiful: evolutionary genomics of Darwin's favorite birds
April 2, 2014
Carl Wu - HHMI, Janelia Farm
Dynamics of histone variants at yeast promoters and centromeres
April 1, 2014
Stefan Heller - Stanford University
March 26, 2014
James Kadonaga - University of California-San Diego
Punctilious Probing of Promoters and Prenucleosomes
March 19, 2014
William Sullivan - University of California, Santa Cruz
Wolbachia, African Riverblindness and Big Sur
March 12, 2014
Rudolf Grosschedl - Max Planck Institute
Transcriptional networks in B lymphopoiesis
March 5, 2014
William Theurkauf - University of Massachusetts Medical School
Building an adaptive genome defense system
February 26, 2014
Robert Braun - The Jackson Laboratory
Mammalian Germline Stem Cells
February 19, 2014
Joshua Levin - Broad Institute of MIT and Harvard
Using RNA-Seq methods for single cells and other challenging samples
February 12, 2014
James Downing - St. Jude Children’s Research Hospital
The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project: Lessons learned
February 5, 2014
Harmit Singh Malik (Cancelled) - Fred Hutchinson Cancer Research Center
Genetic Conflicts Shape Centromeres and Species
January 29, 2014
James Bradner - Harvard Medical School
Chemical Modulation of Chromatin Structure and Function
January 15, 2014
Dean Dawson - Oklahoma Medical Research Foundation
Orienting Chromosomes on the Meiotic Spindle
January 8, 2014
Alcino Silva - Integrative Center for Learning and Memory Brain Research Institute
Molecular, cellular and circuit mechanisms of memory allocation
December 11, 2013
Nelson Spruston - HHMI, Janelia Farm
Dendritic integration, plasticity, and diversity in hippocampal pyramidal neurons
December 4, 2013
David Drubin - University of California, Berkeley
Spatiodynamics of clathrin-mediated endocytosis in yeast and mammals
November 20, 2013
Chuck Dorsey - Lilly Corporate Center
Autophagy: Staying in for Dinner?
November 13, 2013
Tim Hughes - University of Toronto
DNA and RNA binding motifs for mapping gene regulation
November 6, 2013
Wolfgang Baumeister - Max Planck Institute for Biochemistry
Electron Cryomicroscopy: From Molecules to Cells
October 30, 2013
Claus Nerlov - University of Oxford
Pathways and Mechanisms of Hematopoietic Lineage Commitment
October 23, 2013
Alex Gould - National Institute for Medical Research
Food for Thought: nutrients and neural stem cells in Drosophila
October 16, 2013
Randy Reed - Johns Hopkins School of Medicin
Cellular and Molecular Specializations in Sensory Development and Function
October 9, 2013
Sue Jaspersen - Stowers Institute for Medical Research
The Ins and Outs of the Eukaryotic Nucleus
October 2, 2013
Dirk Bohmann - University of Rochester Medical Center
Mechanisms and Functions of Nrf2 Signaling: Stress Defense, Aging, Stem Cells
September 25, 2013
Kausik Si - Stowers Institute for Medical Research
How Long Lasting Memories Are Formed
September 18, 2013
Craig Kaplan - Texas A&M University
Mechanism and Regulation of RNA Polymerase II
September 4, 2013
Mark Biggin - Lawrence Berkeley National Laboratory
Modeling Animal Transcription Networks During Development
May 29, 2013
Vicky Prince - University of Chicago
Zebrafish facial branchiomotor neuron migration: pioneers, followers and those than need guidance
May 22, 2013
Larry Zipursky - University of California, Los Angeles
Cell recognition and the Assembly of Neural Circuits
May 15, 2013
David Wilkinson - MRC National Institute for Medical Research
Roles and mechanisms of boundary formation
May 8, 2013
Tony Hyman - Max Planck Institute
Phase Separation inside the Cytoplasm
May 1, 2013
Stavros Lomvardas - University of California, San Francisco
Molecular mechanisms of olfactory receptor gene choice
April 24, 2013
Erez Raz - Institute of Cell Biology
Motility and Directed Migration of Primordial Germ Cells in Zebrafish
April 17, 2013
Aaron Gitler - Stanford University
High-throughput genetic screens to define mechanisms of human neurodegenerative disease
April 10, 2013
Pavel Tomancak - Max Planck Institute
Patterns of Gene Expression in Development and Evolution
April 3, 2013
Mike Levine - University of California, Berkeley
Transcriptional precision in the Drosophila embryo and evolutionary origins of the neural crest in the Ciona tadpole
March 27, 2013
Dylan Taatjes - University of Colorado
Structural, Molecular and Cellular Mechanism that underlie Transcription Faction function
March 20, 2013
Alexander Stark - Research Institute of Molecular Pathology
Regulatory genomics - decoding Drosophila regulatory sequences
March 13, 2013
Alex Mogilner - University of California, Davis
Mechanical Pathways of Cell Polarization and Motility Initiation
March 6, 2013
Yi Zheng - Cincinnati Children's Hospital Medical Center
Rho GTPases: Physiologic Functions and Translational Implications
February 27, 2013
Claus Nerlov - University of Edinburgh
Pathways and Mechanisms of Hematopoietic Lineage Commitment
February 20, 2013
Martin Hetzer - Salk Institute
Nuclear Membrane Organization and Genome Function
February 13, 2013
David Ginty - Johns Hopkins University School of Medicine
Development and Organization of Neurons that Underlie the Sense of Touch
February 6, 2013
David Grunwald - University of Utah
Development and Organization of Neurons that Underlie the Sense of Touch
January 30, 2013
Joaquin Espinosa - University of Colorado
Rewiring the p53 Network for Effective Cancer Therapies
January 23, 2013
Julie Ahringer - University of Cambridge
Chromatin regulation and the landscape of RNA polymerase II transcription in C. elegans.
January 16, 2013
Donna Fekete - Purdue University
Wnt signaling During Inner Ear Development
January 9, 2013
Tony Kouzarides - Gurdon Institute
Chromatin modifications: Their function and role in cancer
December 12, 2012
John Rubinstein - University of California, San Francisco
Transcriptional Control of Cortical Interneuron Development
December 5, 2012
Kathy Gould - Vanderbilt University
Split decisions: Regulating the end of the cell cycle
November 28, 2012
Nahum Sonenberg - McGill University
Translational control of cancer and autism
November 14, 2012
Douglas Koshland - University of California, Berkeley
Novel intracellular stress and stress response in budding yeast
November 7, 2012
Craig Jordon - University of Rochester, NY
Characterization and Targeting of Leukemia Stem Cells
October 24, 2012
Ali Shilatifard - Stowers Institute For Medical Research
Licensed to Elongate: Transcriptional Elongation Checkpoint Control in Development and Leukemogenesis
October 17, 2012
Kimberly Cooper - Harvard Medical School
Development and Evolution of Form in the Vertebrate Limb
October 10, 2012
Scott Gilbert - Swarthmore College
How the Turtle Gets Its Shell: The Developmental Basis of Evolutionary Novelty
October 3, 2012
Rudolf Jaenisch - Whitehead Institute
Stem Cells, Pluripotency And Nuclear Reprogramming
September 26, 2012
Dieter Soll - Yale University
The Continued Evolution of the Genetic Code
September 19, 2012
Greg Dressler - University of Michigan
Epigenetic Mechanisms of Cell Lineage Specification in Development and Disease
September 12, 2012
Lila Solnica-Krezel - Washington University School of Medicine
Regulation of cell fates and movements during zebrafish gastrulation
September 5, 2012
Stuart Macdonald - University of Kansas
Genomewide Dissection of Complex Trait Variation in Drosophila
June 6, 2012
Christopher Wylie - Cincinnati Children's Hospital Medical Center
A history of germ cell migration: from there to here
May 30, 2012
Chang-Zheng Chen - Stanford University
MiR-181a mediates the control of embryonic stem cell self-renewal
May 25, 2012
Nathan Lawson - University of Massachusetts
Morphogenesis and differentiation in the developing circulatory system
May 24, 2012
Job Dekker - University of Massachusetts
Structure and Stability of Genome
May 23, 2012
Marian Walhout - University of Massachusetts
Gene Regulatory Networks
May 19, 2012
Fred Hutchinson Cancer Research Center
Histone Variant Dynamics and Epigenetics
May 16, 2012
Scott Fraser - California Institute of Technology
Visualizing Complex Events in the Embryo
May 9, 2012
Jean Schaffer - Washington University
Unexpected regulators of metabolic stress
May 2, 2012
Joachim Lingner - Swiss Institute for Experimental Cancer Research
Regulation of telomerase at chromosome ends
April 18, 2012
Leslie Griffith - Brandeis University
Sleep circuits in Drosophila melanogaster
April 11, 2012
Ruth Lehmann - Skirball Institute, New York University
Making and protecting the germline
March 28, 2012
Jing Wang - University of California, San Diego
The hungry fly: From molecules to circuits and olfactory behavior
March 21, 2012
Mike Rout - Rockefeller University
The Hole Picture: Architecture and Mechanism of the Nuclear Pore Complex
March 14, 2012
Sue Biggins - Fred Hutchinson Cancer Research Center
How do cells get the right chromosomes?
