Researchers at the Stowers Institute teased apart the molecular mechanisms enabling stem cell renewal in hematopoietic stem cells and applied their insight to expand cultured hematopoietic stem cells a hundredfold.
Researchers at the Stowers Institute report that a powerful intracellular stream pushes chromosomes off center in preparation for the highly asymmetric cell division that completes oocyte maturation upon fertilization of the egg.
The time-consuming task of "flipping flies" has been taken over by a custom-designed, fully automated live-transfer robot recently installed at the Stowers Institute for Medical Research.
Using the flatworm Schmidtea mediterranea as an eexample, researchers at the Stowers Institute demonstrated how our distant evolutionary cousins regenerate their excretory systems from scratch.
Researchers at the Workman Lab at the Stowers Institute for Medical Research discovered that the highly conserved coactivator SAGA plays an important role in tissue-specific gene expression in fruit flies.
The Shilatafard Lab has found that an assembly of transcription elongation factors known as Super Elongation Complex helps paused RNA polymerases to come online and start transcribing the gene ahead.
Renowned developmental biologist Tatjana Piotrowski, Ph.D., and trailblazing regeneration expert Alejandro Sánchez Alvarado, Ph.D., joined the Stowers Institute for Medical Research.
Investigator R. Scott Hawley, PhD, has been elected a member of the National Academy of Sciences for his excellence in original scientific research.
A report from the Conaway lab at the Stowers Institute for Medical Research identifies a switch that allows RNA polymerase to shift gears from neutral into drive and start transcribing.