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Supporting the scientific spirit of transparency, the Stowers Institute for Medical Research makes the data underlying its scientific publications freely accessible to the scientific community. Access to original, unprocessed data allows other scientists to validate and extend findings made by Stowers researchers.


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Characterization of a metazoan ADA acetyltransferase complex

Soffers JHM, Li X, Saraf A, Seidel CW, Florens L, Washburn MP, Abmayr SM, Workman JL. Nucleic Acids Res. 2019;47:3383-3394.

MPTAC Determines APP Fragmentation via Sensing Sulfur Amino Acid Catabolism

Suganuma T, Swanson SK, Gogol M, Garrett TJ, Conkright-Fincham J, Florens L, Washburn MP, Workman JL. Cell Rep.2018;24:1585-1596.

Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response.

Oh S, Suganuma T, Gogol MM, Workman JL. eLife.2018;7:e36157. doi: 36110.37554/eLife.36157.

Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in Drosophila gene expression and development

Li X, Seidel CW, Szerszen LT, Lange JJ, Workman JL, Abmayr SM. Genes Dev.2017;31:1588-1600.

Myeloid Leukemia Factor acts in a chaperone complex to regulate transcription factor stability and gene

Dyer JO, Dutta A, Gogol M, Weake VM, Dialynas G, Wu X, Seidel C, Zhang Y, Florens L, Washburn MP, Abmayr SM, Workman JL. J Mol Biol.2017;429:2093-2107.

Composition and Function of Mutant Swi/Snf Complexes

Dutta A, Sardiu M, Gogol M, Gilmore J, Zhang D, Florens L, Abmayr SM, Washburn MP, Workman JL. Cell Rep. 2017;18:2124-2134.​

Chromatin remodeler Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation

Lee J, Shik Choi E, David Seo H, Kang K, Gilmore JM, Florens L, Washburn MP, Choe J, Workman JL, Lee D. Nat Commun.2017;8:14527. doi: 14510.11038/ncomms14527.

Role of Nhp6 and Hmo1 in SWI/SNF occupancy and nucleosome landscape at gene regulatory regions

Hepp MI, Smolle M, Gidi C, Amigo R, Valenzuela N, Arriagada A, Maureira A, Gogol MM, Torrejon M, Workman JL, Gutierrez JL. Biochim Biophys Acta.2017;1860:316-326..

Selective suppression of antisense transcription by Set2-mediated H3K36 methylation

Venkatesh S, Li H, Gogol MM, Workman JL. Nat Commun.2016;7:e13610. doi: 13610.11038/ncomms13610.

Limiting PCNA-unloading at the G1/S transition

Huang F, Abmayr SM, Workman JL. Limiting PCNA-unloading at the G1/S transition. Cell Cycle.2016;15:3001-3002.

Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module

Li W, Atanassov BS, Lan X, Mohan RD, Swanson SK, Farria AT, Florens L, Washburn MP, Workman JL, Dent SY. Mol Cell Biol. 2016;36:2855-2866.

Egf signaling directs neoblast repopulation by regulating asymmetric cell division in planarians

Lei K, Thi-Kim Vu H, Mohan RD, McKinney SA, Seidel CW, Alexander R, Gotting K, Workman JL, Sánchez Alvarado A. Dev Cell. 2016;38:413-429.

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

Gilmore JM, Sardiu ME, Groppe BD, Thornton JL, Liu X, Dayebgadoh G, Banks CA, Slaughter BD, Unruh JR, Workman JL, Florens L, Washburn MP. PloS One. 2016;11:e0155492. doi: 0155410.0151371/journal.pone.0155492.

The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition

Huang F, Saraf A, Florens L, Kusch T, Swanson SK, Szerszen LT, Li G, Dutta A, Washburn MP, Abmayr SM, Workman JL. Genes Dev. 2016;30:1198-1210.

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth

Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY.  Mol Cell. 2016;62:558-571.

Moco biosynthesis and the ATAC acetyltransferase engage translation initiation by inhibiting latent PKR activity.

Suganuma T, Swanson SK, Florens L, Washburn MP, Workman JL. J Mol Cell Biol. 2015;8:44-50.

Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism.

Li S, Swanson SK, Gogol M, Florens L, Washburn MP, Workman JL, Suganuma T. Mol Cell. 2015;60:408-421.

New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes

Salomon-Kent R, Marom R, John S, Dundr M, Schiltz LR, Gutierrez J, Workman J, Benayahu D, Hager GL. J Cell Physiol.2015;230:2270-2280.

Histone acetyltransferase Enok regulates oocyte polarization by promoting expression of the actin nucleation factor spire.

Huang F, Paulson A, Dutta A, Venkatesh S, Smolle M, Abmayr SM, Workman JL. Genes & Dev. 2014;28:2750-2763.

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Histone modification as a reflection of metabolism

Suganuma T, Workman JL. Cell Cycle.2016;15:481-482.

Histone exchange, chromatin structure and the regulation of transcription.

Venkatesh S, Workman JL. Nat Rev Mol Cell Biol. 2015;16:178-189.

The expanding role for chromatin and transcription in polyglutamine disease.

Mohan RD, Abmayr SM, Workman JL. Curr Opin Genet Dev. 2014;26C:96-104.

Emerging Areas of Chromatin Research

Suganuma T. In: JL Workman, and SM Abmayr, eds. Fundamentals of Chromatin. New York, NY: Springer; 2014.

Transcription Through Chromatin

Smolle M, Venkatesh S. Transcription Through Chromatin. In: JL Workman, and SM Abmayr, eds. Fundamentals of Chromatin. New York, NY: Springer; 2014:427-489.

Reading Histone Modifications

Ruan C, Li B. Reading Histone Modifications. In: JL Workman, and SM Abmayr, eds. Fundamentals of Chromatin. New York, NY: Springer; 2014:355-373.

Histone Ubiquitylation Control of Gene Expression

Weake V, Abmayr SM, Workman JL. In: SM Abmayr, and JL Workman, eds. Fundamentals of Chromatin. New York, NY: Springer; 2014:257-307.

Fundamentals of Chromatin

Workman JL, Abmayr SM, eds. New York, Springer. 2014.

Recognizing methylated histone variant H3.3 to prevent tumors.

Venkatesh S, Workman JL. Cell Res. 2014;24:649-660.

Pulling complexes out of complex diseases: Spinocerebellar Ataxia 7.

Mohan RD, Abmayr SM, Workman JL. Rare Dis. 2014;2:e28859.

Remodelling without a power stroke.

Dutta A, Workman JL. EMBO Rep.2013;14:1030-1031.

Nucleosome Remodeling and Epigenetics

Becker PB, Workman JL. Cold Spring Harb Perspect Biol. 2013;5:a017905. doi: 017910.011101/cshperspect.a017905.

Directing transcription to the right way.

Huang F, Workman JL. Cell Res. 2013;23:1153-1154.

Malaria: Molecular secrets of a parasite.

Venkatesh S, Workman JL, Wahlgren M, Bejarano MT. Nature. 2013;499:156-157.

UpSETing chromatin during non-coding RNA production.

Venkatesh S, Workman JL, Smolle M. Epigenetics Chromatin. 2013;6:16.

Chromatin and Signaling.

Suganuma T, Workman JL. Curr Opin Cell Biol. 2013;25:322-326.

reSETting chromatin during transcription elongation.

Smolle M, Workman JL, Venkatesh S. Epigenetics

Non-coding transcription SETs up regulation.

Venkatesh S, Workman JL. Cell Res. 2013;23:311-313.

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