March 7, 2012
Alejandro Sánchez - Stowers Institute For Medical Research
New Parts from Old: The Problem of Regeneration
February 29, 2012
Lorna Role - SUNY Stony Brook
Cholinergic modulation of cortico-limbic circuits and behaviors
February 22, 2012
Melanie Cobb - University of Texas - Southwestern
ERKonomics of nutrient sensing
February 15, 2012
Randy Schekman - University of California, Berkeley
Transport vesicle biogenesis: Lessons from yeast applied to mammalian development
February 8, 2012
Kazuhiko Igarashi - Tohoku University School of Medicine
Nuclear function of methionine adenosyltransferase in gene regulation and histone methylation
February 1, 2012
Thomas Look - Harvard Medical School
New Advances Molecular Pathogenesis and Pathway Dependence in T-cell ALL
January 25, 2012
Marianne Bronner - California Institute of Technology
Gene regulatory interactions in neural crest development
January 18, 2012
Luis Aragón - Imperial College London
Roles of Mcd1 sumoylatioin and proteolytic cleavage during DSB repair
January 11, 2012
Ken Sawin - University of Edinburgh
Organizing microtubule organizers
December 14, 2011
Susan Mango - Harvard University
Mother knows best: developmental plasticity during gut formation
December 7, 2011
Jeffrey Trent - Translational Genomics Research Institute
Using Biointelligence to Search the Cancer Genome: Knowledge Recovery Efforts to Move Towards Precision Medical Genomics (PMG)
November 30, 2011
Julie Cooper - London Research Institute
Telomeres as choreographers of chromosome replication, location and segregation
November 16, 2011
Ken Poss - Duke University Medical Center
Deploying zebrafish to understand heart regeneration
November 9, 2011
Gabrielle Kardon - University of Utah Medical School
What do you need to make a muscle? The role of muscle stem cells and connective tissue fibroblasts in muscle development and regeneration
November 2, 2011
Mark Roth - Fred Hutchinson Cancer Research Center
Metabolic Flexibility and Suspended Animation
October 26, 2011
Chris Doe - University of Oregon
Generation of temporal identity in the Drosophila CNS
October 19, 2011
Jonathan Weissman - University of California – San Francisco
New strategies for decoding genomes
October 12, 2011
Tatjana Piotrowski - Stowers Institute for Medical Research
The zebrafish lateral line as a model to study morphogenesis and regeneration
October 5, 2011
Michael Eisen - University of California – Berkeley
Embryos start your engines: Initiating and regulating transcription in the early Drosophila embryo
September 28, 2011
Uwe Ohler - Duke University
Decoding transcription: Genomic and computational approaches in Drosophila
September 21, 2011
Kenro Kusumi - Arizona State University
Evolution of Axial Development and Regeneration: Insights from the Lizard Anolis Carolinensis
September 14, 2011
Piali Sengupta - Brandeis University
Pheromone Signaling in C. elegans: Mechanisms and Consequences
September 7, 2011
Kevin White - University of Chicago
Transcriptional networks in flies and humans: predicting drug targets and patient outcomes
May 25, 2011
Tom Owens-Hughes - University of Dundee
Strategies for Organising Chromogenomes
May 18, 2011
Barbara Meyer - University of California-Berkeley, Howard Hughes Medical Institute
Creating Intimacy: Chromosomal Connections for Gene Expression and Crossovers
May 11, 2011
Robin Allshire - University of Edinburgh
Making CENs of Heterochromatin: rebooting and programming centromeres
May 4, 2011
Angela Gronenborn - University of Pittsburg
Synergy Between NMR and cryoEM - Novel Findings for HIV Capsid Function
April 27, 2011
Andrew Duncan - Oregon Health Science University
The Ploidy Conveyor of Mature Hepatocytes as a Source of Genetic Variation
April 20, 2011
Charles Sherr - St. Jude Children’s Research Hospital, Howard Hughes Medical Institute
Oncogene-mediated Engagement of the ARF-p53 Tumor Suppressor Network
April 13, 2011
Steve Artandi - Stanford University
Telomerase, Stem Cells and Wnt Signaling
April 6, 2011
Gary Bader - University of Toronto
Predicting Protein-Protein Interactions from the Genome for Evolutionary Analysis
March 30, 2011
Joel Goodman - UT Southwestern Medical School
The Lipodystrophy Proteins Lipin And Seipin Control Lipid Droplet Assembly
March 23, 2011
Ted Weinert - University of Arizona
A Misregulated Genome is a Wild, Crazy and Largely Decipherable Place: Stories from Yeast
March 9, 2011
Jennifer Lippincott-Schwartz - National Institutes of Health
Emerging Fluorescence Technology for Analysis of Protein Localization and Organelle Dynamics
March 2, 2011
Judy Berman - University of Minnesota
Genome dynamics in Candida Albicans
February 23, 2011
Mark Rose - Princeton University
Managing Mitosis and Differentiation, Lessons from Yeast Mating
February 16, 2011
Wendy Bickmore - Medical Research Council, UK
Chromatin and Gene Expression: Beyond Histone Modifications and Transcription Initiation
February 9, 2011
Bruce Stillman - Cold Spring Harbor Laboratory
ORC, the Initiator for DNA Replication, Coordinates Chromosome Segregation During Mitosis at Centromeres and Centrosomes
January 26, 2011
Jean-Paul Vincent - National Institute for Medical Research, London
Wnt-Dependent Patterning and Homeostasis in Developing Epithelia
January 19, 2011
Peter Baumann - Stowers Institute for Medical Research
Telomeres and Telomerase – all is well that ends well
January 12, 2011
John Wallingford - University of Texas, Howard Hughes Medical Institute
Planar Cell Polarity: From cell biology to human disease
December 15, 2010
Connie Cepko - Harvard Medical School
Cell Fate Determination in the Vertebrate Retina
December 8, 2010
Ronald Davis - Scripps Research Institute Florida
Optical Imaging of Memory Formation in Drosophila
December 1, 2010
Karen Adelman - National Institute of Environmental Health Sciences
Competition by Design: The Ongoing Battle between Paused Pol II and Nucleosomes for Promoter Occupancy
November 17, 2010
Jasper Rine - University of California-Berkeley, Howard Hughes Medical Institute
Epigenetic Inheritance of Transcriptional States
November 10, 2010
Greg Copenhaver - University of North Carolina
Understanding Meiotic Recombination Using Arabidopsis Tetrads
November 3, 2010
Iswar Hariharan - University of California-Berkeley
Growth, Death and Regeneration: Studies in Drosophila
October 27, 2010
Joan Conaway - Stowers Institute for Medical Research
A Role For The Mediator Of RNA Polymerase Ii Transcription In Elongation Control
October 20, 2010
Tim Mitchison - Harvard Medical School
How does Cancer Chemotherapy Directed at Dividing Cells Really Work?
