Development is a highly complex coordination of gene activity, molecular function, and cellular behavior that occurs over a relatively brief period. Stowers scientists are investigating these processes and how they can be disrupted. By studying research organisms that are genetically and developmentally similar to humans, scientists are uncovering insights into the origins of and potentially new ways to address many of these conditions.

The Kostova Lab

Ribosomes are molecular machines that make all the proteins of the body. Ribosome structure and function can vary dramatically across cell types and at different times in the same cell, driving developmental processes and the many different functions cells must perform. When ribosomes stop working or do not assemble correctly, they can cause congenital conditions or diseases like cancer and are even linked to Alzheimer’s. Listen to Stowers Assistant Investigator Kamena Kostova, Ph.D., discuss her research on ribosomes and how it can impact human health.