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Leanne Wiedemann

Ph.D., Biochemistry, Ohio State University

Portrait of Leanne Wiedemann

Leanne Wiedemann, Ph.D., is a staff scientist in the laboratory of Robb Krumlauf, Ph.D. She also serves as the research degree coordinator for the Open University affiliated graduate program at Stowers. She holds an affiliate faculty position in the Department of Pathology and Laboratory Medicine at the University of Kansas School of Medicine.

Her research focus is to understand how cells know where they are in the body and what they should become. Wiedemann investigates the regulatory basis of tissue patterning and morphogenesis during development, disease, and evolution. She explores gene networks using diverse genetic, genomic, biochemical, and imaging approaches. She also exploits the extensive conservation in hindbrain and somite segmentation between vertebrates by utilizing a variety of other model systems (human cells, chick, zebrafish, and lamprey) to investigate similarities and differences in patterning processes during vertebrate evolution.

Featured Publications

Comparison of antibody levels in response to SARS-CoV-2 infection and vaccination type in a midwestern cohort.

Remy, L., Tomomori-Sato, C., Conkright-Fincham, J., Wiedemann, L.M., Conaway, J.W., and Unruh, J.R. medRxiv, 2021.2008.2016.21262036. doi:10.1101/2021.08.16.21262036

Inter-rhombomeric interactions reveal roles for fibroblast growth factors signaling in segmental regulation of EphA4 expression

Cambronero F, Ariza-McNaughton L, Wiedemann LM, Krumlauf R. Dev Dyn. 2020;249:354-368.

A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates

Parker HJ, De Kumar B, Green SA, Prummel KD, Hess C, Kaufman CK, Mosimann C, Wiedemann LM, Bronner ME, Krumlauf R. Nat Commun. 2019;10:1189. doi: 1110.1038/s41467-41019-09197-41468.

The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution

Smith JJ, Timoshevskaya N, Ye C, Holt C, Keinath MC, Parker HJ, Cook ME, Hess JE, Narum SR, Lamanna F, Kaessmann H, Timoshevskiy VA, Waterbury CKM, Saraceno C, Wiedemann LM, Robb SMC, Baker C, Eichler EE, Hockman D, Sauka-Spengler T, Yandell M, Krumlauf R, Elgar G, Amemiya CT. Nat Genet. 2018;50:270-277.  Publisher CorrectionNat Genet. 2018;50:768.


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