October 13, 2010
Doug Lowy - National Cancer Institute
Current And Future Preventive HPV Vaccines Against Cervical Cancer And Other HPV-Associated Disease
October 6, 2010
Edward Kravitz - Harvard Medical School
Genetic Manipulations in the Fruit Fly Fight Club: Sex and War in a Single Gene and Other Stories
September 29, 2010
Hitoshi Sakano - University of Tokyo
Neural Map Formation in the Mouse Olfactory System
September 22, 2010
Jerry Workman - Stowers Institute for Medical Research
Protein Complexes that Modify Chromatin for Transcription
September 15, 2010
J.K. Sky Yu - Institute of Cellular and Organismal Biology, Taiwan
Evolution of Genetic Networks Underlying the Emergence of Vertebrate Neural Crest: Insights from Amphioxus
September 8, 2010
Geraldine Seydoux - Johns Hopkins University, Howard Hughes Medical Institute
Breaking Symmetry: Polarization of the C. elegans Embryo
May 26, 2010
Andreas Ladurner - European Molecular Biology Laboratory
Metabolites Connect Cellular Signaling to Chromatin Dynamics
May 19, 2010
Steve Henikoff - Fred Hutchinson Cancer Research Center
Histone Variant Dynamics and Epigenetics
May 12, 2010
James Manley - Columbia University
mRNA Processing: Links to Disease and Other Cellular Processes
May 5, 2010
Karen Oegema - University of California – San Diego
Using C. elegans to Dissect Cell Division Mechanisms
April 28, 2010
Tim Hunt - Cancer Research UK
Getting In and Out of Mitosis
April 21, 2010
David Spector - Cold Spring Harbor Laboratory
Dynamics and Functional Associations of JMJD3, an H3K27 Demethylase
April 14, 2010
Freda Miller - The Hospital for Sick Children, Canada
Skin-derived Precursors: From Morphogenesis to Repair
April 7, 2010
Mark Martindale - University of Hawaii
A Bum’s Up View of Metazoan Body Plan Evolution
March 31, 2010
Stephen Douthwaite - University of Southern Denmark
Resistance to Ribosome-targeting Antibiotics Conferred by Changes in rRNA Methylation
March 24, 2010
Mary Hendrix - Northwestern University
Targeting a Novel Embryonic Pathway to Suppress the Metastatic Phenotype
March 17, 2010
Bruce Baker - Howard Hughes Medical Institute
Sex, Flies and Videotapes
March 10, 2010
John Condeelis - Albert Einstein College of Medicine
Microenvironments of Metastasis: Insights Derived by Multiphoton Imaging
March 3, 2010
Eric Wieschaus - Princeton University
The Mechanics of Cell Shape Change in Drosophila Embryos
February 24, 2010
Manolis Kellis - Massachusetts Institute of Technology
Regulatory Genomics and Epigenomics in Fly and Human
February 17, 2010
Barry Gumbiner - University of Virginia
Cadherins and Catenins in Development and Cancer
February 3, 2010
Brian Black - University of California – San Francisco
Transcriptional Control of Cardiovascular Development
January 27, 2010
Edward Marcotte - University of Texas - Austin
Defining Functional Pathways, Systems, and Networks to Link Genes to Traits and Diseases
January 20, 2010
Tian Xu - Yale University
Deciphering Biology and Disease by Large-scale Genetic Screens in Flies and Mammals
January 13, 2010
Chris Rushlow - New York University
Zelda, a Key Activator of the Early Zygotic Genome in Drosophila
December 9, 2009
Bradley Bernstein - Harvard Medical School
Epigenomic Studies of Normal and Malignant Stem Cells
December 2, 2009
Oliver Hobert - Columbia University, Howard Hughes Medical Institute
Gene Regulatory Mechanisms Controlling Left/Right Asymmetry in the Nervous System of C. elegans
November 18, 2009
James Nelson - Stanford University
Cross-talk between Cell Adhesion Complexes in the Control of Morphogenetic Cell Movements
November 11, 2009
Mark Hochstrasser - Yale University
Cellular Construction of a Protein Machine: Chaperone-assisted Proteasome Assembly
November 4, 2009
Neil Kelleher - University of Illinois
Viewing the Chromatin of Dying Cells through the Lens of Top-Down Mass Spectrometry
October 28, 2009
Elaine Fuchs - Rockefeller University, Howard Hughes Medical Institute
Skin Stem Cells in Morphogenesis and Cancer
October 21, 2009
Steven McKnight - University of Texas Southwestern Medical Center
Mouse Embryonic Stem Cells Exist in a Unique, Threonine-dependent Metabolic State
October 14, 2009
Aseem Ansari - University of Wisconsin
Exploring Gene Regulation through Chemistry and Genomics
October 7, 2009
Russell DeBose-Boyd - University of Texas Southwestern Medical Center
Cholesterol Homeostasis and Sterol-accelerated Degradation of HMG CoA Reductase
September 30, 2009
Fred Chang - Columbia University
Shaping the Fission Yeast Cell
September 23, 2009
Benoit Bruneau - Gladstone Institute of Cardiovascular Disease
Chromatin Remodeling and the Transcriptional Regulation of Heart Development
September 16, 2009
Eddy Rubin - Lawrence Berkeley National Laboratory
Gene Regulation from a Distance
September 9, 2009
Irwin Bernstein - Fred Hutchinson Cancer Research Center
Notch Signaling in Hematopoietic Stem Cells: Basic Findings and Clinical Implications
May 20, 2009
Michael Dyer - St. Jude Children’s Research Hospital
The Role of the Rb Family in Retinal Development and Retinoblastoma
May 6, 2009
Geoff Rosenfeld - University of California - San Diego, Howard Hughes Medical Institute
Life, Death, and Transformation: Repeats, ncRNAs, and Architectural Strategies
April 29, 2009
Bing Ren - Ludwig Institute for Cancer Research
Chromatin Signatures of Transcriptional Enhancers
April 22, 2009
Leslie Loew - University of Connecticut Health Center
The Virtual Cell Project
April 15, 2009
Janet Rossant - The Hospital for Sick Children, Canada
Making the Blastocyst: Early Lineage Development in the Mouse
April 8, 2009
Ken Zaret - Fox Chase Cancer Center
Connecting Inductive Signals to Epigenetics during Endoderm Differentiation
April 1, 2009
John Rawls - University of North Carolina
Host-microbe Relationships in the Zebrafish Digestive Tract
March 25, 2009
Michele Calos - Stanford University
Harnessing Phage Integrases for Gene Therapy and Cell Therapy
March 18, 2009
Bruce Edgar - Fred Hutchinson Cancer Research Center
Gut Homeostasis Mediated by Drosophila Intestinal Stem Cells
