Leanne Wiedemann, PhD
Staff Scientist
Professor, Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine

PhD, Biochemistry, Ohio State University

Areas of Interest 
Developmental Biology, Evolutionary Biology, Nervous System Development, Gene Regulation
Profile 

Leanne Wiedemann, PhD, is a staff scientist in the laboratory of Robb Krumlauf, PhD. She also serves as the research degree coordinator for the Open University affiliated graduate program at Stowers. She holds an affiliate faculty position in the Department of Pathology and Laboratory Medicine at the University of Kansas School of Medicine.

Research Summary 

The simplest explanation of the focus of our research is to understand the how cells know where they are in the body and what they should become. The more complex description is to understand the regulatory basis of tissue patterning and morphogenesis during development, disease, and evolution. We explore gene networks using diverse genetic, genomic, biochemical, and imaging approaches. We also exploit the extensive conservation in hindbrain and somite segmentation between vertebrates by utilizing a variety of other model systems (human cells, chick, zebrafish, and lamprey) to investigate similarities and differences in patterning processes during vertebrate evolution.

Featured Publications 
Cambronero F, Ariza-McNaughton L, Wiedemann LM, Krumlauf R. Dev Dyn. 2020;249:354-368.
Parker HJ, De Kumar B, Green SA, Prummel KD, Hess C, Kaufman CK, Mosimann C, Wiedemann LM, Bronner ME, Krumlauf R. Nat Commun. 2019;10:1189. Doi: 1110.1038/s41467-41019-09197-41468.
Smith JJ, Timoshevskaya N, Ye C, Holt C, Keinath MC, Parker HJ, Cook ME, Hess JE, Narum SR, Lamanna F, Kaessmann H, Timoshevskiy VA, Waterbury CKM, Saraceno C, Wiedemann LM, Robb SMC, Baker C, Eichler EE, Hockman D, Sauka-Spengler T, Yandell M, Krumlauf R, Elgar G, Amemiya CT. Nat Genet. 2018;50:270-277. Publisher Correction: Nat Genet. 2018;50:768. 
Smith JJ, Kuraku S, Holt C, Sauka-Spengler T, Jiang N, Campbell MS, Yandell MD, Manousaki T, Meyer A, Bloom OE, Morgan JR, Buxbaum JD, Sachidanandam R, Sims C, Garruss AS, Cook M, Krumlauf R, Wiedemann LM, Sower SA, Decatur WA, Hall JA, Amemiya CT, Saha NR, Buckley KM, Rast JP, Das S, Hirano M, McCurley N, Guo P, Rohner N, Tabin CJ, Piccinelli P, Elgar G, Ruffier M, Aken BL, Searle SM, Muffato M, Pignatelli M, Herrero J, Jones M, Brown CT, Chung-Davidson YW, Nanlohy KG, Libants SV, Yeh CY, McCauley DW, Langeland JA, Pancer Z, Fritzsch B, de Jong PJ, Zhu B, Fulton LL, Theising B, Flicek P, Bronner ME, Warren WC, Clifton SW, Wilson RK, Li W. Nat Genet. 2013;45:415-421, 421e411-412.
© 2021 Stowers Institute for Medical Research