Researchers at the Workman Lab at the Stowers Institute for Medical Research discovered that the highly conserved coactivator SAGA plays an important role in tissue-specific gene expression in fruit flies.
The Shilatafard Lab has found that an assembly of transcription elongation factors known as Super Elongation Complex helps paused RNA polymerases to come online and start transcribing the gene ahead.
Renowned developmental biologist Tatjana Piotrowski, Ph.D., and trailblazing regeneration expert Alejandro Sánchez Alvarado, Ph.D., joined the Stowers Institute for Medical Research.
Investigator R. Scott Hawley, PhD, has been elected a member of the National Academy of Sciences for his excellence in original scientific research.
A report from the Conaway lab at the Stowers Institute for Medical Research identifies a switch that allows RNA polymerase to shift gears from neutral into drive and start transcribing.