March 11, 2009
Randy Johnson - M.D. Anderson Cancer Center
Molecular Genetics of Vertebrate Dorsal-Ventral Limb Patterning
March 4, 2009
Karolin Luger - Colorado State University, Howard Hughes Medical Institute
Posttranslational Modifications as Regulators of Chromatin Structure and Histone Chaperone Function
February 25, 2009
David Morgan - University of California - San Francisco
Finishing the Cell Cycle
February 18, 2009
Magda Konarska - Rockefeller University
Spliceosome Dynamics and Their Impact on the Fidelity of Splice Site Selection
February 11, 2009
Hugo Bellen - Baylor College of Medicine, Howard Hughes Medical Institute
Growth Cone Guidance Receptors and the Pathogenesis of ALS/Lou Gehrig’s Disease
February 4, 2009
Thomas Zwaka - Baylor College of Medicine
Embryonic Stem Cells: Building Alternative Pluripotency Networks
January 28, 2009
Bruce Bradley - Linda Hall Library
Legacy of Science: Rare Books in Kansas City’s Linda Hall Library
January 21, 2009
William Kaelin - Dana-Farber Cancer Institute, Howard Hughes Medical Institute
The von Hippel-Lindau Tumor Suppressor Gene: Insights into Oxygen Sensing and Cancer
January 14, 2009
Sean Eddy - Howard Hughes Medical Institute
HMMR: A New Generation of Homology Search Software
December 10, 2008
Andrea Brand - Wellcome Trust, Cancer Research UK
Self-renewal and Differentiation in the Drosophila Nervous System
December 2, 2008
Alejandro Sánchez Alvarado - University of Utah, Howard Hughes Medical Institute
Dying Young as Late as Possible: Planarians, Regeneration, and Stem Cells
November 19, 2008
Alan Lambowitz - University of Texas at Austin
Mobile Group II Introns: Site-specific Integration into DNA and Applications in Gene Targeting
November 12, 2008
Fiona Watt - Cancer Research – UK, Wellcome Trust Centre for Stem Cell Research
Stem Cell Renewal and Differentiation in Mammalian Epidermis
November 5, 2008
Richard Young - Whitehead Institute
Stem Cell Transcriptional Circuitry and Reprogramming
October 29, 2008
Chad Cowan - Stowers Medical Institute, Harvard Stem Cell Institute
Modeling Disease with Human Pluripotent Cells
October 22, 2008
David Shore - University of Geneva
Exploring Mechanisms of Telomere Length Regulation
October 15, 2008
Philip Benfey - Duke University
Getting to the Root of Developmental Networks
October 8, 2008
Joel Rothman - University of California - Santa Barbara
Specification and Reprogramming of Germ Layer Identity in C. elegans Embryos
October 1, 2008
David Chao - BioMed Valley Discoveries & Stowers Institute for Medical Research
Translational R & D at BioMed Valley Discoveries
September 24, 2008
John DiPersio - Washington University
Stem Cells and T Cells: Optimizing Allogeneic Stem Cell Transplantation
September 17, 2008
Gordon Fishell - New York University
The Developmental Genetic Origins of Cortical Interneurons
September 10, 2008
Jodi Nunnari - University of California - Davis
The Machines that Divide and Fuse Mitochondria
May 21, 2008
William Sly - Saint Louis University
Evolving Therapeutic Targets for Lysosomal Storage Diseases
May 14, 2008
Joe Gall - Carnegie Institution
The Cell Biology of snRNP Biogenesis
May 7, 2008
Josh Kaplan - Harvard Medical School
Synaptic Signaling in C. elegans: MicroRNAs and Seizures
April 30, 2008
Cori Bargmann - Rockefeller University
Assembling a Circuit for Olfactory Behavior
April 23, 2008
Todd Stukenberg - University of Virginia
Processing Spatial Information in the Mitotic Spindle
April 16, 2008
Kevin Struhl - Harvard Medical School
How Proteins Find their Target Sites in vivo: Implications for Epigenetic Inheritance
April 9, 2008
Doug Melton - Harvard University, Howard Hughes Medical Institute
Pancreatic Stem Cells for Development and Diabetes
April 2, 2008
George Daley - Children’s Hospital Boston, Howard Hughes Medical Institute
Customized Pluripotent Stem Cells
March 28, 2008
Blanche Capel - Duke University
The Battle of the Sexes: Patterning the Gonads
March 19, 2008
Peter Lansdorp - British Columbia Cancer Research Centre
Non-random Segmentation of Sister Chromatids
March 12, 2008
Trevor Archer - National Institute of Environmental Health Sciences
Steroid Receptor Mediated Transcriptional Activation within Chromatin
March 5, 2008
David Mangelsdorf - University of Texas Southwestern Medical Center, Howard Hughes Medical Center
Feast to Famine: Nuclear Receptor Control of Metabolism
February 27, 2008
David Toczyski - University of California - San Francisco
Cell Cycle Regulation and the DNA Damage Checkpoint
February 20, 2008
Orna Cohen-Fix - National Institutes of Health
Shaping and Misshaping the Nucleus
February 13, 2008
Nevan Krogan - University of California - San Francisco
Unbiased Biology: Functional Insights from Protein-Protein and Genetic Interaction Datasets
February 6, 2008
Adrian Krainer - Cold Spring Harbor Laboratory
Oncogenic Properties of Alternative Splicing Factors
January 30, 2008
Richard Harland - University of California - Berkeley
BMP Antagonists in Vertebrate Development
January 23, 2008
Ed Munro - University of Washington
Dynamics of Cell Polarization in the Early C. elegans Embryo
January 16, 2008
Jennifer Gerton - Stowers Institute for Medical Research
The Ins and Outs of Chromosome Cohesion
January 9, 2008
David Threadgill - University of North Carolina
Elucidation of Pathological Interactions among the Egfr/Erbb Gene Family Using Mouse Models
December 12, 2007
Andrew Fire - Stanford University
Homology-directed Genetic Surveillance Mechanisms
December 5, 2007
Christof Niehrs - German Cancer Research Center
Regulation of Wnt Signaling at the Plasma Membrane
November 28, 2007
Chunying Du - Stowers Institute for Medical Research
BRUCE: An Inhibitor of Apoptosis Functions in a Non-apoptosis Pathway
November 14, 2007
Jef Boeke - Johns Hopkins University
Networks and Pathways of Lysine Modification
November 7, 2007
Douglas Robinson - Johns Hopkins University
Dynamic Cortical Rearrangements and Mechanosensing during Cell Division
October 31, 2007
Gordon Hager - National Cancer Institute
Genome-wide Interactions of Nuclear Receptors with Chromatin
October 24, 2007
Joe Lutkenhaus - University of Kansas Medical Center
Spatial Regulation of Bacterial Cytokinesis
October 16, 2007
Andrew Murray - Harvard University
Studies on Experimental Evolution in Budding Yeast
October 10, 2007
Weimin Zhong - Yale University
Asymmetric Cell Division and Stem Cell Homeostasis
October 3, 2007
Elliot Elson - Washington University
Matrix Metalloproteinase-1 Acts as a Brownian Ratchet
September 26, 2007
Ali Brivanlou - Rockefeller University
Molecular Basis of Default and Stemness in Human Embryonic Stem Cells
September 19, 2007
Stephen Johnson - Washington University in St. Louis
Growth Control Mechanisms Revealed by the Zebrafish Fin
September 12, 2007
Ueli Schibler - University of Geneva
Circadian Gene Expression: Communication between Central and Peripheral Oscillators
September 5, 2007
Louis Ptacek - University of California - San Francisco, Howard Hughes Medical Institute
Genetic and Molecular Characterization of the Human Circadian Clock
May 30, 2007
John Dick - University of Toronto
The Blood and Guts of Cancer Stem Cells
May 23, 2007
Michael Kastan - St. Jude Children’s Research Hospital
DNA Damage Responses: Mechanisms and Consequences of Failure
May 16, 2007
Luis A. Nunes Amaral - Northwestern University
Cartography Representation of Cellular Processes
May 9, 2007
Douglas Green - St. Jude Children’s Research Hospital
Apoptosis and Mitochondria: The Roads to Ruin
May 2, 2007
Stas Shvartsman - Princeton University
Quantitative Analysis of Developmental Signaling Pathways
April 25, 2007
Claude Desplan - New York University
Detection and Processing of Color Information (in Drosophila)
April 18, 2007
Gerard Evan - University of California - San Francisco Comprehensive Cancer Center
Defining Intrinsic Tumor Suppression Pathways in Cancer
April 11, 2007
Susan Gasser - Friedrich Miescher Institute for Biomedical Research
The Spatial Organization of Repair and Transcription
April 4, 2007
Joshua Sanes - Harvard University
Analyzing Synapse Formation with Mutant and Fluorescent Mice
March 28, 2007
Yigong Shi - Princeton University
Insights into Programmed Cell Death by Structural Biology
March 21, 2007
John Lis - Cornell University
Tracking Transcription Factor Recruitment Dynamics, and Function at Specific Inducible Genes in vivo and in Real Time
March 12, 2007
Denis Duboule - University of Geneva
Engineering Chromosomes to Study Large-scale Gene Regulation during Vertebrate Development
March 7, 2007
Christine Field - Harvard Medical School
Imaging and Biochemistry of Cytokinesis
February 28, 2007
Guillermo Oliver - St. Jude Children’s Research Hospital
Cellular and Molecular Mechanisms Regulating the Development of the Lymphatic Vasculature in Health and Disease
February 21, 2007
Gordon Keller - University Health Network, Toronto
Linage Specific Differentiation of ES Cells in Culture
February 14, 2007
Don Hunt - University of Virginia
Identification of Intact Proteins, Large Peptides, and their Post-translational Modifications on a Chromatographic Time-scale by Using a Combination of Ion/Ion Chemistry and Tandem Mass Spectrometry
February 7, 2007
Craig Peterson - University of Massachusetts
Chromatin Remodeling Machines: Regulators of Transcription and DNA Repair
January 31, 2007
Sharon Dent - M.D. Anderson Cancer Center
In vivo Functions of Histone Modifying Enzymes
January 24, 2007
Barbara Panning - University of California - San Francisco
Non-coding RNA, Chromatin, and Fate Decisions in Embryonic Stem Cells
January 17, 2007
Peter Jackson - Stanford University
Control of the Cell Division by Proteolysis and the Primary Cilium
January 10, 2007
Hermann Steller - Rockefeller University, Howard Hughes Medical Institute
Death by Design: Mechanism and Regulation of Apoptosis
December 13, 2006
Christine Thisse - University of Strasbourg
Patterning the Embryo: From Organizing Centers to Organizing Fields (How to Build an Embryo with Morphogens)
December 6, 2006
Ben Barres - Stanford University
How are CNS Synapses Eliminated?
November 29, 2006
James Hsieh - Washington University
Proteolysis of MLL Family Proteins is Essential for Taspase1-orchestrated Cell Cycle Progression
November 15, 2006
Joshua LaBaer - Harvard Medical School
Functional Proteomics for Biomarker and Target Discovery
November 8, 2006
Robert Murphy - Carnegie Mellon University
Location Proteomics: A Systems Biology Approach to Subcellular Location
November 1, 2006
Gerard Grosveld - St. Jude Children’s Research Hospital
MN1, a New Player in Human Acute Myeloid Leukemia
October 25, 2006
Eric Siggia - Rockefeller University
Fluctuations and the Cell Cycle in Budding Yeast
October 18, 2006
Dan Camerini-Otero - National Institutes of Health
Meiotic DNA Double-strand Break Repair in Mice and Humans
October 11, 2006
Phillip Zamore - University of Massachusetts
RNAi and Other Ancient Pathways Programmed by Small RNAs
October 4, 2006
Andrew Emili - University of Toronto
Cracking the (epi)Proteome Code: Adventures in Proteomics
September 27, 2006
Nicole Le Douarin - Académie des sciences, France
The Neural Crest, a Pluripotent Structure of the Vertebrate Embryo: Developmental and Evolutionary Aspects
September 20, 2006
Mark Winey - University of Colorado
Centrosomes in a Ciliate? The Tetrahymena Basal Body
September 13, 2006
Lila Solnica-Krezel - Vanderbilt University
Genetic Regulation of Gastrulation Movements in Zebrafish
September 6, 2006
Stephen West - Cancer Research UK
Defective DNA Break Repair and Relationship to Human Disease
May 17, 2006
Michael German - University of California - San Francisco
Gene Expression Cascades in Pancreas Development
May 10, 2006
Sally Camper - University of Michigan
Cell Signaling and Transcription Factor Control of Pituitary Cell Fate
May 3, 2006
Pam Silver - Harvard University
Perturbing and Rebuilding Nuclear Networks
April 26, 2006
Jerry Shay - University of Texas Southwestern Medical Center at Dallas
Aging and Cancer: Are Telomeres and Telomerase the Connection?
April 19, 2006
Michael Clarke - Stanford University
Stem Cell Self-renewal and Cancer
April 12, 2006
Eric Olson - University of Texas Southwestern Medical Center at Dallas
Toward a Genetic Blueprint of Cardiovascular Development
April 5, 2006
Thomas Jenuwein - Research Institute of Molecular Pathology
The Epigenome in the Context of the Post-Genomic Era
March 29, 2006
Luis Parada - University of Texas Southwestern Medical Center at Dallas
Modeling Tumors in the Nervous System in Mice
March 15, 2006
Robert Tjian - University of California - Berkeley
Mechanisms of Transcriptional Control and Disease
March 8, 2006
Susan Wente - Vanderbilt University
Nuclear Import and Export: The Rules and the Players
March 1, 2006
Fred Winston - Harvard University
Analysis of Factors that Control Transcription and Chromatin Structure in Yeast
February 22, 2006
Shelley Berger - The Wistar Institute
Factor and Histone Covalent Modifications in Genome Regulation
February 21, 2006
Roger Kornberg - Stanford University
Eukaryotic Gene Transcription
February 15, 2006
Mark Johnston - Washington University
Diabetic Yeasts: Glucose Sensing and Signaling by a Eukaryotic Cell
February 8, 2006
Paul Trainor - Stowers Institute for Medical Research
Craniofacial Development: Unmasking the Origins of Congenital Birth Defects
February 1, 2006
Deborah Yelon - Skirball Institute of Biomolecular Medicine
Building the Zebrafish Heart: From Progenitor Selection to Chamber Expansion
January 25, 2006
Angelika Amon - Massachusetts Institute of Technology, Howard Hughes Medical Institute
Coordinating Chromosome Segregation
January 18, 2006
Barbara Graves - Huntsman Cancer Institute
Routes to Specificity within the ETS Family of Transcription Factors
January 11, 2006
Roy Parker - University of Arizona, Howard Hughes Medical Institute
Control of Translation and mRNA Degradation in Eukaryotic Cells
December 14, 2005
Gunda Georg - University of Kansas
Drug Discovery in Academia: Opportunities and Challenges
December 7, 2005
Ardem Patapoutian - Scripps Research Institute
Molecular Mechanisms of Temperature Sensation
November 30, 2005
Kathrin Plath - Whitehead Institute
Function of Polycomb Group Proteins in Mouse Development
November 16, 2005
Katherine Jones - The Salk Institute
Transcription Induction Mechanisms in Human Disease: Insights from Wnt, Notch, and HIV-1 Tat
November 9, 2005
Scott Hawley - Stowers Institute for Medical Research
How to Hold on to your Partner: Studies of a Simple Meiotic System
November 2, 2005
Liqun Luo - Stanford University
Exploring Neural Circuit Organization and Assembly Using Genetic Mosaics in Flies and Mice
October 26, 2005
Ihor Lemischka and Kateri Moore - Princeton University
Stem Cells and Systems Biology
October 20, 2005
Gary Ruvkun - Harvard University
Using RNAi to Study Itself
October 12, 2005
Thomas Pollard - Yale University
Control of Actin Filament Dynamics during Cytokinesis and Cellular Motility
October 5, 2005
Roberto Dominguez - Boston Biomedical Research Institute
Structural Basis of Actin Cytoskeleton Dynamics
September 28, 2005
Wing Hung Wong - Stanford University
Computational Analysis of Gene Expression and Regulation in ES Cells
September 21, 2005
Daniel Carucci - Foundation for the National Institutes of Health
Grand Challenges in Global Health
September 14, 2005
Ralph Greenspan - The Neurosciences Institute
Sleep, Waking, and Attention in Drosophila
September 7, 2005
Manuel Ares - University of California - Santa Cruz, Howard Hughes Medical Institute
Global Analysis of Splicing Regulation
May 18, 2005
Rudolf Jaenisch - Whitehead Institute
Nuclear Cloning, Stem Cells, and Epigenetic Reprogramming
May 11, 2005
Erin O’Shea - University of California - San Francisco, Howard Hughes Medical Institute
Analysis of the Budding Yeast Proteome
May 4, 2005
Bill Smith - University of Michigan
Cyclooxygenases and the Molecular Basis of the Actions of Essential Fatty Acids
April 27, 2005
Betty Hay - Harvard University
Epithelial-Mesenchymal Transformations: The Signaling Mechanisms that Create Them and the Important Roles They Play in the Embryo
April 20, 2005
John Yates - Scripps Research Institute
Proteomic Mass Spectrometry
April 13, 2005
John Sedat - University of California - San Francisco
The High Resolution Revolution in Light Microscopy: New Insights into Anaphase Chromosome Structure
April 6, 2005
Charlie Boone - University of Toronto
Global Mapping of the Yeast Genetic Interaction Network
March 30, 2005
Edwin Rubel - University of Washington
Developmental Interactions in the Brainstem Auditory Pathways
March 23, 2005
Titia de Lange - Rockefeller University
Protection and Maintenance of Human Telomeres
March 16, 2005
Gary Felsenfeld - National Institutes of Health
Chromatin Boundaries, Chromatin Domains, and Gene Expression
March 9, 2005
Tak Mak - University of Toronto
‘Tis Death That Makes Life Live
March 2, 2005
Bruce Hay - California Institute of Technology
Regulating Cell Death and Cell Differentiation in Drosophila
February 23, 2005
Drew Noden - Cornell University
Head Mesoderm-Neural Crest Interactions: A Story of Victims and Bullies?
February 16, 2005
Mark Henkemeyer - University of Texas Southwestern Medical Center at Dallas
Ephrin Signaling
February 9, 2005
Robin Lovell-Badge - National Institute for Medical Research
How are the Differences Between Males and Females Initiated During Mammalian Development
February 2, 2005
Larry Simpson - University of California - Los Angeles, Howard Hughes Medical Institute
A Complex Business: Uridine Insertion/Deletion RNA Editing in Trypanosome Mitochondria
January 19, 2005
Kennedy Krieger Institute
Repairing the Damaged Cord: From Stem Cell to Activity-based Mechanisms of Recovery
January 12, 2005
Harvard Medical School, Howard Hughes Medical Institute
Signals Patterning the Developing Limb
December 8, 2004
Michael Shen - University of Medicine and Dentistry of New Jersey
Regulation of Nodal Signaling in Mouse Embryogenesis
December 1, 2004
Alan Hinnebusch - National Institutes of Health
Recruitment and Function of Cofactors in Transcriptional Activation by GCN4
November 17, 2004
Tom Gridley - The Jackson Laboratory
Notch Signaling in Mice
November 10, 2004
Roy Jensen - University of Kansas Medical Center
Molecular Analysis of Breast Neoplasia
November 3, 2004
Richard Hanson - Case Western Reserve University
Glyceroneogenesis Revisited
October 27, 2004
David Albertini - University of Kansas Medical Center
Maternal Governance of Embryogenesis in Mammals: Genetic Models of the Signaling Interface between Germ Line and Soma
October 20, 2004
Ray Gesteland - University of Utah
Recoding: Programmed Changes in Decoding
October 13, 2004
Virginia Papaioannou - Columbia University
T-Box Genes in Mouse Development
October 6, 2004
Tony Gorry - Rice University
Information Technology and Behavior
September 29, 2004
Robert Lehman - Stanford University
DNA Replication and Latency in Herpes Viruses
September 22, 2004
Frank Costantini - Columbia University
The Role of GDNF/Ret Signaling in Branching Morphogenesis during Kidney Development
September 8, 2004
Xiaodong Wang - University of Texas Southwestern Medical Center at Dallas, Howard Hughes Medical Center
Biochemical Studies of Apoptosis
June 2, 2004
John Reed - Burnham Institute
Apoptosis Mechanisms
May 26, 2004
Jim Smith - University of Cambridge
Making Mesoderm in the Frog
May 19, 2004
Phil Soriano - Fred Hutchinson Cancer Research Center
Defining the Signaling Specificity of Receptor Tyrosine Kinase Signaling
May 12, 2004
Judith Kimble - University of Wisconsin - Madison, Howard Hughes Medical Institute
Controls of Germline Stem Cells in C. elegans
April 28, 2004
Richard Mann - Columbia University
The Control of Hox Specificity: New Cofactors Among Old Friends
April 21, 2004
David Anderson - California Institute of Technology
Molecular Control of Stem Cell Fate Determination in the Central and Peripheral Nervous System
April 7, 2004
Haringer Singh - University of Chicago, Howard Hughes Medical Institute
Transcriptional Regulation of Cell Fates and Gene Expression in the Immune System
March 31, 2004
Lee Niswander - Sloan-Kettering Institute, Howard Hughes Medical Institute
Understanding Vertebrate Limb and Neural Development Using a Multifaceted Approach
March 24, 2004
Bob Kingston - Harvard University
Functional Analysis of Complexes that Regulate Chromatin Structure and Transcriptional Memory
March 17, 2004
Elaine Fuchs - Rockefeller University
Beauty is Skin Deep: The Biology of the Epidermis and Hair Follicles
March 10, 2004
Alexander Joyner - Skirball Institute, Howard Hughes Medical Institute
Organizing Centers and Compartments Pattern the Nervous System
March 3, 2004
Anne Brunet - Children’s Hospital, Harvard University
The Forkhead Transcription Factors in the Control of Apoptosis, Resistance to Stress, and Organismal Longevity
February 25, 2004
Linheng Li - Stowers Institute for Medical Research
BMP Signaling and Adult Stem Cell Development
February 18, 2004
David Lohnes - Clinical Research Institute of Montreal
Regulation of Cdx1 by Retinoid and wnt Signaling Pathways
February 11, 2004
Sean Carroll - University of Wisconsin - Madison
Molecular Genetics of Animal Evolution
February 4, 2004
Nahum Sonenberg - McGill University
Ribosome Recruitment in Eukaryotes: Regulation of Gene Expression and Cell Growth
January 28, 2004
Anton Berns - Netherlands Cancer Institute
Mouse Models for Cancer
January 21, 2004
Claudio Stern - University College, London
How to Make a Brain: Molecular Dissection of Neural Induction
January 14, 2004
Marian Carlson - Columbia University
Regulation of Snf1/AMPK Kinases and Responses to Metabolic Stress
January 7, 2004
Gary Schoenwolf - University of Utah
Endoderm as a Source of Patterning Information for Early Chick Embryogenesis
December 10, 2003
Brigid Hogan - Duke University
Epithelial-Mesenchymal Cell Interactions and Branching Morphogenesis: The Mouse Lung as a Model System
December 3, 2003
Gail Martin - University of California
Genetic Analysis of FGF Function in Mammalian Embryogenesis
November 19, 2003
David Wilkinson - National Institute for Medical Research, London
Formation and Function of Boundaries in Hindbrain Patterning
November 12, 2003
Thomas Jessell - Columbia University
Control of Motor Neuron Identity and Connectivity
November 5, 2003
Janet Rossant - Mount Sinai Hospital, University of Toronto
Stem Cells and Developmental Pathways in the Early Mouse Embryo
October 29, 2003
Kerry Bloom - University of North Carolina
Mechanisms of Chromosome Segregation
October 15, 2003
David Ish-Horowicz - Cancer Research UK
Taking the A(pical) Train: Mechanisms and Specificity of RNA Trafficking in Drosophila
October 1, 2003
Elizabeth Robertson - Harvard University
Making Heads and Tails of the Early Embryo: TGFPathways Regulating Axis Formation in the Mouse
September 25, 2003
Janet Heasman - Cincinnati Children’s Hospital Medical Center
What my Mother Told Me: Maternal Control of Early Xenopus Development
September 24, 2003
Christopher Wylie - Cincinnati Children’s Hospital Research Foundation
Germ Cells
September 17, 2003
Philip Needleman - Washington University
COX2 Inhibitors: From Discovery to Inflammation and Cancer
September 10, 2003
Nouria Hernandez - Cold Spring Harbor Laboratory, Howard Hughes Medical Institute
CK2 Regulation of Human RNA Polymerase III Transcription in a Well-Defined in vitro Transcription System
September 3, 2003
Christopher Burge - Massachusetts Institute of Technology
Bioinformatics of MicroRNAs
May 28, 2003
Mark Krasnow - Stanford University
Genetic Dissection of Branching Morphogenesis
May 22, 2003
Neal Copeland - National Cancer Institute
Retroviral Tagging Provides a Potent Cancer Gene Discovery Tool in the Post-genome Era
May 21, 2003
Nancy Jenkins - National Cancer Institute
A Genetic Approach to the Study of Vesicle Transport in the Mouse
May 14, 2003
Doug Koshland - Carnegie Institution of Washington
Chromosome Folding and Genome Stability
May 7, 2003
Winship Herr - Cold Spring Harbor Laboratory
Combinatorial Mechanisms of Transcriptional Regulation in Human Cells
April 23, 2003
Skirball Institute, New York University
Germ Line Stem Cell Development in Drosophila
April 16, 2003
Steve McKnight - University of Texas Southwestern Medical Center at Dallas
Reciprocal Coupling of Metabolism and Circadian Rhythm
April 9, 2003
Susan Lindquist - Whitehead Institute
Prions: How Strange Diseases and Strange Genetics Produce New Paradigms in Biology
April 2, 2003
Marty Chalfie - Columbia University
A Molecular Model for Mechanosensation in C. elegans
March 26, 2003
Robert Cohen - University of Kansas
Polarization of the Drosophila Oocyte
March 19, 2003
Minx Fuller - Stanford University
Life's a Niche: Regulation Stem Cell Self-Renewal and Differentiation
March 12, 2003
Malcolm Whitman - Harvard Medical School
Regulation and Function of TGFß Signals during early Embryonic Patterning
March 4, 2003
Monica Justice - Baylor College of Medicine
Mouse Mutagenesis: Defining Gene Function and Modeling Human Disease
February 26, 2003
Margaret Goodell - Baylor College of Medicine
Mammary, Muscle, and Bone Marrow Stem Cells - Biology and Potential Plasticity
February 19, 2003
Joseph Takahashi - Northwestern University
Forward Genetics in the Mouse: Gene Discovery and Functional Analysis of Circadian and Brain Pathways
February 12, 2003
R. Sanders Williams - Duke University
Calcium-regulated Signaling Pathways Control Cellular Mass, Mitochondrial Biogenesis and Gene Expression in Cardiac and Skeletal Myocytes
February 5, 2003
Trudi Schupbach - Princeton University, Howard Hughes Medical Institute
The Control of Signaling through the EGF Receptor in Drosophila Oogenesis
January 29, 2003
Jeff Lichtman - Washington University
Monitoring Synapses in Living Animals
January 22, 2003
Steven Henikoff - Fred Hutchinson Cancer Research Center
Evolution and Dynamics of Variant H3 Histones
January 15, 2003
Nahum Sonenberg - McGill University, Canada
Ribosome Recruitment in Eukaryotes: Regulation of Gene Expression and Cell Growth
January 8, 2003
Brandeis University
Exploring Chromosome Structure by Studying Recombination
December 11, 2002
Ross Cagan - Washington University
Viewing Programmed Cell Death and Oncogenesis through the Eye of a Fly
December 4, 2002
Ting Xie - Stowers Institute for Medical Research
Genetic and Molecular Studies on Stem Cell Regulation in Drosophila
November 20, 2002
Ken Peterson - University of Kansas Medical Center
Molecular Control of Human ß-globin Gene Switching
November 13, 2002
Thomas Sudhof - University of Texas Southwestern Medical Center at Dallas
Ca2+ Regulation of Synapse Function
November 6, 2002
Oliver Hobert - Columbia University
Axonal Organization in the Nervous System Relies on a Dedicated Maintenance Mechanism
October 30, 2002
Kees Weijer - Wellcome Trust Biocentre, University of Dundee
Chemotaxis and its Role in Gastrulation in the Chick
October 23, 2002
Ian Willis - Albert Einstein College of Medicine
Activation and Repression of Transcription by RNA Polymerase III
October 16, 2002
Norbert Perrimon - Harvard Medical School, Howard Hughes Medical Institute
Functional Genomics in Drosophila: Highthroughput RNAi Screens in Drosophila Cells
October 9, 2002
Tom Petes - University of North Carolina
Genetic Regulation of Genome Stability in Yeast
October 2, 2002
Michael Rosbash - Brandeis University, Howard Hughes Medical Institute
Connections Between Transcription and RNA Processing
September 25, 2002
Marianne Bronner-Fraser - California Institute of Technology
Induction of the Neural Crest
September 18, 2002
Helen Hobbs - University of Texas Southwestern Medical Center at Dallas
Genetic Defenses Against Sterol Accumulation
September 11, 2002
Mary Faith Marshall - University of Kansas Medical Center
Demagoguery, Ideology, and Rhetoric: The Politics of Stem Cell Research
September 4, 2002
Yi Rao - Washington University
Signal Transduction Mechanisms Guiding Cell Migration in the Nervous System
May 29, 2002
Natalie Ahn - University of Colorado at Boulder
New Avenues in MAP Kinase Signal Transduction
May 22, 2002
Bill McGinnis - University of California, San Diego
Hox Protein Mutation and Macroevolution of the Insect Body Plan
May 15, 2002
Jerry Workman - Pennsylvania State University, Howard Hughes Medical Institute
Functions and Interactions of Histone Acetyltransferase Complexes and the SWI/SNF Complex in Yeast
May 8, 2002
Andy McMahon - Harvard University
Hedgehog Signaling in the Vertebrate Embryo
May 1, 2002
Jiyan Ma - University of Chicago
Exploring the Cellular Mechanism of Prion Disease: Misfolding and Retrograde Transport of PrP Generates a Neurotoxic PrPSc-like Conformation
April 24, 2002
Margaret Baron - New York University
Programming the Embryo to Make Blood and Vascular Endothelial Cells
April 17, 2002
Paul Kelly - University of Kansas
Signaling Pathways that Regulate Synaptic Transmission in Brain
April 10, 2002
Bill Skarnes - University of California - Berkeley
Functional Analysis of the Mammalian Genome
April 3, 2002
Eric Olson - University of Texas Southwestern Medical Center at Dallas
Transcriptional Control of Heart Development and Disease
March 27, 2002
John Heuser - Washington University
The Ultrastructural Basis of Cancer Cell Invasiveness
March 20, 2002
Steve Johnson - Washington University
How the Zebrafish Gets its Stripes
March 13, 2002
Mark Noble - University of Rochester, New York
Pivotal Roles of Redox Regulation in Precursor Cell Function and Neoplasia
March 6, 2002
Pamela Geyer - University of Iowa
Insulators: A New Class of Elements that Establish Independent Domains of Gene Function
February 27, 2002
Jeffrey Milbrandt - Washington University
Development, Regeneration and Tumorigenesis: Mechanistic Insights from Gene Targeting and Expression Profiling
February 20, 2002
Robert G. Roeder - The Rockefeller University
Regulation of Transcription in Animal Cells through the Action of Diverse Coactivators
February 13, 2002
Joseph Goldstein and Michael Brown - University of Texas Southwestern Medical Center at Dallas
How Cells Control Cholesterol
February 6, 2002
David Ornitz - Washington University
FGF and FGF Receptor Signaling in Skeletal Development and Genetic Disease
January 23, 2002
Gary Stormo - Washington University
Experimental and Computational Methods for Identifying Regulatory Sites in DNA Sequences
January 16, 2002
Scott Saunders - Washington University
Heparan Sulfate Proteoglycans: Master Regulators of Cellular Responsiveness to Growth Factors and Morphogens
January 9, 2002
Rick Young - Massachusetts Institute of Technology, Whitehead Institute
Mapping Genome Regulatory Circuitry
December 12, 2001
Joshua Sanes - Washington University
Synapse Formation Analyzed in Fluorescent and Mutant Mice
December 5, 2001
Stan Fields - University of Washington, Howard Hughes Medical Institute
Using Yeast to Analyze the Interactions of Proteins, Nucleic Acids and Small Molecules
November 28, 2001
Ali Shilatifard - St. Louis University School of Medicine
COMPASS: A SET Domain Containing Trithorax Related Complex Involved in Transcriptional Regulation and Oncogenesis
November 14, 2001
Nancy Bonini - University of Pennsylvania, Howard Hughes Medical Institute
Drosophila as a Model for Human Neurodegenerative Disease
November 7, 2001
Robert Haley - University of Texas Southwestern Medical Center at Dallas
Gulf War Syndrome: A Toxic Cellular Inquiry to Deep Brain Structures
October 24, 2001
Ed Ziff - New York University School of Medicine
Regulating the Strength of Synapses through Trafficking of Glutamate Receptors
October 17, 2001
Donald Riddle - University of Missouri - Columbia
Genetics of Development and Longevity in C. elegans
October 10, 2001
Beth Sullivan - The Salk Institute
Structure and Function of Centromeric Chromatin in Flies and Humans
October 3, 2001
Kevin Moore - Oklahoma Medical Research Foundation
Biochemistry of Leukocyte-Endothelial Interactions
September 26, 2001
Thomas O’Halloran - Northwestern University
Chemical Biology of Intracellular Transition Metals in Human Disease
September 19, 2001
Stephen Alexander - University of Missouri - Columbia
Proteomic and Genetic Approaches to studies of Regulated Protein Secretion to Anticancer Drugs
September 5, 2001
Alan Spradling - Carnegie Institute
Regulation of Cell Differentiation During Early Stages of Drosophila Oogenesis
June 6, 2001
Alfred G. Gilman - University of Texas Southwestern Medical Center at Dallas
May 30, 2001
Thom Kaufman - Indiana University, Howard Hughes Medical Institute
Hox Genes and the Arthopodan Bauplan
May 16, 2001
Randy Johnson - University of Texas, MD Anderson Cancer Center
Vertebrate Segmentation and Pattern Formation
May 9, 2001
Bruce Lahn - University of Chicago, Howard Hughes Medical Institute
Comparative Genomics: A New Tool for Studying Genome Function and Evolution
May 2, 2001
Luis Parada - University of Texas Southwestern Medical Center at Dallas
Neurotrophin Ligands and their Receptors in the Survival of Early Neurons
April 11, 2001
Barry Festoff - University of Kansas Medical Center
Conformational Neurodegenerative Diseases: Role of Proteases and Transglutaminases in Model Systems
March 28, 2001
Kelley Thomas - University of Kansas Medical Center
Mutation Accumulation in the c.Elegans Genome
March 21, 2001
Alan Godwin - University of Kansas Medical Center
Hoxc 13: Hair Today, Gone Tomorrow
March 14, 2001
Edward (Ward) Wakeland - University of Texas Southwestern Medical Center at Dallas
Mouse Genetics in the Context of a Mouse Model of SLE
March 7, 2001
Brian Livingston - University of Missouri - Kansas City
Regulation of Transcription during Endoderm Development in Sea Urchins
February 28, 2001
S. K. Dey - University of Kansas Medical Center
Molecular Signaling in Embryo-Uterine Interactions During Implantation
February 21, 2001
Jill Pelling - University of Kansas Medical Center
Molecular Mechanism of Chemoprevention by the Bioflavonoid Apigenin: Post-translational Stabilization of the p53 Tumor Suppressor Protein
February 14, 2001
Skip Garner - University of Texas Southwestern Medical Center at Dallas
Informatics and Instrumentation for the Post-genome Era
February 7, 2001
Jeff Price - University of Missouri - Kansas City
Doubletime: A Protein Kinase that Establishes the Molecular Oscillations of Circadian Rhythms
January 31, 2001
Glen Andrews - University of Kansas Medical Center
Mechanisms of Regulation of Gene Expression by Zinc
January 24, 2001
Charles Little - University of Kansas Medical Center
Vasculogenesis: Formation of the First Blood Vessels
January 10, 2001
Brian Sauer - Oklahoma Medical Research Foundation
Cre Recombinase and Mouse Genetics by Design
December 4, 2000
Paul Trainor - National Institute for Medical Research, London
Craniofacial Development: The Role of Neural Crest and Hox Gene Plasticity
November 29, 2000
Doug Cyr - University of Alabama at Birmingham
Roles for Hsp70 in CFTR Folding and Proteosomal Degradation